The Concept of Coronary Flow Reserve
Coronary reserve has been defined as the ratio of coronary resistance under control (rest) conditions and of coronary resistance after maximal coronary vasodilation. The latter can be achieved by various interventions, the most important and clinically relevant example being intravenous administration of dipyridamole at 0.5 mg/kg of body weight.
B. E. Strauer
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AT1 receptors: coronary flow and flow reserve [PDF]
Angiotensin II, through its effects at the angiotensin-type 1 receptor, elevates arterial pressure and exacerbates hypertensive heart disease. Alterations in coronary hemodynamics, including reductions in coronary blood flow and flow reserve promotes coronary insufficiency and contributes to the increased cardiovascular risk associated with these ...
Edward D. Fröhlich
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Continuous Versus Bolus Thermodilution‐Derived Coronary Flow Reserve and Microvascular Resistance Reserve and Their Association With Angina and Quality of Life in Patients With Angina and Nonobstructive Coronaries: A Head‐to‐Head Comparison [PDF]
Background Coronary flow reserve (CFR) and microvascular resistance reserve (MRR) are physiological parameters to assess coronary microvascular dysfunction. CFR and MRR can be assessed using bolus or continuous thermodilution, and the correlation between
Tijn P. J. Jansen+11 more
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Three-Dimensional Angiographic Characteristics versus Functional Stenosis Severity in Fractional and Coronary Flow Reserve Discordance: A DEFINE FLOW Sub Study [PDF]
Background: Coronary angiography alone is insufficient to identify lesions associated with myocardial ischemia that may benefit from revascularization.
Valerie Stegehuis+13 more
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Prior SARS‐CoV‐2 Infection Is Associated With Coronary Vasomotor Dysfunction as Assessed by Coronary Flow Reserve From Cardiac Positron Emission Tomography [PDF]
Background Cardiovascular complications from COVID‐19 contribute to its high morbidity and mortality. The effect of COVID‐19 infection on the coronary vasculature is not known.
Brittany Weber+13 more
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Multiparametric analysis of coronary flow in psoriasis using a coronary flow reserve companion. [PDF]
AbstractBackgroundCoronary microvascular dysfunction (CMD) is usually evaluated measuring coronary flow velocity reserve (CFVR). A more comprehensive analysis of CFVR including additional consideration of the associated logical companion‐CFVR, where hyperemic diastolic coronary flow velocity may act as surrogate, was applied in this study to elucidate ...
Tona F+11 more
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Background: The objective of the study was to measure pericoronal adipose tissue parameters, fractional flow reserve with coronary artery computed tomographic angiography (CTA), and difference of fractional flow reserve with coronary artery CTA, by using
Shuming Liu, Huiyuan Guan, Sheng Li
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Background. The treatment of coronary stenosis is decided by performing high risk invasive surgery to generate the fractional flow reserve diagnostics index, a ratio of distal to proximal pressures in respect of coronary atherosclerotic plaques.
Jermiah J. Joseph+5 more
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Prognostic Implications of Resistive Reserve Ratio in Patients With Coronary Artery Disease
Background Resistive reserve ratio is a thermodilution‐based index which integrates both coronary flow and pressure. Resistive reserve ratio represents the vasodilatory capacity of interrogated vessels including both epicardial coronary artery and ...
Seung Hun Lee+13 more
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Today, coronary artery disease (CAD) continues to be a prominent cause of death worldwide. A reliable assessment of coronary stenosis represents a prerequisite for the appropriate management of CAD.
Miłosz Starczyński+11 more
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