Results 241 to 250 of about 1,026,322 (349)

Table 1_Joint impact of serum urate, renal function, and genetic susceptibility on coronary heart disease and ischemic stroke risk: a population-based study.docx

Huangda Guo (22695947), Siyue Wang (14262683), Hexiang Peng (17393114), Tianjiao Hou (5928908), Yixin Li (1540552), Hanyu Zhang (1425250), Mengying Wang (4443901), Tao Wu (16763), Jie Huang (104235)   +8 more
openalex   +1 more source

Safety and pharmacokinetics of a novel potent GABA analogue crisugabalin in Chinese subjects with various degrees of renal impairment

British Journal of Clinical Pharmacology, EarlyView.
Aims Crisugabalin is a novel calcium channel α2δ subunit ligand and a highly selective oral gamma‐aminobutyric acid (GABA) analogue developed for the treatment of diabetic peripheral neuropathic pain (DPNP) and postherpetic neuralgia (PHN). This study investigated pharmacokinetic properties and safety of crisugabalin in subjects with renal impairment ...
Shibeilei Lin, Ye Wang, Chao Hu, Yanhuan Feng, Xi Tang, Ping Fu, Jia Miao   +6 more
wiley   +1 more source

Associations between multimorbidity and unintentional falls among older adults with coronary heart disease. [PDF]

Front Public Health
Qi X, Yao X, Liu S, Fan L, Wu X, Qi X, Shi F, Wang S, Xue F.   +8 more
europepmc   +1 more source

Human vs. artificial intelligence: Physicians outperform ChatGPT in real‐world pharmacotherapy counselling

British Journal of Clinical Pharmacology, EarlyView.
Aims To assess the utility of the artificial intelligence (AI) chatbot ChatGPT (openly available version 3.5) in responding to real‐world pharmacotherapeutic queries from healthcare professionals. Methods Three independent and blinded evaluators with different levels of medical expertise and professional experience (beginner, advanced, and expert ...
Benjamin Krichevsky, Stefan Engeli, Stefanie M. Bode‐Böger, Felix Koop, Martin Schulze Westhoff, Sebastian Schröder, Carsten Schumacher, Thorben Pape, Dirk O. Stichtenoth, Johannes Heck   +9 more
wiley   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Plasma Protein Profile Associated With a Family History of Early-Onset Coronary Heart Disease. [PDF]

Circ Genom Precis Med
Wahrenberg A, Lind L, Åberg N, Häbel H, Ström M, Mälarstig A, Magnusson PKE, Kuja-Halkola R, Bergström G, Engström G, Hagström E, Jernberg T, Söderberg S, Östgren CJ, Svensson P.   +14 more
europepmc   +1 more source

Comparative effectiveness and safety of oral anticoagulants in patients with atrial fibrillation using antiarrhythmic drugs: An international cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aim Our international cohort study assessed the comparative effectiveness and safety of direct oral anticoagulants (DOACs) and vitamin K antagonists (VKAs) among patients with non‐valvular atrial fibrillation (NVAF) using antiarrhythmic drugs. Methods Using the United Kingdom's (UK's) Clinical Practice Research Datalink Aurum and Québec claims data, we
Fabian Maximilian Meinert, Jenny Dimakos, Ying Cui, Kristian B. Filion, Christel Renoux, Antonios Douros   +5 more
wiley   +1 more source

Coronary heart disease and type 2 diabetes metabolomic signatures in the Middle East. [PDF]

Front Endocrinol (Lausanne)
Elshrif M, Isufaj K, El-Menyar A, Ullah E, Beotra A, Al-Maadheed M, Mohamed-Ali V, Saad M, Al Suwaidi J.   +8 more
europepmc   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

The U-shaped association between normal-range serum bile acid levels and prognosis of Coronary Heart Disease. [PDF]

Front Endocrinol (Lausanne)
Xu Y, Ding N, Hua R, Wu Y, Li T, Yuan Z.
europepmc   +1 more source