Results 51 to 60 of about 175,633 (246)

Endothelial Cell‐Specific Molecule‐1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis

Advanced Science, EarlyView.
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen, Xiaojuan Ge, Dongxu Fu, Haijun Mei, Feng Lv, Chao Yang, Jiahao Lu, Xiaozhong Shen, Bowen Li, Xiaoning Wang, Dong Liu   +10 more
wiley   +1 more source

Epidemiologic study of patients with DVT in Birjand Vali-e-asr hospital- (2009-2014): Short Communication

مجله دانشگاه علوم پزشکی بیرجند, 2016
Background and Aim: Deep vein thrombosis (DVT) is a condition that, in case of delay in diagnosis and treatment, can lead to serious complications like pulmonary embolism.
Toba Kazemi, Mahsa Qasemi, Mohsen Taghavi-shawazi   +2 more
doaj  

The Role of Interventional Cardiology to Our Understanding of Basic Mechanisms Related to Coronary Atherosclerosis: “Thinking outside the box”

Hellenic Journal of Cardiology, 2017
Interventional cardiology has contributed significantly to our understanding of coronary atherosclerosis. Interventional cardiology has allowed a correlation between the clinical picture of coronary atherosclerosis with the underlying pathology and has ...
Konstantinos Dean Boudoulas, MD, Christodoulos Stefanadis, MD, Harisios Boudoulas, MD, Dr., Dr. Hon   +2 more
doaj   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source

Intact Pleura during Left Internal Mammary Artery Harvesting in a Patient with kyphoscoliosis and Chronic Obstructive Pulmonary Disease

Journal of Tehran University Heart Center, 2015
Letter to the ...
Mahmood Hosseinzadeh-Maleki, Toba Kazemi, HamidReza Mashraghi-Moghaddam   +2 more
doaj  

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Approach to Chronic Secondary Headache: A Case Report on Unusual Drug Side Effects

Iranian Journal of Medical Sciences, 2017
In this article, we present the case of a 12-year-old female child who complained of bilateral temporal and frontal headache for 2 to 3 months with nausea and vomiting.
Hamid Reza Riasi, Forod Salehi, Morteza Hajihosseini   +2 more
doaj  

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

Advanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang, Xiangheng Cai, Mengqi Li, Xue Liu, Junhui Xue, Ye Liu, Ding Ai, Xinyang Hu   +7 more
wiley   +1 more source

Prevalence and risk factors for abdominal aortic aneurysm in people over 65 years old who referred to the ultrasound centers of educational hospitals in Birjand in 2014

مجله دانشگاه علوم پزشکی بیرجند, 2015
Background and Aim: Abdominal aortic aneurysm is an important mortality factor especially in old men. The present study aimed at investigating prevalence of abdominal aortic aneurysm in people over 65 years old who referred to the ultrasonic centers in ...
Mahyar Mohamadifard, Alireza Mamashli, Toba Kazemi   +2 more
doaj  

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source