Results 171 to 180 of about 13,767 (259)

Drug‐coated balloons: From conventional designs to next‐generation innovations in vascular therapy

open access: yesBMEMat, EarlyView.
This review traces the evolution of drug‐coated balloons (DCBs) from conventional designs to next‐generation platforms. We highlight innovations in balloon engineering, coating technologies, and therapeutic agents that enhance localized drug delivery while addressing challenges in efficiency, safety, and biocompatibility for vascular and emerging non ...
Lu Zhang   +5 more
wiley   +1 more source

Mimic, target, and adapt: Cell membrane‐coated nanoplatforms for precision and immune‐guided cancer treatment

open access: yesBMEMat, EarlyView.
This Perspective explores the emerging landscape of cell membrane‐coated nanoparticles (CM‐NPs) as intelligent, immune‐compatible platforms for cancer therapy. Highlighting design strategies, translational challenges, and competitive positioning, it outlines how integrating biomimetic targeting with advanced analytical and manufacturing tools could ...
A. K. M. M. Alam   +4 more
wiley   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

open access: yesBMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu   +5 more
wiley   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

open access: yesBMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo   +9 more
wiley   +1 more source

Scalable desolvation synthesis, storage stability, and comprehensive biophysical characterization of human hemoglobin nanoparticles as a potential hemoglobin‐based oxygen carrier

open access: yesBiotechnology Progress, EarlyView.
This work describes the development of human hemoglobin nanoparticles using an anti‐solvent precipitation synthesis method as a potential next generation hemoglobin‐based oxygen carrier. The hemoglobin nanoparticles are uniform in size and shape, hemocompatible, stable at various storage conditions, and demonstrate a scalable synthesis technique ...
Alisyn Greenfield, Andre F. Palmer
wiley   +1 more source

Maximizing Neurovascular Outcomes of Facial Transplantation: A Comprehensive Review

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Facial transplantation is a division of reconstructive surgery which aims to improve the function and appearance of a face that has endured severe disfigurement. Currently, the face transplant procedure uses allogenic tissue, harvested from a brain‐dead donor, to replace damaged facial components.
Olivia A. James, Faye Bennett
wiley   +1 more source

Clinical and Physiological Predictors of Acetylcholine‐Induced Coronary Spasm in ANOCA/INOCA Patients: A Retrospective Cohort Study

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background A substantial proportion of patients with angina and/or ischemia are found to have non‐obstructive coronary arteries (ANOCA/INOCA). Their symptoms can sometimes be explained by coronary microvascular dysfunction and/or vasospasm. Selecting patients for acetylcholine testing remains challenging, and the procedure is not trivial in ...
Jeremie Buri   +7 more
wiley   +1 more source

Unveiling the Microvasculature: The Index of Microcirculatory Resistance and Its Expanding Role in Cardiovascular Care

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Index of microcirculatory resistance (IMR) is a cutting‐edge, wire‐based tool that advances the capability assessment of coronary microvascular function. By utilizing distal coronary pressure and mean transit time under maximal hyperemia, IMR delivers consistent, reproducible insights into the microvasculature's dynamic health.
Joanna Sohn   +10 more
wiley   +1 more source

Echocardiography‐Assisted Stenting of the Ductus Venosus in Infracardiac TAPVC: Report of a New Technique and Review of the Literature

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Neonates with infracardiac total anomalous pulmonary venous connection (TAPVC) frequently require urgent treatment. If surgical repair is contraindicated due to extreme prematurity, interventional stenting of the ductus venosus (DV) has been introduced successfully to postpone surgery.
Simon Schmid   +4 more
wiley   +1 more source

Feasibility and Safety of Distal Transradial Access in Patients With Out‐of‐Hospital Cardiac Arrest Undergoing Emergency PCI: A Single‐Center Retrospective Study

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Distal transradial access (dTRA) has gained attention for its lower risk of vascular complications compared to conventional transradial access (TRA). However, its feasibility and safety in patients with out‐of‐hospital cardiac arrest (OHCA) undergoing emergency percutaneous coronary intervention (PCI) remain uncertain.
Shiori Kawakami   +9 more
wiley   +1 more source

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