Results 21 to 30 of about 132,571 (292)

Association of coronary artery dominance and mortality rate and complications in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention

open access: yesJournal of Research in Medical Sciences, 2020
Background: Percutaneous coronary intervention (PCI) is the treatment of choice for patients with ST-segment elevation myocardial infarction (STEMI). Effect of coronary artery dominance on the patients' outcome following primary PCI (PPCI) is not fully ...
Amir Mikaeilvand   +7 more
doaj   +1 more source

A review of multiscale 0D–1D computational modeling of coronary circulation with applications to cardiac arrhythmias

open access: yesReviews in Cardiovascular Medicine, 2021
Computational hemodynamics is becoming an increasingly important tool in clinical applications and surgical procedures involving the cardiovascular system.
Stefania Scarsoglio   +1 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

The Role of Collateral Circulation in Preserving Myocardial Function

open access: yesBiomolecules & Biomedicine, 2006
The coronary collateral circulation is an alternative source of blood supply to the myocardium jeopardized by the failure of the original stenotic or occluded vessel to provide adequate blood flow to this region. One hundred coronary angiograms and left
Aida Hasanović   +2 more
doaj   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

Reprogramming the myocardial infarction microenvironment with melanin-based composite nanomedicines in mice

open access: yesNature Communications
Myocardial infarction (MI) has a 5-year mortality rate of more than 50% due to the lack of effective treatments. Interactions between cardiomyocytes and the MI microenvironment (MIM) can determine the progression and fate of infarcted myocardial tissue ...
Yamei Liu   +14 more
doaj   +1 more source

Computational Analysis of Haemodynamic Indices in Synthetic Atherosclerotic Coronary Netwroks

open access: yesMathematics, 2021
Haemodynamic indices are widely used in clinical practice when deciding on a particular type of treatment. Low quality of the computed tomography data and tachycardia complicate interpretation of the measured or simulated values. In this work, we present
Sergey Simakov   +3 more
doaj   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry   +2 more
wiley   +1 more source

Association between body fat variation rate and risk of diabetic nephropathy - a posthoc analysis based on ACCORD database

open access: yesBMC Public Health
Background Weight control has consistently been regarded as a significant preventive measure against diabetic nephropathy. however, the potential impact of substantial fluctuations in body fat during this process on the risk of diabetic nephropathy ...
Shuai Li   +6 more
doaj   +1 more source

Computed tomography in cardiology: history and perspectives

open access: yesТерапевтический архив, 2023
The review article highlights the main stages of the formation of computed tomography (CT) as a key method used in modern cardiology. The progress of CT scanners is directly related to the increase in the number of detectors, and thus, with an increase ...
Olga Iu. Mironova   +3 more
doaj   +1 more source

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