Results 271 to 280 of about 10,498,114 (427)

In vivo toxic and lethal cardiorespiratory effects of a synthetic quaternary ammonium salt derivative of haloperidol in mice

Animal Models and Experimental Medicine, EarlyView.
Hematoxylin–eosin (H&E) stains of the heart, liver, lung, and kidney show acute toxicity. Abstract Background To investigate the toxicity of N‐n‐butyl haloperidol iodide (F2), a quaternary ammonium salt derivative of haloperidol, in mice for potential therapeutic purposes. Methods The acute median lethal dose (LD50) of F2 was determined using the Bliss
Jilin Liao, Binger Lu, Jinhua Yang, Xiaowan Wang, Shuxian Li, Hongbo Fu, Fenfei Gao   +6 more
wiley   +1 more source

In-stent neoatherosclerosis: a new problem or an opportunity to rethink the treatment of coronary disease? [PDF]

AsiaIntervention
Ussia GP, Cocco N.
europepmc   +1 more source

The etiology of cardiac enlargement in coronary occlusion, hypertension, and coronary artery disease

, 1954
Arthur M. Mastér
openalex   +1 more source

Progress in research on osteoporosis secondary to SARS‐CoV‐2 infection

Animal Models and Experimental Medicine, EarlyView.
This review explores the potential mechanisms, complications, risk factors, and future research directions related to osteoporosis secondary to SARS‐CoV‐2 infection. Key mechanisms include an imbalance between osteoclast and osteoblast activity driven by direct viral effects on bone, inflammation, hypoxia, dysregulation of noncoding RNAs, and metabolic
Jinlong Wang, Yibai Xiong, Zhiqi Song, Yanhong Li, Ling Zhang, Chuan Qin   +5 more
wiley   +1 more source

An Ounce of Prevention for a Pound of Cure?: Lipid-Lowering Therapy for Premature Coronary Disease. [PDF]

JACC Adv
Khurshid S, Kany S.
europepmc   +1 more source

Lecanemab‐Associated Amyloid‐β Protofibril in Cerebrospinal Fluid Correlates with Biomarkers of Neurodegeneration in Alzheimer's Disease

Annals of Neurology, EarlyView.
Objective The Clarity AD phase III trial showed that lecanemab reduced amyloid markers in early Alzheimer's disease (AD) and resulted in less decline on measures of cognition and function than placebo. Herein, we aimed to characterize amyloid‐β (Aβ) protofibril (PF) captured by lecanemab in human cerebrospinal fluid (CSF) from living participants with ...
Moeko Noguchi‐Shinohara, Kazuyoshi Shuta, Hidetomo Murakami, Yukiko Mori, Junji Komatsu, Chizuru Kobayashi, Steven Hersch, Kanta Horie, Kenjiro Ono   +8 more
wiley   +1 more source

Measuring and Targeting Persistent Inflammation in Chronic Coronary Disease. [PDF]

JACC Adv
Frangogiannis NG.
europepmc   +1 more source

SURGICAL TREATMENT OF CORONARY HEART DISEASE

, 1958
ชิน บูรณธรรม
openalex   +2 more sources

The Epidemiology of Coronary Heart Disease—The Framingham Enquiry [PDF]

, 1962
Thomas R. Dawber, William B. Kannel, Nicholas Revotskie, Abraham Kagan   +3 more
openalex   +1 more source

Adult Neurogenesis in the Subventricular Zone of Patients with Huntington's and Parkinson's Diseases and following Long‐Term Treatment with Deep Brain Stimulation

Annals of Neurology, EarlyView.
Objective Parkinson's and Huntington's diseases are characterized by progressive neuronal loss. Previous studies using human postmortem tissues have shown the impact of neurodegenerative disorders on adult neurogenesis. The extent to which adult neural stem cells are activated in the subventricular zone and whether therapeutic treatments such as deep ...
Marta Snapyan, Francis Desmeules, Jonathan Munro, Morgan Bérard, Stephan Saikali, Peter V. Gould, Maxime Richer, Emmanuelle Pourcher, Mélanie Langlois, Anne‐Marie Dufresne, Michel Prud'homme, Léo Cantin, André Parent, Armen Saghatelyan, Martin Parent   +14 more
wiley   +1 more source