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Flow and atherosclerosis in coronary bifurcations
EuroIntervention, 2010Coronary bifurcations are among the most frequent sites affected by atherosclerosis. In these regions, complex haemodynamic conditions prevail and local flow disturbances dictate the localisation and progression of atheroma. Endothelial shear stress (ESS) is the main flow-related factor affecting the distribution of atherosclerosis in a bifurcation ...
Yiannis S. Chatzizisis+3 more
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Journal of the American Medical Association (JAMA), 1987
The Cholesterol-Lowering Atherosclerosis Study (CLAS) was a randomized, placebo-controlled, angiographic trial testing combined colestipol hydrochloride and niacin therapy in 162 nonsmoking men aged 40 to 59 years with previous coronary bypass surgery ...
D. Blankenhorn+5 more
semanticscholar +1 more source
The Cholesterol-Lowering Atherosclerosis Study (CLAS) was a randomized, placebo-controlled, angiographic trial testing combined colestipol hydrochloride and niacin therapy in 162 nonsmoking men aged 40 to 59 years with previous coronary bypass surgery ...
D. Blankenhorn+5 more
semanticscholar +1 more source
Spontaneous coronary atherosclerosis in birds
Journal of Atherosclerosis Research, 1963Summary The coronary arteries of commercially raised white Leghorn cockerels and hens were dissected, embedded in gelatin and studied. Stated age was between 2 and 3 years. Fibrotic lesions were found with lipids in the base of the more severe plaques.
B. Lema, S.J. Kaplan, M.R. Malinow
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Type A behaviour and coronary atherosclerosis
Journal of Psychosomatic Research, 1988The relation of the Type A behaviour pattern to coronary atherosclerosis was assessed in a sample of 519 coronary angiography patients. Type A measures were the Structured Interview and the Framingham questionnaire. Angiographic indices included a composite coronary occlusion index and number of coronary vessels significantly diseased.
Pauline Langeluddecke+3 more
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Prevention of Coronary Atherosclerosis
1985In 1970 the Intersociety Commission on Heart Diseases predicted that “coronary heart disease has reached enormous proportions … [and] will result in coming years in the greatest epidemic mankind has faced unless we are able to reverse the trend by concentrated research into its cause and prevention” [1]. The scientific community has indeed responded to
Peter F. Cohn, R. Curtis Ellison
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Experimental coronary atherosclerosis in rabbits
Atherosclerosis, 1970Abstract Intermittent cholesterol feeding of mature rabbits for periods of 6–30 months has produced atherosclerotic lesions of the main coronary arteries apprently similar to those found in man. The advantages of the rabbit as an experimental animal are stressed. Individual variations in response to cholesterol feeding were observed.
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ATHEROSCLEROSIS AND CORONARY THROMBOSIS
The Lancet, 1961A.N. Howard, G.A. Gresham
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Coronary spasm and coronary atherosclerosis
The American Journal of Cardiology, 1981Bernard Lown, William H. Gutstein
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Hypertension and coronary atherosclerosis [PDF]
Hypertension is a major contributor to the development of coronary arterial disease and its major complications. Patients with hypertension have at least a two-fold increase in risk for myocardial infarction, angina pectoris, and sudden death [1, 2]. Even mild elevations in blood pressure appear to accelerate the development of these problems.
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Atherosclerosis in the coronary arteries of rats
Journal of Atherosclerosis Research, 1964Summary Groups of albino and hooded rats were fed diets containing between 10 % and 30 % butter, and 10 % and 22 % groundnut oil, for periods from 14 to 20 months. Other groups were maintained on stock cubes throughout life. Out of a total of 143 animals, 87 had atheromatous plaques in the coronary arteries. The amount or type of fat in the diet had
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