Results 191 to 200 of about 10,498,114 (427)
Cubic Phase‐Inducible Zwitterionic Phospholipids Improve the Functional Delivery of mRNA
Advanced Science, EarlyView.In this study, a chemically engineered zwitterionic phospholipids derived from 1,2‐dioleoyl‐3‐sn‐glycero‐phosphoethanolamine (DOPE), DOPE‐Cx, are designed. The DOPE‐Cx lipids induce a cubic phase upon mixing with phosphatidylcholine, facilitate membrane fusion‐mediated endosomal escape, and enhance the functional delivery of mRNA.
Kazuki Iwakawa +5 more
wiley +1 more source
Archiv der Pharmazie, Volume 355, Issue 12, December 2022., 2022 The 18F‐labeled derivative [18F]3 of senicapoc was synthesized using the prosthetic group approach with 1‐azido‐2‐[18F]fluoroethane ([18F]6) in a “click” reaction. The biological activity of the new positron emission tomography tracer was evaluated in vitro and in vivo.
Christian P. Konken +11 more
wiley +1 more source
Advanced Science, EarlyView.Large‐scale studies indicate a strong relationship between the gut microbiome, type 2 diabetes mellitus (T2DM), and atherosclerotic cardiovascular disease (ASCVD). Here, a higher abundance of the type III secretion system (T3SS) virulence factors of Enterobacteriaceae/Escherichia‐Shigella in patients with T2DM‐related‐ASCVD, which correlates with their
Yao‐Yuan Zhang +15 more
wiley +1 more source
Cancer and coronary artery disease among seventh-day adventists [PDF]
, 1959 Ernest L. Wynder +2 more
openalex +1 more source
Advanced Science, EarlyView.Lipid content in medium high‐density lipoprotein (HDL) particles, particularly cholesteryl esters, is identified as causally protective of atherosclerosis, and further ASCVD. Evidence from multi‐omics layers of data consistently supports PSRC1 with therapeutic potential for coronary artery disease (CAD), but not ischemic stroke.
Yingmei Li +8 more
wiley +1 more source
Reviews in Cardiovascular MedicineBackground: Coronary artery calcification (CAC) is a crucial marker for coronary atherosclerosis, and the extent of CAC is closely linked to the incidence and progression of cardiovascular diseases.
Chenyang Wang +9 more
doaj +1 more source
Screening for coronary heart disease [PDF]
, 1990 Malta and the United Kingdom share the dubious distinction of being among the three countries with the highest mortality rate from Cardiovascular disease in Europe; other countries in the Mediterranean basin have much lower rates. This presentation deals
Borg, Anton
core
Geographic Patterns in Deaths from Coronary Heart Disease [PDF]
, 1956 Philip E. Enterline, William H. Stewart
openalex +1 more source
Targeting miRNA‐1a and miRNA‐15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration
Advanced Science, EarlyView.The article explores a novel therapeutic strategy for cardiac regeneration by targeting miRNA‐1a and miRNA‐15b. Combinatorial inhibition of miR‐1a and miR‐15b enhances cardiomyocyte proliferation, improves heart function, and reduces fibrosis in myocardial infarction models.
Ting Yuan +16 more
wiley +1 more source