Results 131 to 140 of about 1,021,856 (349)

Alpinetin Nanoparticles Alleviate Optic Nerve Injury Induced by Acute Glaucoma via LRP1‐PPARγ Mediated Regulation of Microglial Lipid Metabolism

Advanced Science, EarlyView.
Microglial lipid metabolic dysfunction drives neurodegeneration in glaucoma. We found loss of LRP1 causes lipid accumulation and inflammation. We developed alpinetin‐loaded nanoparticles (AlpNPs) that bind LRP1, activate the PPARγ‐LXRα‐ABCA1 pathway to restore lipid homeostasis, promote an anti‐inflammatory phenotype, and protect retinal ganglion cells,
Miao Wei, Yujia Huo, Jingchang Yuan, Xiao Fan, Xiaochen Wang, Sisi Tan, Xi Gao, Ruotong Ouyang, Hong Li   +8 more
wiley   +1 more source

Self‐Trapped Excitons in Carbon Quantum Dots with Large NIR‐II Photo‐Thermoelectric Catalysis Induce Pyroptosis for Cancer Therapy

Advanced Science, EarlyView.
The self‐trapped excitons in carbon quantum dots can serve as NIR‐II absorbers, which efficiently induce pyroptosis by driving the generation of reactive oxygen species through mild NIR‐II photothermal effect. Combined with local photophysical therapy and the cascade reaction of pyroptosis, it can activate systemic immunity and prevent tumor recurrence.
Tesen Zhang, Qingcheng Wang, Quansheng Cheng, Han Wang, He Feng, Hui Zhang, Mengbo Lin, Feili Cai, Zheng Fang, Ruo Wang, Gang Chen   +10 more
wiley   +1 more source

Importance of Atrial Fibrillation in Heart Failure Patients With Preserved Ejection Fraction Without Coronary Artery Disease

, 2020
Hisanori Kanazawa, Kenichi Tsujita
openalex   +2 more sources

Bio‐Inspired Micro‐Fin‐Assisted Multi‐Modal Vascular Intervention

Advanced Science, EarlyView.
A magnetic guidewire with a micro‐fin–integrated tip is introduced for multimodal cardiovascular navigation. The micro‐fins exploit fluid drag to augment magnetic torque, enabling bifurcation traversal at 15 mT, tolerating 45° misalignment, bidirectional crawling, and buckle self‐correction.
Xu Liu, Qiang Luo, Zhuoqun Cao, Hongde Li, Xi Chen, Hong Wang, Mao Chen, Ziyu Ren, Wenqi Hu   +8 more
wiley   +1 more source

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

Advanced Science, EarlyView.
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan, Yuanxiu Wei, Yiting Wu, Xinyue Su, Gangling Wang, Sisi Yang, Ziliang Ye, Yanjun Zhang, Hao Xiang, Yu Huang, Yiwei Zhang, Yuanyuan Zhang, Xianhui Qin   +12 more
wiley   +1 more source

Overtime work and incident coronary heart disease: the Whitehall II prospective cohort study [PDF]

, 2010
Marianna Virtanen, J. E. Ferrie, Archana Singh‐Manoux, M Shipley, Jussi Vahtera, Michael Marmot, Mika Kivimäki   +6 more
openalex   +1 more source

Modulation of Vascular Smooth Muscle Cell Multiplication, Apoptosis, and Inflammatory Damage by miR-21 in Coronary Heart Disease [PDF]

, 2021
Wei Liu, Yilin Li, Dongming Zhao
openalex   +1 more source

Neuroprotective Nanoplatform Integrating Antioxidant MXene Nanozymes and Ferroptosis Inhibitors for Targeted Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Cerebral ischemia‐reperfusion injury (CIRI) is a key pathological process limiting the efficacy of stroke therapy. This study has developed an innovative, multifunctional, brain‐targeted nanoplatform (RFP) containing MXene nanoenzymes and ferroptosis inhibitors.
Lu Wang, Chao Hou, Shuo Li, Lizhi Yang, Yiqun Lin, Sen Wang, Xiaohua Jia, Hui Hui, Wen He, Wei Zhang   +9 more
wiley   +1 more source

Prognostic value of serum glycated albumin in acute coronary syndrome patients without standard modifiable cardiovascular risk factors

Diabetology & Metabolic Syndrome
Background Glycated albumin (GA) has been demonstrated to be associated with adverse outcomes in patients with acute coronary syndrome (ACS). However, as a specific subgroup of ACS, a significant proportion of patients with ACS without standard ...
Xiaoming Zhang, Yu Du, Qianyun Guo, Xiaoteng Ma, Dongmei Shi, Yujie Zhou   +5 more
doaj   +1 more source

Predicting coronary heart disease in renal transplant recipients: A prospective study [PDF]

, 2004
Ludivine Dal Zuffo, Amir Kazory, Jean‐Marc Chalopin   +2 more
openalex   +1 more source