Results 51 to 60 of about 1,284,948 (376)

Perivascular adipose tissue and coronary atherosclerosis

Heart, 2018
Adipose tissue (AT) is no longer viewed as a passive, energy-storing depot, and a growing body of evidence supports the concept that both quantitative and qualitative aspects of AT are critical in determining an individual’s cardiometabolic risk profile.
J. Mancio, E. Oikonomou, C. Antoniades
semanticscholar   +1 more source

Risk Factors for Long-Term Coronary Artery Calcium Progression in the Multi-Ethnic Study of Atherosclerosis. [PDF]

, 2015
BackgroundCoronary artery calcium (CAC) detected by noncontrast cardiac computed tomography scanning is a measure of coronary atherosclerosis burden. Increasing CAC levels have been strongly associated with increased coronary events.
Blaha, Michael J, Budoff, Matthew, Gassett, Amanda J, Kaufman, Joel D, Kronmal, Richard, McClelland, Robyn L, Olives, Casey, Sheppard, Lianne   +7 more
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Targeting inflammation to reduce cardiovascular disease risk: a realistic clinical prospect? [PDF]

, 2017
Data from basic science experiments is overwhelmingly supportive of the causal role of immune-inflammatory response(s) at the core of atherosclerosis, and therefore the theoretical potential to manipulate the inflammatory response to prevent ...
Abbas, Agca, Ait-Oufella, Albert, Alexander, Alexander, Alexander, Alexander, Andersen, Aziz, Babelova, Bellosta, Bevilacqua, Bhaskar, Blom, Boekholdt, Boekholdt, Bostrom, Brånén, Bulgarelli, Bulgarelli, Burke, Cai, Cannon, Casas, Collins, Cronstein, Dahlman-Ghozlan, Danesh, Davenport, Davey Smith, Davidson, DeOliveira, Devlin, Dinarello, Duewell, Duivenvoorden, Eisenhardt, Elango, Elhage, Ettehad, Flood, Fraser, Freigang, Fulgoni, Galkina, Galkina, Garlanda, Grassia, Grassia, Greenberg, Hansson, Hauer, Herder, Holmes, Hu, Huang, Huber, Interleukin 1 Genetics Consortium, Ivandic, Kalliolias, Kaptoge, Kimura, Kinlay, Kirii, Kleinman, Koltsova, Kureishi, Kwak, Lee, Leite, Leite, Lewington, Liao, Libby, Libby, Macritchie, Maddaluno, Maeda, Maffia, Makheja, Margaritis, McInnes, Menu, Micha, Mihaylova, Mira, Mohler, Montezano, Mulhaupt, Murad, Myasoedova, Myung, Nakata, Nicholls, O'Donoghue, Ogdie, Ohta, Pauling, Peters, Qiao, Quarck, Rajamäki, Rastogi, Reiss, Rezaie-Majd, Ridker, Ridker, Rincón, Robertson, Romano, Rosenson, Rosenson, Roubille, Ryan, Rössig, Saeed, Sage, Sarwar, Sattar, Scalia, Schett, Schieffer, Schuett, Serruys, Sever, Sever, Shah, Shaposhnik, Singh, Sirtori, Sniderman, Soedamah-Muthu, Solomon, Southan, Souverein, Sprague, Srikakulapu, Strober, Sukovich, Swerdlow, Swirski, Talmud, Tay, Teng, Thompson, Tits, Toedter, Turunen, Tzellos, Walker, Wang, Wang, Watson, Weintraub, Welsh, Welsh, Welsh, Welsh, Weng, Wensley, White, Wilensky, Willeit, Willis, Wong, Woodward, Xanthoulea, Ye, Ye, Yilmaz, Youssef, Zalewski, Zhao   +173 more
core   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source

Analysis of the causes of repeat stenosis of the coronary arteries after elective stenting in patients with stable angina pectoris

Терапевтический архив, 2021
Aim. Coronary stenting is the evidence-based treatment approach of stable angina. The objective was to determine the incidence of restenosis or atherosclerosis progression which led to the need for coronary angiography according to a single center ...
Anastasia Y. Filatova, Anna K. Osokina, Alexandra V. Potekhina, Ivan V. Romasov, Tatiana I. Kotkina, Alexandra M. Shchinova, Elena A. Noeva, Tatiana I. Arefieva, Elena A. Barabanova, Evgeny V. Merkulov, Anatoly N. Samko, Sergey I. Provatorov   +11 more
doaj   +1 more source

Pathogenesis of atherosclerosis in the tunica intima, media, and adventitia of coronary arteries: An updated review

Bosnian Journal of Basic Medical Sciences, 2019
Atherosclerosis is a chronic inflammatory disease of arteries and it affects the structure and function of all three layers of the coronary artery wall. Current theories suggest that the dysfunction of endothelial cells is one of the initial steps in the
A. Milutinović, D. Šuput, R. Zorc-Pleskovič   +2 more
semanticscholar   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Travel Diarrhea in Childhood, “Part Two; what is the Problem?”

International Journal of Travel Medicine and Global Health, 2016
In the first part, we briefly reviewed literature about the characteristics, etiology, pathology, and management of pediatric travel diarrhea (TD). Ultimately, we concluded that more studies are needed on its pathogenesis, pathogen frequency, prevention,
Fatemeh Eghbal, Amin Saburi
doaj   +1 more source

Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease

European Heart Journal, 2019
Aims To characterize serum metabolic signatures associated with atherosclerosis in the coronary or carotid arteries and subsequently their association with incident cardiovascular disease (CVD). Methods and results We used untargeted one-dimensional (1D)
I. Tzoulaki, R. Castagné, C. Boulangé, I. Karaman, E. Chekmeneva, E. Evangelou, T. Ebbels, M. Kaluarachchi, M. Chadeau-Hyam, D. Mosen, A. Dehghan, A. Moayyeri, D. L. S. Ferreira, Xiuqing Guo, J. Rotter, K. Taylor, M. Kavousi, P. D. de Vries, B. Lehne, M. Loh, A. Hofman, J. Nicholson, J. Chambers, C. Gieger, E. Holmes, R. Tracy, J. Kooner, P. Greenland, O. Franco, D. Herrington, J. Lindon, P. Elliott   +31 more
semanticscholar   +1 more source