Impaired coronary blood flow at higher heart rates during atrial fibrillation: investigation via multiscale modelling [PDF]
Background. Different mechanisms have been proposed to relate atrial fibrillation (AF) and coronary flow impairment, even in absence of relevant coronary artery disease (CAD). However, the underlying hemodynamics remains unclear.
Anselmino, Matteo +4 more
core +2 more sources
Responses to stimulation of coronary and carotid baroreceptors and the coronary chemoreflex at different ventricular distending pressures in anaesthetised dogs [PDF]
Stimulation of left ventricular mechanoreceptors was believed not only to exert important effects on the circulation, but also to influence the responses to baroreceptor reflexes.
Drinkhill, M.J. +2 more
core +1 more source
Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need [PDF]
The diagnostic management of patients with angina pectoris typically centres on the detection of obstructive epicardial CAD, which aligns with evidence-based treatment options that include medical therapy and myocardial revascularisation.
Berry, Colin +2 more
core +1 more source
Experimental study on coronary perfusion with selective brain cooling for direct aortic surgery [PDF]
1. Retrograde coronary perfusion in combination with selective brain cooling by irrigation was investigated in dogs, in comparison with direct coronary artery perfusion. 2.
Hayashi, Naomi
core +1 more source
THE CONDITION OF DISTAL AORTA AFTER PROXIMAL RECONSTRUCTION FOR DISSECTION IN MARFAN SYNDROME
Marfan syndrome is a disease associated with high prevalence of aorta-related morbidity and mortality. Dissections and ruptures of thoracal aorta (ThAo) lead to decreased life duration in persons with Marfan syndrome with mediana at 30 year-old.Aim.
A. M. Chernyavskiy +4 more
doaj +1 more source
Coronary artery endothelial dysfunction is positively correlated with low density lipoprotein and inversely correlated with high density lipoprotein subclass particles measured by nuclear magnetic resonance spectroscopy. [PDF]
OBJECTIVE: The association between cholesterol and endothelial dysfunction remains controversial. We tested the hypothesis that lipoprotein subclasses are associated with coronary endothelial dysfunction.
Abhiram Prasad +42 more
core +1 more source
LONG-TERM RESULTS OF THE VALVE-SAVING SURGERY IN MARFAN SYNDROME PATIENTS
The main causes of mortality and morbidity in Marfan syndrome patients are cardiovascular complications. The Bentall DeBono operation for long time has been a gold standard treatment for this pathology.Aim. To present the obvious benefits of valve-saving
D. S. Khvan +4 more
doaj +1 more source
S-nitrosylation of AMPKγ impairs coronary collateral circulation and disrupts VSMC reprogramming
Collateral circulation is essential for blood resupply to the ischemic heart, which is dictated by the contractile phenotypic restoration of vascular smooth muscle cells (VSMC). Here we investigate whether S-nitrosylation of AMP-activated protein kinase (
Wenwu Bai +17 more
doaj +1 more source
Biomarkers of coronary endothelial health: correlation with invasive measures of collateral function, flow and resistance in chronically occluded coronary arteries and the effect of recanalization [PDF]
Objectives: In the presence of a chronically occluded coronary artery, the collateral circulation matures by a process of arteriogenesis; however, there is considerable variation between individuals in the functional capacity of that collateral network ...
Alamgir, Farquad +6 more
core +2 more sources
Biomarkers in acute coronary syndromes and their role in diabetic patients [PDF]
Diabetic patients with acute coronary syndromes are at high risk for cardiovascular complications but risk stratification in these patients remains challenging.
Christopher Heeschen +5 more
core +1 more source

