Impaired coronary blood flow at higher heart rates during atrial fibrillation: investigation via multiscale modelling [PDF]
Computer Methods and Programs in Biomedicine, 175: 95-102, 2019, 2019 Background. Different mechanisms have been proposed to relate atrial fibrillation (AF) and coronary flow impairment, even in absence of relevant coronary artery disease (CAD). However, the underlying hemodynamics remains unclear. Aim of the present work is to computationally explore whether and to what extent ventricular rate during AF affects the ...
Anselmino, Matteo +4 more
arxiv +5 more sources
The coronary circulation in acute myocardial ischaemia/reperfusion injury: a target for cardioprotection. [PDF]
Cardiovasc Res, 2019 The coronary circulation is both culprit and victim of acute myocardial infarction. The rupture of an epicardial atherosclerotic plaque with superimposed thrombosis causes coronary occlusion, and this occlusion must be removed to induce reperfusion ...
Hausenloy DJ +8 more
europepmc +2 more sources
A patient-specific lumped-parameter model of coronary circulation. [PDF]
Sci Rep, 2018 A new lumped-parameter model for coronary hemodynamics is developed. This model is developed for the whole coronary network based on CT scans of a patient-specific geometry including the right coronary tree, which is absent in many previous mathematical ...
Duanmu Z, Yin M, Fan X, Yang X, Luo X.
europepmc +2 more sources
Wave intensity analysis and its application to the coronary circulation. [PDF]
Glob Cardiol Sci Pract, 2017 Wave intensity analysis (WIA) is a technique developed from the field of gas dynamics that is now being applied to assess cardiovascular physiology. It allows quantification of the forces acting to alter flow and pressure within a fluid system, and as ...
Broyd CJ +4 more
europepmc +2 more sources
A review of multiscale 0D–1D computational modeling of coronary circulation with applications to cardiac arrhythmias [PDF]
Reviews in Cardiovascular Medicine, 2021 Computational hemodynamics is becoming an increasingly important tool in clinical applications and surgical procedures involving the cardiovascular system.
Stefania Scarsoglio +1 more
doaj +2 more sources
Effects of atorvastatin and rosuvastatin on dysfunctional coronary circulation in patients with ST-segment elevation myocardial infarction [PDF]
Journal of International Medical Research, 2023 Objective Evidence of therapy for dysfunctional coronary circulation in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI) is limited.
Langping Zhou +10 more
doaj +2 more sources
The Coronary Circulation as a Target of Cardioprotection [PDF]
Circulation Research, 2016 The atherosclerotic coronary vasculature is not only the culprit but also a victim of myocardial ischemia/reperfusion injury. Manifestations of such injury are increased vascular permeability and edema, endothelial dysfunction and impaired vasomotion, microembolization of atherothrombotic debris, stasis with intravascular cell aggregates, and finally ...
G. Heusch
openaire +5 more sources
THE ACTION OF THE NITRITES ON THE CORONARY CIRCULATION [PDF]
Archives of Internal Medicine, 1921 The nitrites have been employed in the treatment of angina pectoris since the time of Lauder Brunton, and it is well known that in many instances the pain subsides soon after the administration of a pearl of amyl nitrite or a pellet of nitroglycerin.
F. Smith
openaire +4 more sources
Relation between Preinfarction Angina and Coronary Collateral Circulation in Patients with Acute Myocardial Infarction [PDF]
Althea Medical Journal, 2016 Background: Coronary collateral circulation conduits an alternative blood flow to the ischemic myocardium in the setting of coronary artery occlusion which can prevent the infarction area to extend more widely.
Achmad Shidiq +2 more
doaj +3 more sources
Measurements of coronary velocity and reactive hyperemia in the coronary circulation of humans. [PDF]
Circulation Research, 1981 An acceptable method for measuring phasic coronary velocity and reactive hyperemia in humans has not been available. We have developed a doppler probe which can be coupled to surface coronary vessel* at the time of cardiac surgery with a small suction ...
Melvin L. Marcus +7 more
openalex +2 more sources