Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis. [PDF]
Aims This meta-analysis aims to quantify the association of reduced coronary flow with all-cause mortality and major adverse cardiovascular events (MACE) across a broad range of patient groups and pathologies.
Kelshiker MA+12 more
europepmc +2 more sources
Coronary flow reserve in stress-echo lab. From pathophysiologic toy to diagnostic tool [PDF]
The assessment of coronary flow reserve by transthoracic echocardiography has recently been introduced into clinical practice with gratifying results for the diagnosis of left anterior descending artery disease simultaneously reported by several ...
Rigo Fausto
doaj +11 more sources
Reduced coronary flow reserve in Anderson-Fabry disease measured by transthoracic Doppler echocardiography [PDF]
Coronary flow reserve was assessed in a patient with Anderson-Fabry disease complicated by symmetric left ventricular hypertrophy. Coronary flow reserve was measurable in all three major coronary arteries providing an opportunity to compare regional ...
Undas Anetta+2 more
doaj +5 more sources
The non-invasive documentation of coronary microcirculation impairment: role of transthoracic echocardiography [PDF]
Transthoracic Doppler echocardiographic-derived coronary flow reserve is an useful hemodynamic index to assess dysfunction of coronary microcirculation.
Galderisi Maurizio+2 more
doaj +5 more sources
Autologous CD34+ Stem Cell Therapy Increases Coronary Flow Reserve and Reduces Angina in Patients With Coronary Microvascular Dysfunction. [PDF]
Background: Coronary microvascular dysfunction results in angina and adverse outcomes in patients with evidence of ischemia and nonobstructive coronary artery disease; however, no specific therapy exists.
Henry TD+16 more
europepmc +2 more sources
The Concept of Coronary Flow Reserve
Coronary reserve has been defined as the ratio of coronary resistance under control (rest) conditions and of coronary resistance after maximal coronary vasodilation. The latter can be achieved by various interventions, the most important and clinically relevant example being intravenous administration of dipyridamole at 0.5 mg/kg of body weight.
B. E. Strauer
openalex +4 more sources
Continuous Versus Bolus Thermodilution‐Derived Coronary Flow Reserve and Microvascular Resistance Reserve and Their Association With Angina and Quality of Life in Patients With Angina and Nonobstructive Coronaries: A Head‐to‐Head Comparison [PDF]
Background Coronary flow reserve (CFR) and microvascular resistance reserve (MRR) are physiological parameters to assess coronary microvascular dysfunction. CFR and MRR can be assessed using bolus or continuous thermodilution, and the correlation between
Tijn P. J. Jansen+11 more
doaj +2 more sources
AT1 receptors: coronary flow and flow reserve [PDF]
Angiotensin II, through its effects at the angiotensin-type 1 receptor, elevates arterial pressure and exacerbates hypertensive heart disease. Alterations in coronary hemodynamics, including reductions in coronary blood flow and flow reserve promotes coronary insufficiency and contributes to the increased cardiovascular risk associated with these ...
Edward D. Fröhlich
openalex +4 more sources
Endothelial and non-endothelial coronary blood flow reserve and left ventricular dysfunction in systemic hypertension [PDF]
OBJECTIVES: We evaluated the impairment of endothelium-dependent and endothelium-independent coronary blood flow reserve after administration of intracoronary acetylcholine and adenosine, and its association with hypertensive cardiac disease ...
Aloísio Marchi Rocha+7 more
doaj +6 more sources
Effects of Intracoronary Alteplase on Microvascular Function in Acute Myocardial Infarction [PDF]
Background Impaired microcirculatory reperfusion worsens prognosis following acute ST‐segment–elevation myocardial infarction. In the T‐TIME (A Trial of Low‐Dose Adjunctive Alteplase During Primary PCI) trial, microvascular obstruction on cardiovascular ...
Annette M. Maznyczka+23 more
doaj +4 more sources