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Invasive assessment of coronary flow reserve
Journal of Nuclear Cardiology, 2008Coronary angiography is a well-established invasive method of defining coronary anatomy and forms the basis for most decisions between medical therapy, surgery, and percutaneous revascularization in patients with coronary artery disease. Angiography is limited, however, in that it solely provides anatomic information.
Fadi El-Ahdab, Michael Ragosta
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Coronary flow reserve measurements in hypertension
Medical Clinics of North America, 2004Taken together, the diagnostic algorithm is leaded by a simple ECG stress test. In case of ST-segment depression the preferred image test should be stress ECG to bring patients at high risk for significant epicardial coronary artery stenosis to coronary angiography (and revascularization). In case of the lack of wall motion abnormalities (during stress-
Malte Kelm, Bodo E. Strauer
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Lesion Eccentricity and Fractional Flow Reserve and Coronary Flow Reserve in Coronary Arteries
2013Fractional flow reserve has shown to be a gold standard in assessment of functional significance of coronary artery stenosis. Lesion eccentricity is an important geometric parameter which may affect the translational hemodynamics. Three dimensional quantitative coronary angiography (3D-QCA) was used to reconstruct the proximal or mid left anterior ...
Ashkan Javadzadegan +3 more
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Coronary Flow Resistance and Reserve
2015The coronary arteries are the initial vessels off of the aorta and eventually end in a rich capillary bed that provides blood to the myocytes in a one to one fashion (one capillary for each myocyte.) The myocardial oxygen concentration is at maximum such that any increase in myocardial blood flow (MBF) can only be accomplished by increase in coronary ...
Amr E. Abbas +2 more
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Effects of coronary stenoses on coronary flow reserve and resistance
The American Journal of Cardiology, 1974Abstract Resting coronary flow and regional distribution are not affected by narrowing of up to 85 percent of arterial diameter and therefore provide little insight into the effects of stenoses on coronary hemodynamics. However, maximal coronary flow and coronary flow reserve are markedly reduced by constrictions that do not affect resting flow ...
Kirk Lipscomb, K L Gould
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Catheterization and Cardiovascular Diagnosis, 1996
Doppler guidewire enables us to measure phasic coronary velocity and has been used for the measurement of coronary flow reserve (CFR). Although CFR is usually calculated by the quotient of peak flow velocity during papaverine infusion and flow velocity at rest, this assumption is true only if conduit vessel size is constant.
Akio Kuroiwa +2 more
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Doppler guidewire enables us to measure phasic coronary velocity and has been used for the measurement of coronary flow reserve (CFR). Although CFR is usually calculated by the quotient of peak flow velocity during papaverine infusion and flow velocity at rest, this assumption is true only if conduit vessel size is constant.
Akio Kuroiwa +2 more
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Impairment of coronary flow reserve in aortic stenosis
Journal of Applied Physiology, 2009Coronary flow reserve (CFR) is markedly reduced in patients with severe aortic valve stenosis (AS), but the exact mechanisms underlying this impairment of CFR in AS remain unclear. Reduced CFR is the key mechanism leading to myocardial ischemia symptoms and adverse outcomes in AS patients.
Garcia D +6 more
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Coronary vasomotion and coronary flow reserve during exercise
1991Coronary vasomotion and coronary blood flow are important determinants of myocardial perfusion in patients with coronary artery disease. New digital angiographic techniques allow to study, not only the dimensions of a stenotic lesion (quantitative coronary arteriography), but also coronary flow reserve (parametric imaging).
Hess OM +7 more
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Coronary Blood Flow and Coronary Vascular Reserve
1989The severity of coronary artery disease (CAD) has traditionally been evaluated by assessing coronary artery anatomy and left ventricular function during cardiac catheterization. The reduction in coronary artery blood flow caused by a particular stenosis has been inferred from its appearance on coronary arteriography.1 It is now well known that the ...
Peter R. Mahrer +2 more
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