Results 311 to 320 of about 1,303,190 (334)

Imperative for a health‐centred focus on climate change in radiology

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Summary Climate change negatively impacts individual and population‐level health through multiple pathways, including poor air quality, extreme heat and changes in infectious disease. These health effects will lead to higher health system and medical imaging utilisation.
Omar Taboun, Chloe DesRoche, Kate Hanneman   +2 more
wiley   +1 more source

Lactate Secretion by Monocytes as a Determinant of Innate Immune Cell Fitness in Healthy Elderly

Aging Cell, EarlyView.
Lactate secretion by monocytes can be used to classify healthy elderly individuals with reduced immune fitness exemplified by hypermetabolic and hyperinflammatory responses. This classification may reflect increased susceptibility to cardiometabolic complications given its link with higher circulating LDL‐c and VEGF levels.
Lisa Smeehuijzen, Frank Vrieling, Jenny Jansen, Hendrik J. P. van der Zande, Thomas M. Houslay, Gabriele Gross, Janna A. van Diepen, Lydia A. Afman, Rinke Stienstra   +8 more
wiley   +1 more source

The causal relationship between 233 metabolites and coronary atherosclerosis: a Mendelian randomization study. [PDF]

Front Cardiovasc Med
Zhang H, Zheng X, Yan Z, Guo L, Zheng Y, Zhang D, Ma X.   +6 more
europepmc   +1 more source

First Direct Evidence of Accelerated Molecular Aging in Intracranial Aneurysmal Tissue

Aging Cell, EarlyView.
This study provides the first direct evidence of accelerated molecular aging in human intracranial aneurysm tissue, marked by telomere shortening, oxidative DNA damage, and activation of mTOR and NF‐κB pathways. These findings reveal critical aging‐related mechanisms potentially driving aneurysm formation and rupture.
Dilaware Khan, Xuanchen Li, Michael Hewera, Sajjad Muhammad   +3 more
wiley   +1 more source

Dissecting Causal Relationship Among Immune Cells, Plasma Metabolites and Coronary Atherosclerosis: A Mendelian Randomization Study. [PDF]

Immunotargets Ther
Cao Q, Liu J, Sun J, Qian S, Song J, Zheng H, Wen J, Zheng B.   +7 more
europepmc   +1 more source

Association of Epigenetic Age Acceleration and Mitochondrial DNA‐Based Aging Metrics Provides Insights Into Mechanisms of Aging‐Related Diseases

Aging Cell, EarlyView.
Older participants exhibit lower mtDNA copy number (CN) and a higher rare heteroplasmy burden, while common heteroplasmy burden remains relatively stable. Higher epigenetic age acceleration is associated with lower mtDNA CN and higher rare heteroplasmy burden in 6316 participants.
Mengyao Wang, Yinan Zheng, Meng Lai, Emmanuel Saake, Xue Liu, Xiuqing Guo, Kent D. Taylor, Tianxiao Huan, Roby Joehanes, Drew R. Nannini, Kai Zhang, Nicole J. Lake, Christina A. Castellani, Stephen S. Rich, Jerome I. Rotter, Yongmei Liu, Laura M. Raffield, April P. Carson, Myriam Fornage, Jiantao Ma, Dan E. Arking, Lifang Hou, Daniel Levy, Chunyu Liu   +23 more
wiley   +1 more source

Elucidating the role of KCTD10 in coronary atherosclerosis: Harnessing bioinformatics and machine learning to advance understanding. [PDF]

Sci Rep
Hu X, Liang F, Zheng M, Xie J, Wang S.
europepmc   +1 more source

Clinical Value and Potential Molecular Mechanism of miR-373-3p in Coronary Atherosclerosis. [PDF]

Clin Appl Thromb Hemost
Shen J, Tang L, Wang Z, Ma Q, Lin F, Liu H.   +5 more
europepmc   +1 more source

Causal effects of circulating immune cells on coronary atherosclerosis: Evidence from Mendelian randomization. [PDF]

Medicine (Baltimore)
Yang X, Yu Y, Hu G, Bai S, Wu J, Guo C.
europepmc   +1 more source

Exercise-Induced Changes in Hemodynamics, Hormones, Electrolytes, and Inflammatory Markers in Veteran Athletes with and without Coronary Atherosclerosis. [PDF]

Med Sci Sports Exerc
Janssen SLJE, Aengevaeren VL, DE Vries F, Kleinnibbelink G, Mingels AMA, Hopman MTE, Mosterd A, Velthuis BK, Riksen NP, Eijsvogels TMH.   +9 more
europepmc   +1 more source