Results 41 to 50 of about 1,285,317 (373)

Circulating miRNAs Are Associated with the Systemic Extent of Atherosclerosis: Novel Observations for miR-27b and miR-146

Diagnostics, 2021
The mechanisms that regulate the systemic extent of atherosclerosis are not fully understood. We investigated whether the expression of circulating miRNAs is associated with the extent of stable atherosclerosis to a single territory or multiple ...
Tiago Pereira-da-Silva, Patrícia Napoleão, Marina C. Costa, André F. Gabriel, Mafalda Selas, Filipa Silva, Francisco J. Enguita, Rui Cruz Ferreira, Miguel Mota Carmo   +8 more
doaj   +1 more source

Quantification of Coronary Atherosclerosis in the Assessment of Coronary Artery Disease

Circulation Cardiovascular Imaging, 2018
Background: Diagnosis of coronary artery disease and management strategies have relied solely on the presence of diameter stenosis ≥50%. We assessed whether direct quantification of plaque burden (PB) and plaque characteristics assessed by coronary ...
Sang-Eun Lee, J. Sung, A. Rizvi, F. Lin, Amit Kumar, M. Hadamitzky, Yong‐Jin Kim, E. Conte, D. Andreini, G. Pontone, M. Budoff, I. Gottlieb, Byoung‐Kwon Lee, E. Chun, Filippo Cademartiri, E. Maffei, H. Marques, J. Leipsic, Sanghoon Shin, Jung Hyun Choi, K. Chinnaiyan, G. Raff, R. Virmani, H. Samady, P. Stone, D. Berman, J. Narula, L. Shaw, Jeroen J. Bax, J. Min, H. Chang   +30 more
semanticscholar   +1 more source

Diagnostic value of chaperone activity of heat shock proteins 70 in coronary atherosclerosis [PDF]

КардиоСоматика, 2019
Aim. The aim of the research was to study the role of chaperone activity heat shock proteins (HSP) 70 in pathogenesis and diagnostic in patients with coronary atherosclerosis. Materials and methods.
Julia A. Kotova, Anna A. Zuikova, Alexander N. Pashkov   +2 more
doaj   +1 more source

Progression of Coronary Artery Calcium and Incident Heart Failure: The Multi-Ethnic Study of Atherosclerosis. [PDF]

, 2017
BackgroundAlthough the association between coronary artery calcium (CAC) and future heart failure (HF) has been shown previously, the value of CAC progression in the prediction of HF has not been investigated.
Ambale-Venkatesh, Bharath, Bahrami, Hossein, Bakhshi, Hooman, Bluemke, David A, Budoff, Matthew, Lima, João AC, Ostovaneh, Mohammad R, Wong, Nathan D, Wu, Colin O, Yang, Xiaoying   +9 more
core   +2 more sources

Serum Trimethylamine-N-Oxide is Elevated in CKD and Correlates with Coronary Atherosclerosis Burden.

Journal of the American Society of Nephrology, 2016
Trimethlyamine-N-oxide (TMAO) was recently identified as a promoter of atherosclerosis. Patients with CKD exhibit accelerated development of atherosclerosis; however, no studies have explored the relationship between TMAO and atherosclerosis formation in
Jason R. Stubbs, J. House, A. Ocque, Shiqin Zhang, Cassandra Johnson, Cassandra Kimber, Kyle Schmidt, Aditi Gupta, J. Wetmore, T. Nolin, J. Spertus, A. Yu   +11 more
semanticscholar   +1 more source

Impaired aortic distensibility measured by computed tomography is associated with the severity of coronary artery disease. [PDF]

, 2010
Impaired aortic distensibility index (ADI) is associated with cardiovascular risk factors. This study evaluates the relation of ADI measured by computed tomographic angiography (CTA) with the severity of coronary atherosclerosis in subjects with ...
Ahmadi, Naser, Azmoon, Shahdad, Budoff, Matthew J, Ebrahimi, Ramin, Flores, Ferdinand, Hajsadeghi, Fereshteh, Ismaeel, Hussain, Mao, Song S, Nabavi, Vahid, Shavelle, David   +9 more
core   +3 more sources

Perivascular adipose tissue and coronary atherosclerosis

Heart, 2018
Adipose tissue (AT) is no longer viewed as a passive, energy-storing depot, and a growing body of evidence supports the concept that both quantitative and qualitative aspects of AT are critical in determining an individual’s cardiometabolic risk profile.
J. Mancio, E. Oikonomou, C. Antoniades
semanticscholar   +1 more source

Is there a role for thoracic aortic calcium to fine-tune cardiovascular risk prediction? [PDF]

, 2012
Screening asymptomatic subjects to streamline measures for the prevention of cardiovascular events remains a major challenge. The established primary prevention risk-scoring methods use equations derived from large prospective cohort studies, but further
Birgelen, C. von, Hartmann, M.
core   +3 more sources

Diabetes mellitus and ischemic heart disease. the role of ion channels [PDF]

, 2018
Diabetes mellitus is one the strongest risk factors for cardiovascular disease and, in particular, for ischemic heart disease (IHD). The pathophysiology of myocardial ischemia in diabetic patients is complex and not fully understood: some diabetic ...
De Marchis, Marialaura, D’Amato, Andrea, Fedele, Francesco, Mancone, Massimo, Netti, Lucrezia, Palmirotta, Raffaele, Pucci, Mariateresa, Severino, Paolo, Volterrani, Maurizio   +8 more
core   +2 more sources

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source