Results 41 to 50 of about 1,299,216 (376)

Atherothrombosis and Oxidative Stress: Mechanisms and Management in Elderly [PDF]

, 2017
Significance: The incidence of cardiovascular events (CVEs) increases with age, representing the main cause of death in an elderly population. Aging is associated with overproduction of reactive oxygen species (ROS), which may affect clotting and ...
Carnevale, Roberto, Loffredo, Lorenzo, Pastori, Daniele, Pignatelli, Pasquale, Violi, Francesco   +4 more
core   +1 more source

Neutrophil subsets and their gene signature associate with vascular inflammation and coronary atherosclerosis in lupus.

JCI Insight, 2018
BACKGROUND Systemic lupus erythematosus (SLE) is associated with enhanced risk of atherosclerotic cardiovascular disease not explained by Framingham risk score (FRS).
P. Carlucci, M. Purmalek, A. Dey, Yenealem Temesgen-Oyelakin, Simantini Sakhardande, A. Joshi, J. Lerman, Alice Fike, M. Davis, Jonathan H. Chung, M. Playford, Mohammad Naqi, Pragnesh Mistry, G. Gutierrez-Cruz, S. Dell’Orso, Faiza Naz, Taufiq Salahuddin, B. Natarajan, Z. Manna, W. Tsai, Sarthak Gupta, P. Grayson, H. Teague, Marcus Y. Chen, Hong-Wei Sun, S. Hasni, N. Mehta, M. Kaplan   +27 more
semanticscholar   +1 more source

Circulating miRNAs Are Associated with the Systemic Extent of Atherosclerosis: Novel Observations for miR-27b and miR-146

Diagnostics, 2021
The mechanisms that regulate the systemic extent of atherosclerosis are not fully understood. We investigated whether the expression of circulating miRNAs is associated with the extent of stable atherosclerosis to a single territory or multiple ...
Tiago Pereira-da-Silva, Patrícia Napoleão, Marina C. Costa, André F. Gabriel, Mafalda Selas, Filipa Silva, Francisco J. Enguita, Rui Cruz Ferreira, Miguel Mota Carmo   +8 more
doaj   +1 more source

Carotid intima media thickness and low high-density lipoprotein (HDL) in South Asian immigrants: could dysfunctional HDL be the missing link? [PDF]

, 2014
IntroductionSouth Asian immigrants (SAIs) in the US exhibit higher prevalence of coronary artery disease (CAD) and its risk factors compared with other ethnic populations.
Dodani, Sunita, Dong, Lei, Guirgis, Faheem W, Reddy, Srinivasa T   +3 more
core   +2 more sources

Diagnostic value of chaperone activity of heat shock proteins 70 in coronary atherosclerosis [PDF]

КардиоСоматика, 2019
Aim. The aim of the research was to study the role of chaperone activity heat shock proteins (HSP) 70 in pathogenesis and diagnostic in patients with coronary atherosclerosis. Materials and methods.
Julia A. Kotova, Anna A. Zuikova, Alexander N. Pashkov   +2 more
doaj   +1 more source

Association of Genetically Predicted Lipid Levels With the Extent of Coronary Atherosclerosis in Icelandic Adults

JAMA cardiology, 2019
Key Points Question Are genetically predicted lipid levels associated with the extent of coronary atherosclerosis? Findings This study found that a genetic score for non–high-density lipoprotein cholesterol was significantly associated with the extent of
Eythór Björnsson, G. Thorleifsson, A. Helgadóttir, Thórarinn Guðnason, Tómas Guðbjartsson, K. Andersen, S. Gretarsdottir, I. Olafsson, V. Tragante, O. Olafsson, B. Jónsdóttir, G. Eyjolfsson, Ólöf Sigurðardóttir, G. Thorgeirsson, Daníel F. Guðbjartsson, U. Thorsteinsdóttir, H. Hólm, K. Stefánsson   +17 more
semanticscholar   +1 more source

Quantification of atherosclerotic plaque volume in coronary arteries by computed tomographic angiography in subjects with and without diabetes. [PDF]

, 2020
BackgroundDiabetes mellitus (DM) is considered a cardiovascular risk factor. The aim of this study was to analyze the prevalence and volume of coronary artery plaque in patients with diabetes mellitus (DM) vs. those without DM.MethodsThis study recruited
An, Yun-Qiang, Budoff, Matthew J, Gao, Yang, Hou, Zhi-Hui, Li, Zhen-Nan, Lu, Bin, Yin, Wei-Hua   +6 more
core   +1 more source

Computational Modelling of Atherosclerosis

, 2015
Atherosclerosis is one of the principle pathologies of cardiovascular disease with blood cholesterol a significant risk factor. The World Health Organisation estimates that approximately 2.5 million deaths occur annually due to the risk from elevated ...
Baldrick, Francina R, McGilligan, Victoria, OKane, Maurice, Parton, Andrew, Watterson, Steven   +4 more
core   +1 more source

Independent and joint effects of antibodies to human heat-shock protein 60 and Chlamydia pneumoniae infection in the development of coronary atherosclerosis [PDF]

, 2001
Background—Studies have suggested that the prevalence of antibodies against heat-shock proteins (HSPs), Chlamydia pneumoniae (Cpn), and cytomegalovirus (CMV) is associated with coronary artery disease (CAD), but the independent or joint effects of ...
Berencsi, Klára, Boda, Krisztina, Burián, Katalin, Duba, Jenő, Endrész, Valéria, Füst, György, Gönczöl, Éva, Horváth, Laura, Kis, Zoltán, Prohászka, Zoltán, Romics, László, Virók, Dezső   +11 more
core   +1 more source

Quantification of Coronary Atherosclerosis in the Assessment of Coronary Artery Disease

Circulation Cardiovascular Imaging, 2018
Background: Diagnosis of coronary artery disease and management strategies have relied solely on the presence of diameter stenosis ≥50%. We assessed whether direct quantification of plaque burden (PB) and plaque characteristics assessed by coronary ...
Sang-Eun Lee, J. Sung, A. Rizvi, F. Lin, Amit Kumar, M. Hadamitzky, Yong‐Jin Kim, E. Conte, D. Andreini, G. Pontone, M. Budoff, I. Gottlieb, Byoung‐Kwon Lee, E. Chun, Filippo Cademartiri, E. Maffei, H. Marques, J. Leipsic, Sanghoon Shin, Jung Hyun Choi, K. Chinnaiyan, G. Raff, R. Virmani, H. Samady, P. Stone, D. Berman, J. Narula, L. Shaw, Jeroen J. Bax, J. Min, H. Chang   +30 more
semanticscholar   +1 more source