Results 191 to 200 of about 1,479,889 (356)

Therapeutic targeting of myeloid cells in liver fibrosis: Mechanisms and clinical prospects

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This review systematically summarizes the origin, recruitment, and differentiation regulation mechanisms of myeloid cells in driving hepatic fibrosis progression. By targeting these three critical phases, potential therapeutic strategies for liver fibrosis can be explored.
Yue Wang   +5 more
wiley   +1 more source

A deep learning model could screen for coronary heart disease from a "pseudo-normal" electrocardiogram. [PDF]

open access: yesMedicine (Baltimore)
Zhang Y   +7 more
europepmc   +1 more source

Changes in hemodynamics of pulmonary artery using Flowire in a canine model of acute pulmonary thromboembolism

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study investigated changes in pulmonary artery hemodynamics using a Flowire catheter and evaluated the accuracy of Doppler echocardiography in dogs with acute pulmonary thromboembolism (PTE). Ten healthy beagles were anesthetized, and acute pulmonary hypertension (PH) was induced by injecting 300‐μm dextran microspheres.
Tomohiko Yoshida   +3 more
wiley   +1 more source

Sheep femoral artery occlusion is well tolerated and does not result in ischemia

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Left femoral artery occlusion (yellow arrows) can be seen shortly after the lateral femoral circumflex artery origin, with distal arterial reconstitution. Sheep with femoral artery occlusion showed no change in pain scores nor mobility, thus making them an appropriate model for novel small diameter femoral artery graft studies. Abstract Objective Sheep
Timothy Shiraev   +10 more
wiley   +1 more source

Disease Characteristics and Treatments Associated with Outcome in Primary Angiitis of the Central Nervous System—A Multicenter Cohort Study in 163 Patients

open access: yesAnnals of Neurology, EarlyView.
Objective The aim was to determine patient, disease, and treatment characteristics associated with outcome in patients with primary angiitis of the central nervous system (PACNS) in a large multicenter German cohort. Methods In a retrospective, observational cohort study, we analyzed 163 adult patients who met the diagnostic criteria for PACNS.
Anna Lena Fisse   +29 more
wiley   +1 more source

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

open access: yesScience, 2016
P. Zanoni   +48 more
semanticscholar   +1 more source

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