Results 281 to 290 of about 1,382,114 (327)

Chronic high‐fat diet induces multi‐organ dysfunction and metabolic homeostasis disruption in Macaca fascicularis

Animal Models and Experimental Medicine, EarlyView.
An 18‐month HFD successfully established a translational Macaca fascicularis model replicating key metabolic disorders (MASH, diabetes, cardiac hypertrophy). MASH was determined by liver biopsy histology, the presence steatosis, inflammatory infiltration, hepatocytic ballooning, and fibrosis were considered as MASH; diabetes was diagnosed according to ...
Hongyi Chen, Wei Liu, Dan Zhou, Shuhua Liu, Yalun Guan, Zongyu Miao, Lei Cai, Xuejiao Li, Yunfeng Li, Zhongqiang Huang, Yi Jin, Ge Li, Yu Zhang   +12 more
wiley   +1 more source

Variation in Health Status With Invasive vs Conservative Management of Chronic Coronary Disease. [PDF]

J Am Coll Cardiol
Arnold SV, Jones PG, Maron DJ, Cohen DJ, Mark DB, Reynolds HR, Bangalore S, Chen J, Newman JD, Harrington RA, Stone GW, Hochman JS, Spertus JA, ISCHEMIA Research Group.   +13 more
europepmc   +1 more source

Establishment of a mouse model of TMAO‐induced cardiac injury and application of MICT intervention

Animal Models and Experimental Medicine, EarlyView.
This study aims to explore the establishment of an animal model of cardiac injury induced by trimethylamine‐N‐oxide (TMAO), a metabolite secreted by gut microorganisms, and to investigate its application in moderate‐intensity continuous training (MICT) intervention.
Zhongping Xie, Hong Zou, Lijing Gong, Minghui Lin, Caihua Huang   +4 more
wiley   +1 more source

Predictive Factors of Unexpected Hospitalization within Six Months of Undergoing Percutaneous Coronary Intervention in Patients with Chronic Coronary Disease. [PDF]

Intern Med
Furukawa T, Mizote I, Shiraki T, Nakamura D, Nishio M, Fukushima N, Kitao T, Yokoi K, Kumada M, Kitagawa M, Nagai K, Kume K, Hirooka K, Nakagawa T, Ohama T, Takahara M, Hikoso S, Sakata Y.   +17 more
europepmc   +1 more source

Disruption of the Blood–Brain Barrier Predicts Progression of Cerebral Small Vessel Disease White Matter Hyperintensities

Annals of Neurology, EarlyView.
Objective The objective of this study was to test if blood–brain barrier (BBB) disruption, detected using dynamic susceptibility contrast (DSC) imaging, would predict progression of white matter hyperintensities (WMHs) over the subsequent year in patients with chronic cerebrovascular disease. Methods The study included patients with a history of stroke
Richard Leigh, Kyle C. Kern, Nae‐Yuh Wang, Rebecca F. Gottesman, Clinton B. Wright   +4 more
wiley   +1 more source

Comparison of immediate and staged complete revascularization in patients with acute coronary syndrome and multivessel coronary disease: a systematic review and meta-analysis. [PDF]

BMC Cardiovasc Disord
Liu XY, Li YY, Wu XD, Lin Y, Lin X, Ye BH, Sun JC.   +6 more
europepmc   +1 more source

Anatomical Associations Between Focal Mitochondrial Metabolism and Patterns of Neurodegeneration in Amyotrophic Lateral Sclerosis

Annals of Neurology, EarlyView.
Objective Amyotrophic lateral sclerosis (ALS) has a very specific neuroimaging signature, but the molecular underpinnings of the strikingly selective anatomic involvement have not elucidated to date. Accordingly, a large neuroimaging study was conducted with 258 participants to evaluate associations between patterns of neurodegeneration and focal ...
Marlene Tahedl, We Fong Siah, Efstratios Karavasilis, Jennifer C. Hengeveld, Mark A. Doherty, Russell L. McLaughlin, Orla Hardiman, Ee Ling Tan, Foteini Christidi, Jana Kleinerova, Peter Bede   +10 more
wiley   +1 more source

Colchicine improves clinical outcomes in patients with coronary disease, will it result in similar benefits in peripheral artery disease? [PDF]

Eur Heart J Open
Tardif JC, Cuthill S.
europepmc   +1 more source

Multivessel coronary disease should be treated with coronary artery bypass grafting in all patients who are not (truly) high risk. [PDF]

JTCVS Open
Ghandakly EC, Bakaeen FG.
europepmc   +1 more source

Racial and Ethnic Disparities in the Management of Chronic Coronary Disease. [PDF]

Med Clin North Am
Tang WL, Rodriguez F.
europepmc   +1 more source