Results 41 to 50 of about 1,113,564 (363)

Circulating miRNAs Are Associated with the Systemic Extent of Atherosclerosis: Novel Observations for miR-27b and miR-146

open access: yesDiagnostics, 2021
The mechanisms that regulate the systemic extent of atherosclerosis are not fully understood. We investigated whether the expression of circulating miRNAs is associated with the extent of stable atherosclerosis to a single territory or multiple ...
Tiago Pereira-da-Silva   +8 more
doaj   +1 more source

Inverse uncertainty quantification of a mechanical model of arterial tissue with surrogate modeling [PDF]

open access: yesarXiv, 2022
Disorders of coronary arteries lead to severe health problems such as atherosclerosis, angina, heart attack and even death. Considering the clinical significance of coronary arteries, an efficient computational model is a vital step towards tissue engineering, enhancing the research of coronary diseases and developing medical treatment and ...
arxiv  

Quantification of Coronary Atherosclerosis in the Assessment of Coronary Artery Disease

open access: yesCirculation Cardiovascular Imaging, 2018
Background: Diagnosis of coronary artery disease and management strategies have relied solely on the presence of diameter stenosis ≥50%. We assessed whether direct quantification of plaque burden (PB) and plaque characteristics assessed by coronary ...
Sang-Eun Lee   +30 more
semanticscholar   +1 more source

Diagnostic value of chaperone activity of heat shock proteins 70 in coronary atherosclerosis [PDF]

open access: yesКардиоСоматика, 2019
Aim. The aim of the research was to study the role of chaperone activity heat shock proteins (HSP) 70 in pathogenesis and diagnostic in patients with coronary atherosclerosis. Materials and methods.
Julia A. Kotova   +2 more
doaj   +1 more source

Perivascular adipose tissue and coronary atherosclerosis

open access: yesHeart, 2018
Adipose tissue (AT) is no longer viewed as a passive, energy-storing depot, and a growing body of evidence supports the concept that both quantitative and qualitative aspects of AT are critical in determining an individual’s cardiometabolic risk profile.
J. Mancio, E. Oikonomou, C. Antoniades
semanticscholar   +1 more source

Semiparametric zero-inflated modeling in multi-ethnic study of atherosclerosis (MESA) [PDF]

open access: yesAnnals of Applied Statistics 2012, Vol. 6, No. 3, 1236-1255, 2012
We analyze the Agatston score of coronary artery calcium (CAC) from the Multi-Ethnic Study of Atherosclerosis (MESA) using the semiparametric zero-inflated modeling approach, where the observed CAC scores from this cohort consist of high frequency of zeroes and continuously distributed positive values.
arxiv   +1 more source

Pathogenesis of atherosclerosis in the tunica intima, media, and adventitia of coronary arteries: An updated review

open access: yesBosnian Journal of Basic Medical Sciences, 2019
Atherosclerosis is a chronic inflammatory disease of arteries and it affects the structure and function of all three layers of the coronary artery wall. Current theories suggest that the dysfunction of endothelial cells is one of the initial steps in the
A. Milutinović   +2 more
semanticscholar   +1 more source

Cerebral autoregulation in patients with acute lacunar infarction: a reliable predictor of outcome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Objective To further investigate the association between dynamic cerebral autoregulation (dCA) and the outcomes in patients with acute lacunar infarction. Methods Patients were prospectively and consecutively enrolled at The First Hospital of Jilin University between 2016 and 2023. dCA was monitored at 1–3 and 7–10 days after the stroke.
Xiang‐Kun Si   +7 more
wiley   +1 more source

Medial Injury/Dysfunction Induced Granulation Tissue Repair is the Pathogenesis of Atherosclerosis [PDF]

open access: yesarXiv, 2020
Atherosclerosis, a chronic lesion of vascular wall, remains a leading cause of death and loss of life years. Classical hypotheses for atherosclerosis are long-standing mainly to explain atherogenesis. Unfortunately, these hypotheses may not explain the variation in the susceptibility to atherosclerosis.
arxiv  

Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease

open access: yesEuropean Heart Journal, 2019
Aims To characterize serum metabolic signatures associated with atherosclerosis in the coronary or carotid arteries and subsequently their association with incident cardiovascular disease (CVD). Methods and results We used untargeted one-dimensional (1D)
I. Tzoulaki   +31 more
semanticscholar   +1 more source

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