Results 51 to 60 of about 102,163 (289)

Acute Inferior Wall Myocardial Infarction due to Occlusion of the Wrapped Left Anterior Descending Coronary Artery

Case Reports in Cardiology, 2013
Acute occlusion of the left anterior descending coronary artery (LAD) generally results in ST segment elevations in precordial leads and reciprocal ST segment depression in inferior leads.
Thottuvelil Narayanan Sunil Roy, Jafar Saeed Nagham, Rajappan Anil Kumar   +2 more
doaj   +1 more source

Feasibility and performance of a device for automatic self-detection of symptomatic acute coronary artery occlusion in outpatients with coronary artery disease: a multicentre observational study

The Lancet: Digital Health, 2019
Summary: Background: Time delay between onset of symptoms and seeking medical attention is a major determinant of mortality and morbidity in patients with acute coronary artery occlusion. Response time might be reduced by reliable self-detection.
Frederic Van Heuverswyn, MD, Marc De Buyzere, MSc, Mathieu Coeman, MD, Jan De Pooter, PhD, Benny Drieghe, MD, Mattias Duytschaever, PhD, Sofie Gevaert, PhD, Peter Kayaert, MD, Yves Vandekerckhove, MD, Joeri Voet, MD, Milad El Haddad, PhD, Peter Gheeraert, PhD   +11 more
doaj   +1 more source

Tie2‐Dependent Mechanisms Influence Leptomeningeal Collateral Dynamics and Reperfusion Following Stroke

Advanced Science, EarlyView.
This work demonstrates that endothelial EphA4 limits Tie2 activation and curbs leptomeningeal collateral expansion after ischemic stroke. Pharmacological activation of Tie2 by an Ang‐1 mimetic or genetic loss of EphA4 stimulates collateral vessel growth, improves cerebral perfusion, and enhances neurological recovery.
Alexandra M. Kaloss, Caroline de Jager, Kennedie Lyles, Nathalie A. Groot, Jackie Zhu, Yu Lin, Michael Chen, Hehuang Xie, John B. Matson, Michelle H. Theus   +9 more
wiley   +1 more source

Acute heart failure due to coronary subclavian steal syndrome after coronary artery bypass grafting

Clinical Case Reports, 2023
Key clinical message An axillo‐axillary bypass grafting is useful for coronary subclavian steal syndrome when occlusion of the proximal left subclavian artery.
Kosuke Nakata, Kosaku Nishigawa, Takashi Yoshinaga, Toshihiro Fukui   +3 more
doaj   +1 more source

Seipin‐Mediated Lipid Droplet Formation in Cardiomyocytes Ameliorates Cardiac Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu, Junxia Zhang, Yusi Chen, Geng Shen, Yufei Han, Zihao Zhou, Jinxuan Chen, Xuya Kang, Huilin Qu, Jiaxin Duanmu, Haibao Shang, Yingjia Li, Wei Huang, Yan Zhang   +13 more
wiley   +1 more source

Piezo1 Upregulation in Monocyte‐Derived Macrophages Impairs Post‐Myocardial Infarction Cardiac Repair via Defective Efferocytosis and Enhanced Ferroptosis

Advanced Science, EarlyView.
This study reports early Piezo1 activation in bone marrow monocyte‐derived macrophages (MoMs) during myocardial infarction (MI), which governs the fate and function of recruited macrophages. The recruited MoMs with increased Piezo1 expression exhibit increased ferroptosis and defective efferocytosis, delayed clearance of dead cells and resolution of ...
Lu Peng, Yunlong Xia, Huishou Zhao, Yongzhen Guo, Xiaoming Xu, Xue Han, Shiyue Wang, Fengyue Ding, Quanchi Liu, Congye Li, Yuan He, Zhaoyi Luo, Qiaojuan Wang, Xing Zhang, Feng Gao, Yajing Wang, Yulin Li, Shengpeng Wang, Ling Tao, Wenjun Yan   +19 more
wiley   +1 more source

Electrocardiographic signs of the left main coronary artery disease in acute coronary syndrome

Российский кардиологический журнал, 2020
Myocardial infarction (MI) due to the left main coronary artery (LMCA) disease is a life-threatening condition. Evaluation of ECG signs of LMCA occlusion is important because of revascularization emergency.
E. S. Eniseeva, K. V. Protasov, G. P. Gurtovaya   +2 more
doaj   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

A device for performing automated balloon catheter inflation ischemia studies.

PLoS ONE, 2014
Coronary collateral growth (arteriogenesis) is a physiological adaptive response to transient and repetitive occlusion of major coronary arteries in which small arterioles (native collaterals) with minimal to no blood flow remodel into larger conduit ...
Silas J Leavesley, Whitley Ledkins, Petra Rocic   +2 more
doaj   +1 more source

Bio‐Inspired Micro‐Fin‐Assisted Multi‐Modal Vascular Intervention

Advanced Science, EarlyView.
A magnetic guidewire with a micro‐fin–integrated tip is introduced for multimodal cardiovascular navigation. The micro‐fins exploit fluid drag to augment magnetic torque, enabling bifurcation traversal at 15 mT, tolerating 45° misalignment, bidirectional crawling, and buckle self‐correction.
Xu Liu, Qiang Luo, Zhuoqun Cao, Hongde Li, Xi Chen, Hong Wang, Mao Chen, Ziyu Ren, Wenqi Hu   +8 more
wiley   +1 more source