Results 101 to 110 of about 1,922,582 (395)

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Analisis Faktor Risiko Merokok, Stres Dan Riwayat Keluarga Yang Berhubungan Dengan Kejadian Penyakit Jantung Koroner [PDF]

, 2014
Heart disease is the number one cause of death in the world, including Indonesia. According to the World Health Organization (WHO), 60 % of all causes of death of heart disease are coronary heart disease (CHD).
Sahrul, W. O. (Wa), Subijakto, S. (Sjarif), Sudayasa, I. P. (I)   +2 more
core  

Smoking Raises the Risk of Total and Ischemic Strokes in Hypertensive Men [PDF]

, 2003
To examine the relation between cigarette smoking and risk of stroke and coronary heart disease among Japanese, we conducted a 14-year prospective study of 3, 626 men aged 40-69, initially free from history of stroke and coronary heart disease.
IMANO Hironori, ISO Hiroyasu, KITAMURA Akihiko, NAITO Yoshihiko, OHIRA Tetsuya, SANKAI Tomoko, SATO Shinichi, SHIMAMOTO Takashi, TANIGAWA Takeshi, YAMAGISHI Kazumasa, 山岸 良匡, 谷川 武   +11 more
core   +1 more source

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Prognostic significance of triglyceride-glucose index in acute coronary syndrome patients without standard modifiable cardiovascular risk factors

Cardiovascular Diabetology
Background A significant percentage of patients with acute coronary syndrome (ACS) without standard modifiable cardiovascular risk factors (SMuRFs) are being identified.
Xiaoming Zhang, Yu Du, Tianhao Zhang, Zehao Zhao, Qianyun Guo, Xiaoteng Ma, Dongmei Shi, Yujie Zhou   +7 more
doaj   +1 more source

Meta-analysis of death and myocardial infarction in the DEFINE-FLAIR and iFR-SWEDEHEART trials: a hypothesis generating note of caution [PDF]

, 2017
In patients with coronary heart disease, revascularization can improve symptoms and in certain high-risk subgroups may improve prognosis. Coronary angiography provides anatomical information and the physiological significance of a stenosis can be ...
Berry, Colin, McClure, John D., Oldroyd, Keith G.   +2 more
core   +1 more source

Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision

Advanced Healthcare Materials, EarlyView.
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja, Lubaba A. Zaman, Chen Zhang, Milankumar Patel, Santhi Gorantla, Prasanta K. Dash, Howard E. Gendelman   +6 more
wiley   +1 more source

A patient with acute myocardial infarction with electrocardiogram Aslanger’s pattern

BMC Cardiovascular Disorders
Background Aslanger’s pattern in electrocardiogram (ECG) indicates that patients may have acute inferior myocardial infarction(AMI) with concomitant critical stenoses on other coronary arteries, which needs to be evaluated the timing of revascularization
Ming-hao Liu, Hao Li, Ang Li, Ru Liu, Hai-bo Liu, Li-jian Gao, Qing Gu, Lei Song   +7 more
doaj   +1 more source

Coronary heart disease and risk for cognitive impairment or dementia: Systematic review and meta-analysis

Alzheimer's & Dementia, 2017
Aims/Hypothesis Accumulating evidence suggests an association between coronary heart disease and risk for cognitive impairment or dementia, but no study has systematically reviewed this association.
K. Deckers, S. H. J. Schievink, Maria Rodriquez, R. V. van Oostenbrugge, M. V. van Boxtel, F. Verhey, S. Köhler   +6 more
semanticscholar   +1 more source

Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior

Advanced Healthcare Materials, EarlyView.
Fibrous structures are key elements of the native extracellular matrix and crucial for directing cell behavior. This review discusses how fiber properties such as composition, diameter, and alignment affect cell responses in 2D and 3D systems. Strategies for integrating fibrous cues into engineered tissues are highlighted, and future directions for ...
Zan Lamberger, Gregor Lang
wiley   +1 more source