Results 71 to 80 of about 10,498,114 (427)

Computed tomography coronary angiogram images, annotations and associated data of normal and diseased arteries [PDF]

arXiv, 2022
Computed Tomography Coronary Angiography (CTCA) is a non-invasive method to evaluate coronary artery anatomy and disease. CTCA is ideal for geometry reconstruction to create virtual models of coronary arteries. To our knowledge there is no public dataset that includes centrelines and segmentation of the full coronary tree.
arxiv  

Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease.

New England Journal of Medicine, 2009
BACKGROUND Percutaneous coronary intervention (PCI) involving drug-eluting stents is increasingly used to treat complex coronary artery disease, although coronary-artery bypass grafting (CABG) has been the treatment of choice historically.
P. Serruys, M. Morice, A. Kappetein, A. Colombo, D. Holmes, M. Mack, E. Ståhle, T. Feldman, M. Brand, E. Bass, N. V. Dyck, Katrin Leadley, K. Dawkins, F. Mohr, Boston Scientif   +14 more
semanticscholar   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Super-ego in patients with coronary artery disease [Super-ego oboljelih od bolesti koronarnih arterija srca] [PDF]

, 2011
In this paper, we explored the super-ego of patients with coronary artery disease. Research results have confirmed the initial hypothesis that a significant number of patients with coronary artery disease has rigorous super-ego.
Bilić, Vedran, Marčinko, Darko, Miličić, Davor   +2 more
core  

A New Approach in Risk Stratification by Coronary CT Angiography. [PDF]

, 2014
For a decade, coronary computed tomographic angiography (CCTA) has been used as a promising noninvasive modality for the assessment of coronary artery disease (CAD) as well as cardiovascular risks.
Budoff, Matthew J, Nakanishi, Rine
core   +3 more sources

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.

New England Journal of Medicine, 2016
BACKGROUND The discovery of low-frequency coding variants affecting the risk of coronary artery disease has facilitated the identification of therapeutic targets. METHODS Through DNA genotyping, we tested 54,003 coding-sequence variants covering 13,715
N. Stitziel, K. Stirrups, Nicholas G. D. Masca, J. Erdmann, P. Ferrario, I. König, P. Weeke, T. Webb, P. Auer, U. Schick, Y. Lu, He Zhang, M. Dubé, A. Goel, M. Farrall, G. Peloso, H. Won, R. Do, E. van Iperen, S. Kanoni, Jochen Kruppa, A. Mahajan, R. Scott, C. Willenberg, P. Braund, J. V. van Capelleveen, A. Doney, L. Donnelly, R. Asselta, P. Merlini, S. Duga, N. Marziliano, J. Denny, C. Shaffer, N. El-Mokhtari, A. Franke, O. Gottesman, S. Heilmann, C. Hengstenberg, P. Hoffman, O. Holmen, K. Hveem, J. Jansson, K. Jöckel, T. Kessler, J. Kriebel, K. Laugwitz, E. Marouli, N. Martinelli, M. McCarthy, Natalie R. van Zuydam, C. Meisinger, T. Esko, E. Mihailov, S. A. Escher, Maris Alver, S. Moebus, A. Morris, M. Müller-Nurasyid, M. Nikpay, O. Olivieri, Louis-Philippe Lemieux Perreault, Alaa AlQarawi, N. Robertson, K. Akinsanya, Dermot F. Reilly, T. Vogt, Wu Yin, F. Asselbergs, C. Kooperberg, R. Jackson, E. Stahl, K. Strauch, T. Varga, M. Waldenberger, Lingyao Zeng, A. Kraja, Chunyu Liu, G. Ehret, C. Newton‐Cheh, D. Chasman, Rajiv Chowdhury, M. Ferrario, I. Ford, J. Jukema, F. Kee, K. Kuulasmaa, B. Nordestgaard, M. Perola, D. Saleheen, N. Sattar, P. Surendran, D. Tregouet, R. Young, J. Howson, A. Butterworth, J. Danesh, D. Ardissino, E. Bottinger, R. Erbel, P. Franks, D. Girelli, A. Hall, G. K. Hovingh, A. Kastrati, W. Lieb, T. Meitinger, W. Kraus, Svati H. Shah, R. McPherson, M. Orho-Melander, O. Melander, A. Metspalu, C. Palmer, A. Peters, D. Rader, M. Reilly, R. Loos, A. Reiner, D. Roden, J. Tardif, J. Thompson, N. Wareham, H. Watkins, C. Willer, S. Kathiresan, P. Deloukas, N. Samani, H. Schunkert   +128 more
semanticscholar   +1 more source

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

FEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang, Kaien Hu, Zhaohui Fang, Sihai Wang, Jie Chen, Dengke Yin, Caiyun Zhang, Gefei Ma   +7 more
wiley   +1 more source

Mean platelet volume and coronary plaque vulnerability: an optical coherence tomography study in patients with non-ST-elevation acute coronary syndrome

BMC Cardiovascular Disorders, 2019
Background The association between mean platelet volume (MPV) and coronary plaque vulnerability in patients with non-ST-elevation ACS (NSTE-ACS) has not been investigated.
Jun Wang, Xing Li, Jun Pu, Siyu Jin, Lu Jia, Xiaomei Li, Fen Liu, Yining Yang   +7 more
doaj   +1 more source

CT imaging of coronary artery disease [PDF]

, 2012
Cardiovascular disease is the most common cause of death in developed countries. Particularly with regard to coronary artery disease, approximately 19 million people yearly worldwide either have acute coronary syndrome or die of sudden cardiac ...
Vassallo, Pierre
core  

Anatomical variants and coronary anomalies detected by dual-source coronary computed tomography angiography in North-eastern Thailand [PDF]

, 2018
Purpose: Congenital coronary anomalies are uncommon, with an incidence ranging from 0.17% in autopsy cases to 1.2% in angiographically evaluated cases. The recent development of dual-source coronary computed tomography angiography (coronary CTA) allows ...
Chaosuwannakit, Narumol
core   +1 more source