Results 201 to 210 of about 97,579 (254)

Diagnostic Agreement and Threshold Correspondence Between Resting Full‐Cycle Ratio and Nicorandil‐Based Fractional Flow Reserve in Intermediate Coronary Stenosis: A Prospective Single‐Center Registry

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background RFR has shown good aggregate agreement with FFR, including in prior Asian cohorts using intracoronary nicorandil. Where RFR‐FFR disagreement is concentrated relative to the FFR 0.80 decision boundary, and how the two binary thresholds correspond, remain incompletely characterized. Methods In a prospective single‐center registry, 300
Yonghoon Shin, Onyou Kim, Gi Won Yu, Yun Won Lee, Jung‐Joon Cha, Hyung Joon Joo, Jae Hyoung Park, Soon Jun Hong, Cheol Woong Yu   +8 more
wiley   +1 more source

The Effect of the MTHFR C677T Genotype Polymorphism on the Efficacy of Folic Acid Treatment for Hyperhomocysteinemia and Cardiovascular Endothelial Function

Chronic Diseases and Translational Medicine, EarlyView.
Flowchart of patient enrollment. ABSTRACT Background Cardiovascular disease remains a major public health burden. This study aimed to investigate the effect of the methylenetetrahydrofolate reductase (MTHFR) C677T genotype on folic acid treatment response and cardiovascular endothelial function in patients with hyperhomocysteinemia (HHcy).
Xiaohui Dou, Xijuan Zhang, Liang Zeng, Liheng Zeng, Xiaoyan Hu, Xuhong Jiang, Yahui Wan, Mingxia Ge, Xiaoyan Huang   +8 more
wiley   +1 more source

Invasive Coronary Physiology Study in Multivessel Coronary Artery Disease. [PDF]

Int J Angiol
Zahidin AM, Alkatiri AA, Mangkuanom AS, Iryuza N, Firman D.   +4 more
europepmc   +1 more source

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Coronary Physiology: From Basic Concepts to FFR and iFR

2021
Coronary angiography (CAG) complemented with invasive fractional flow reserve (FFR) assessment in assessing stenosis severity improves clinical outcomes compared to CAG alone in intermediate stenoses in stable coronary artery disease (CAD) [Tonino et al. N Engl J Med. 360(3):213–24, 2009; van Nunen et al. Lancet (London, England).
Stegehuis, Valérie E., Hoef, Tim P., Piek, Jan J.   +2 more
openaire   +2 more sources

Coronary physiology

Physiological Reviews, 1983
The major areas of normal coronary physiological research since Berne's 1964 review have been the measurement of ventricular transmural blood flow distribution with microspheres, the adenosine hypothesis of local metabolic control of coronary blood flow, and the autonomic control of coronary blood flow.
openaire   +2 more sources

Coronary physiology as an important adjunct to coronary intervention

Drugs of Today, 2000
The direct physiologic influence of a coronary stenosis, prior to an intervention for either de novo or restenotic lesions, can be easily and safely determined with sensor-tipped angioplasty guidewires, employing poststenotic absolute coronary flow velocity reserve (CVR), the relative CVR and the pressure-derived fractional flow reserve.
openaire   +2 more sources

Physiology of Coronary Microcirculation

2013
In this first chapter of the book, we discuss the functional anatomy and provide an in-depth description of the physiology of coronary microcirculation. The various intrinsic (i.e., vascular) and extrinsic (extravascular) physiologic mechanisms involved in the fine regulation of myocardial blood flow (MBF) are described.
Filippo Crea, Gaetano A. Lanza, Paolo G. Camici   +2 more
openaire   +1 more source

Coronary physiology: The importance of invasive coronary physiology in the real-world setting and the interaction between invasive coronary physiological indices

2023
This thesis explores the practical implications and outcomes associated with the use of coronary physiology measurements, specifically focusing on the relationship between macrovascular and microvascular indices. Despite extensive data from randomised clinical trials supporting FFR, there is limited real-world evidence, particularly in the Australian ...
openaire   +1 more source

Coronary physiology and pathophysiology

1987
In order to function as a pump that never stops, the heart uses vast amounts of energy, which it gets by generating large quantities of adenosine triphosphate (ATP) by oxidative metabolism. Testimony to this is the fact that mitochondria, the site of oxidative metabolism, make up 25–40% of the volume of left ventricular myocardial cells — the ...
openaire   +1 more source

Coronary Physiology to Optimize Percutaneous Coronary Intervention

Interventional Cardiology Clinics, 2023
openaire   +3 more sources