Results 111 to 120 of about 96,509 (260)

Correlating Pulmonary Hemodynamics With HP 129Xe Dissolved‐Phase MRSI in a Controlled Porcine Intervention Study

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Pulmonary hypertension is related to a 1‐year mortality ranging from < 5% to > 20% in low‐ and high‐risk groups. Right heart catheterization is the diagnostic gold standard, associated with a 1.1% rate of severe adverse events, posing the need for a non‐invasive diagnostic tool.
Markus Phillip Andersen   +7 more
wiley   +1 more source

Current status and future perspectives of platelet function‐guided precision antiplatelet therapy for patients with cerebral infarction

open access: yesNeuroprotection, EarlyView.
Antiplatelet agents target the cyclooxygenase‐1 (COX‐1)/thromboxane A2 (TXA2) and adenosine diphosphate (ADP)‐P2Y12 (cytochrome P450 2C19 [CYP2C19]‐metabolized) platelet activation pathways, resulting in either drug resistance or over‐inhibition. The individualized therapeutic window balances ischemic risk (triggered by high on‐treatment platelet ...
Guoliang Zhu   +7 more
wiley   +1 more source

Multivalent Bi‐Specific Nanoerythrosomes: A Two‐Birds‐One‐Stone Approach to Combine Homologous and Active Targeting for Effective Thrombolysis

open access: yesSmall, EarlyView.
A multivalent bi‐specific nanoerythrosome (mBiNE@tPA) is developed as a “two‐birds‐one‐stone” platform that simultaneously exploits two principal thrombus components. By integrating erythrocyte membrane‐mediated homologous targeting with cRGD‐based active targeting to activated platelets, mBiNE@tPA achieves enhanced thrombus accumulation, triggered ...
Yu Huang   +10 more
wiley   +1 more source

Acute Coronary Occlusion in NSTEMI Patients: Prevalence, Clinical Characteristics and the Potential Role of Artificial Intelligence. [PDF]

open access: yesMedicina (Kaunas)
Stathakopoulou C   +10 more
europepmc   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

open access: yesVIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin   +3 more
wiley   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

open access: yesVIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe   +8 more
wiley   +1 more source

Proteinuria in Preeclampsia and Long‐Term Risk of Maternal Kidney and Cardiovascular Disease: A Population‐Based Cohort Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To examine the association between urinary protein excretion (UPE) level in preeclampsia and long‐term risk of maternal hypertension, chronic kidney disease (CKD), and cardiovascular disease (CVD). Design Nationwide, population‐based cohort study utilising routinely collected individual‐level data from medical databases.
Anne Høy Seemann Vestergaard   +6 more
wiley   +1 more source

Predicting Coronary Occlusion Risk during Redo-TAVR at First TAVR: Asymmetric Calcification Causes Failure. [PDF]

open access: yesCatheter Cardiovasc Interv
Onishi K   +12 more
europepmc   +1 more source

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