Coronary flow reserve in patients with normal coronary angiograms
It has been estimated that 20% of patients who undergo coronary angiography for the evaluation of chest pain have angiographically normal coronary vessels with no other car• diac cause for their discomfort. Although the natural history of this patient group is favorable (1-3), the mechanisms responsible for the pain frequently remain mysterious. In the
Marcus, Melvin L., White, Carl W.
openaire +2 more sources
Does the β-Blocker Nebivolol Increase Coronary Flow Reserve? [PDF]
Introduction: Nebivolol, a highly selective β1-adrenergic receptor-blocker, increases basal and stimulated endothelial nitric oxide (NO)-release. It is unknown, whether coronary perfusion is improved by the increase in NO availability.
Abrecht, Linda +8 more
core
Computational fluid dynamics modeling of symptomatic intracranial atherosclerosis may predict risk of stroke recurrence. [PDF]
BackgroundPatients with symptomatic intracranial atherosclerosis (ICAS) of ≥ 70% luminal stenosis are at high risk of stroke recurrence. We aimed to evaluate the relationships between hemodynamics of ICAS revealed by computational fluid dynamics (CFD ...
Chen, Xiangyan +13 more
core +3 more sources
Microfluidic engineering enables the fabrication of chitosan‐coated, melatonin‐loaded nanoemulsions with controlled release and enhanced physicochemical stability for space pharmaceutics. Interfacial biopolymer coating modulates droplet behavior under accelerated thermal stress and simulated microgravity.
Modupe Adebowale +3 more
wiley +1 more source
Pressure-bounded coronary flow reserve (Pb-CFR) is a novel technique that estimates the bounds of CFR from routine pressure measurements, but has not been compared with flow-derived CFR (CFR) regarding clinical outcome. We compared the long-term prognostic value of Pb-CFR versus CFR.
Gilbert Wijntjens +12 more
openaire +1 more source
Evaluating the impact of fractional flow reserve-guided percutaneous coronary intervention in intermediate coronary artery lesions on the mode of treatment and their outcomes: An Iranian experience. [PDF]
BACKGROUND: Today, the fractional flow reserve (FFR) guides the physician to select suitable patients with intermediate severity coronary lesions in angiography that should be treated or not with stent.
Akhbari, Mohammad Reza +7 more
core +3 more sources
Flexible sweat sensor patch integrating graphene‑interfaced gold microelectrodes functionalized with bio‑receptors and ion‑selective membrane, coupled with a capillary‑driven microfluidic layer and portable potentiostat electronics for multiplexed monitoring of inflammatory, metabolic, and electrolyte biomarkers in microliter sweat volumes.
Roomia Memon +4 more
wiley +1 more source
The multi-modality cardiac imaging approach to the Athlete's heart: an expert consensus of the European Association of Cardiovascular Imaging [PDF]
The term 'athlete's heart' refers to a clinical picture characterized by a slow heart rate and enlargement of the heart. A multi-modality imaging approach to the athlete's heart aims to differentiate physiological changes due to intensive training in the
Abergel +91 more
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Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou +4 more
wiley +1 more source
Tetrahydrobiopterin restores impaired coronary microvascular dysfunction in hypercholesterolaemia [PDF]
Purpose: Tetrahydrobiopterin (BH4) is an essential co-factor for the synthesis of nitric oxide (NO), and BH4 deficiency may cause impaired NO synthase (NOS) activity.
Camici, Paolo +6 more
core +1 more source

