Results 21 to 30 of about 1,113,564 (363)

Extracellular Matrix Targeted MRI Probes

Analysis &Sensing, Volume 3, Issue 1, January 2023., 2023
Gadolinium based MRI probes targeted to ECM components, either proteins or enzymes, hold promise for accurate molecular characterization and staging of fibrotic diseases in vivo. Non‐covalent binding probes (1), reactive probes (2), and enzyme‐responsive probes (3) are discussed.
Giuseppe Digilio, Sara Lacerda, Begoña Lavin Plaza, Alkystis Phinikaridou   +3 more
wiley   +1 more source

Imaging of the calcium activated potassium channel 3.1 (KCa3.1) in vivo using a senicapoc‐derived positron emission tomography tracer

Archiv der Pharmazie, Volume 355, Issue 12, December 2022., 2022
The 18F‐labeled derivative [18F]3 of senicapoc was synthesized using the prosthetic group approach with 1‐azido‐2‐[18F]fluoroethane ([18F]6) in a “click” reaction. The biological activity of the new positron emission tomography tracer was evaluated in vitro and in vivo.
Christian P. Konken, Kathrin Heßling, Insa Thale, Sonja Schelhaas, Jennifer Dabel, Sarah Maskri, Etmar Bulk, Thomas Budde, Oliver Koch, Albrecht Schwab, Michael Schäfers, Bernhard Wünsch   +11 more
wiley   +1 more source

Novel Approaches for Predicting Risk Factors of Atherosclerosis [PDF]

Biomedical and Health Informatics, IEEE Journal of , vol.17, no.1, pp.183,189, Jan. 2013, 2015
Coronary heart disease (CHD) caused by hardening of artery walls due to cholesterol known as atherosclerosis is responsible for large number of deaths world-wide. The disease progression is slow, asymptomatic and may lead to sudden cardiac arrest, stroke or myocardial infraction.
arxiv   +1 more source

A prospective natural-history study of coronary atherosclerosis.

New England Journal of Medicine, 2011
BACKGROUND Atherosclerotic plaques that lead to acute coronary syndromes often occur at sites of angiographically mild coronary-artery stenosis. Lesion-related risk factors for such events are poorly understood.
G. Stone, A. Maehara, A. Lansky, B. de Bruyne, Ecaterina Cristea, G. Mintz, R. Mehran, J. Mcpherson, Naim Z. Farhat, S. Marso, H. Parise, B. Templin, Roseann M. White, Zhen Zhang, P. Serruys   +14 more
semanticscholar   +1 more source

An automatic deep learning approach for coronary artery calcium segmentation [PDF]

EMBEC & NBC 2017. IFMBE, volume 65, pp. 374-377, 2017
Coronary artery calcium (CAC) is a significant marker of atherosclerosis and cardiovascular events. In this work we present a system for the automatic quantification of calcium score in ECG-triggered non-contrast enhanced cardiac computed tomography (CT) images. The proposed system uses a supervised deep learning algorithm, i.e.
arxiv   +1 more source

Inflammation, atherosclerosis, and coronary artery disease.

New England Journal of Medicine, 2005
ecent research has shown that inflammation plays a key role in coronary artery disease (CAD) and other manifestations of atherosclerosis. Immune cells dominate early atherosclerotic lesions, their effector molecules accelerate progression of the lesions,
G. Hansson
semanticscholar   +1 more source

Inflammation, Atherosclerosis and Coronary Artery Disease

Clinical Medicine Insights: Cardiology, 2014
Article types include original clinical and basic research articles, case reports, commentaries, meeting reports, methodology, perspectives. Research into inflammation, atherosclerosis and coronary artery disease, including observational studies ...
Y. Momiyama, H. Adachi, D. Fairweather, N. Ishizaka, Emi Saita   +4 more
semanticscholar   +1 more source

Infectious agents in coronary atherosclerosis [PDF]

Arquivos Brasileiros de Cardiologia, 1999
In 1908, Sir William Osler was the first to suggest that infection might play a role in the pathogenesis of atherosclerosis . Even though this view was not widely accepted originally, a renewed interest currently abounds regarding the contribution of infection to the pathogenesis and progression of ischemic heart disease.
Silva Neto, Luís Beck da, Ribeiro, Jorge Pinto   +1 more
openaire   +5 more sources

Long‐term outcomes after paclitaxel‐coated balloon angioplasty of femoropopliteal arteries in Asian patients of the IN.PACT Global Study

Catheterization and Cardiovascular Interventions, Volume 100, Issue 7, Page 1273-1283, December 1, 2022., 2022
Abstract Objectives The long‐term data on the use of drug‐coated balloons (DCBs) for femoropopliteal atherosclerotic lesions in the real‐world setting are limited, even more so for racially and geographically distinct populations. The present analysis reports the 5‐year safety and effectiveness outcomes of a DCB in the Asian subset of the prospective ...
Young‐Guk Ko, Donghoon Choi, Seung‐Woon Rha, Je Hwan Won, Young‐Soo Do, Seung‐Whan Lee, Jeremiah S. Menk, Steven Kum   +7 more
wiley   +1 more source

Calcification and atherosclerosis of the coronary arteries

Terapevticheskii arkhiv, 2021
Calcification is a very common phenomenon in the coronary arteries, which is part of the atherosclerotic process, and the degree of calcification can predict clinical outcomes in patients at high risk of coronary events. Both the degree of calcification and the patterns of its distribution are of prognostic importance, but the relationship of coronary ...
Elena V. Kashtanova, Yana V. Polonskaya, Yulia I. Ragino   +2 more
openaire   +5 more sources