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Coronary CT-Derived Fractional Flow Reserve
Current Radiology Reports, 2017Coronary artery disease (CAD) is the leading cause of mortality in the United States and is accountable for a significant portion of overall healthcare costs. Non-invasive imaging plays a major role in the modern workup of CAD. This article will educate the reader on the foundations of computed tomography-derived fractional flow reserve (CT-FFR) and ...
von Knebel Doeberitz P. +9 more
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Invasive assessment of coronary flow reserve
Journal of Nuclear Cardiology, 2008Coronary angiography is a well-established invasive method of defining coronary anatomy and forms the basis for most decisions between medical therapy, surgery, and percutaneous revascularization in patients with coronary artery disease. Angiography is limited, however, in that it solely provides anatomic information.
Fadi, El-Ahdab, Michael, Ragosta
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Coronary flow reserve measurements in hypertension
Medical Clinics of North America, 2004Taken together, the diagnostic algorithm is leaded by a simple ECG stress test. In case of ST-segment depression the preferred image test should be stress ECG to bring patients at high risk for significant epicardial coronary artery stenosis to coronary angiography (and revascularization). In case of the lack of wall motion abnormalities (during stress-
Malte, Kelm, Bodo E, Strauer
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2015
The seminal concept of coronary flow reserve (CFR) was proposed experimentally by Lance K. Gould in 1974 [1]. Under normal conditions, in the absence of stenosis, coronary blood flow can increase approximately four- to sixfold to meet increasing myocardial oxygen demands.
Fausto Rigo, Eugenio Picano
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The seminal concept of coronary flow reserve (CFR) was proposed experimentally by Lance K. Gould in 1974 [1]. Under normal conditions, in the absence of stenosis, coronary blood flow can increase approximately four- to sixfold to meet increasing myocardial oxygen demands.
Fausto Rigo, Eugenio Picano
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Problems of Coronary Flow Reserve
Annals of Biomedical Engineering, 2000Coronary flow reserve is used to aid understanding why myocardial oxygen consumption may fail to meet demand. Its general aspects are well known, but the problems of using it are not. This manuscript describes three important factors that need to be considered when assessing coronary flow reserve.
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Coronary flow and flow reserve in children
Acta Paediatrica, 2004Aortic blood pressure affects coronary blood flow, but within the normal physiological blood pressure range coronary blood flow is constant. The coronary flow is pulsatile, being maximal in the early diastole. There is a smaller systolic flow component. The low systolic pressure in the right ventricle favours systolic flow.
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Catheterization and Cardiovascular Diagnosis, 1996
Doppler guidewire enables us to measure phasic coronary velocity and has been used for the measurement of coronary flow reserve (CFR). Although CFR is usually calculated by the quotient of peak flow velocity during papaverine infusion and flow velocity at rest, this assumption is true only if conduit vessel size is constant.
M, Takeuchi, Y, Nohtomi, A, Kuroiwa
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Doppler guidewire enables us to measure phasic coronary velocity and has been used for the measurement of coronary flow reserve (CFR). Although CFR is usually calculated by the quotient of peak flow velocity during papaverine infusion and flow velocity at rest, this assumption is true only if conduit vessel size is constant.
M, Takeuchi, Y, Nohtomi, A, Kuroiwa
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Coronary flow reserve is impaired in patients with slow coronary flow
Atherosclerosis, 2007Slow coronary flow (SCF) in a normal coronary angiogram is a well-recognized clinical entity, but its etiopathogenesis remains unclear. However, previous studies have suggested that microvascular abnormalities and endothelial dysfunction responsible for SCF.
Dogan, Erdogan +5 more
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Coronary vasomotion and coronary flow reserve during exercise
1991Coronary vasomotion and coronary blood flow are important determinants of myocardial perfusion in patients with coronary artery disease. New digital angiographic techniques allow to study, not only the dimensions of a stenotic lesion (quantitative coronary arteriography), but also coronary flow reserve (parametric imaging).
Hess OM +7 more
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The Concept of Coronary Flow Reserve
Journal of Cardiovascular Pharmacology, 1992Coronary reserve has been defined as the ratio of coronary resistance under control (rest) conditions and of coronary resistance after maximal coronary vasodilation. The latter can be achieved by various interventions, the most important and clinically relevant example being intravenous administration of dipyridamole at 0.5 mg/kg of body weight.
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