Results 161 to 170 of about 102,163 (289)

Leveraging the ADAM10 prodomain for selective inhibition to enhance recovery after myocardial infarction

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Inflammation plays a crucial role in the development and progression of numerous acute and chronic diseases such as myocardial infarction (MI) and heart failure. Targeting ADAM proteases, particularly ADAM10, holds promise for fine‐tuning inflammatory responses.
Erik Klapproth   +16 more
wiley   +1 more source

On the detection of acute coronary occlusion with the miniECG. [PDF]

open access: yesEur Heart J Digit Health
Zepeda-Echavarria A   +2 more
europepmc   +1 more source

Intravascular Ultrasound Analysis of Intraplaque Versus Subintimal Tracking in Percutaneous Intervention for Coronary Chronic Total Occlusions and Association With Procedural Outcomes

open access: green, 2017
Lei Song   +18 more
openalex   +2 more sources

Chronic Coronary Occlusions: Age, Morphology and Chance of Reopening [PDF]

open access: bronze, 1997
C. Vallbracht   +6 more
openalex   +1 more source

The anti‐fibrotic effects of novel heart failure pharmacotherapies in advanced heart failure patients

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Novel heart failure (HF) pharmacotherapies, including angiotensin receptor‐neprilysin inhibitor (ARNI) and sodium‐glucose cotransporter 2 inhibitors (SGLT2is), may confer cardiovascular benefits by attenuating myocardial fibrosis. However, direct evidence from human failing myocardial samples is limited.
Dávid Nagy   +10 more
wiley   +1 more source

Pharmacological inhibition of hydroxysteroid 11‐beta dehydrogenase type 1 (11‐βHSD1) after myocardial infarction preserves cardiac function in a translational mini‐pig model

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi   +19 more
wiley   +1 more source

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