ABSTRACT Background Intravascular ultrasound (IVUS)‐guided optimization of suboptimal fractional flow reserve (FFR) following percutaneous coronary intervention (PCI) results in a significant increase in both post‐PCI FFR and minimal lumen and stent areas (MLA and MSA, respectively).
Frederik T. W. Groenland+9 more
wiley +1 more source
Prognostic Impact of Coronary Flow Reserve in Patients With Reduced Left Ventricular Ejection Fraction. [PDF]
Joh HS+37 more
europepmc +1 more source
Tetrahydrobiopterin restores impaired coronary microvascular dysfunction in hypercholesterolaemia [PDF]
Purpose: Tetrahydrobiopterin (BH4) is an essential co-factor for the synthesis of nitric oxide (NO), and BH4 deficiency may cause impaired NO synthase (NOS) activity.
Camici, Paolo+6 more
core +1 more source
Fluid-structure interaction simulations for the prediction of fractional flow reserve in pediatric patients with anomalous aortic origin of a coronary artery [PDF]
Computer simulations of blood flow in patients with anomalous aortic origin of a coronary artery (AAOCA) have the promise to provide insight into this complex disease. They provide an in-silico experimental platform to explore possible mechanisms of myocardial ischemia, a potentially deadly complication for patients with this defect. This paper focuses
arxiv
Steerable Delivery Sheath for Optimized LAA Closure: First Experience and Procedural Outcomes
ABSTRACT Background The new Amplatzer Steerable Delivery Sheath is a delivery system designed to improve ease‐of‐use and procedural results of left atrial appendage closure (LAAC). We aimed to compare procedural results after switching our LAAC program at a tertiary care center with the Amulet device to the Steerable Delivery Sheath, with a control ...
Matthias Mezger+4 more
wiley +1 more source
The importance of time-to-event analysis in measuring the prognostic impact of coronary flow reserve. [PDF]
Kelshiker MA+3 more
europepmc +1 more source
Does the β-Blocker Nebivolol Increase Coronary Flow Reserve? [PDF]
Introduction: Nebivolol, a highly selective β1-adrenergic receptor-blocker, increases basal and stimulated endothelial nitric oxide (NO)-release. It is unknown, whether coronary perfusion is improved by the increase in NO availability.
Abrecht, Linda+8 more
core
The Impact of Hydrostatic Pressure on Fractional Flow Reserve in Saphenous Vein Grafts
ABSTRACT Background The relationship between height differences related to graft anatomy and physiological pressure indices in coronary bypass grafts has not been studied. We sought to study the impact of hydrostatic pressure on fractional flow reserve (FFR) in saphenous vein grafts (SVGs).
Roel Hoek+13 more
wiley +1 more source
Estimation of FFR in coronary arteries with deep learning [PDF]
Coronary artery disease (CAD) is one of the most common causes of death in the European Union and the USA. The crucial biomarker in its diagnosis is called Fractional Flow Reserve (FFR) and its in-vivo measurement is obtained via an invasive diagnostic technique in the form of coronagraphy.
arxiv
Emergent Cardiac Surgery After Transcatheter Structural Heart Procedures: Narrative Review
ABSTRACT Transcatheter structural heart procedures have become standard therapy for elderly patients with high surgical risk. Over time, these procedures have significantly increased worldwide, accompanied by a concomitant reduction of major complications, including those requiring emergent cardiac surgery (ECS).
Miriam Compagnone+7 more
wiley +1 more source