Results 151 to 160 of about 24,159 (191)
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Restenosis in intervened coronaries with hyperhomocysteinemia (RICH)
American Heart Journal, 2003Controversy exists regarding the contribution made by elevated serum homocysteine evels in raising the risk of restenosis after percutaneous coronary interventions. The objective of this study was to determine whether elevated homocysteine evels increase the risk of restenosis.Two hundred and two consecutive patients undergoing percutaneous coronary ...
Samuel A, Kojoglanian +4 more
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Management of restenosis after coronary intervention
American Heart Journal, 1996Coronary restenosis has proven to be the "Achilles heel" of percutaneous coronary interventions, frequently leading to repeated procedures. The pathogenesis of restenosis can be divided into four phases: early elasic recoil (hours to days), mural thrombus formation (hours to days), neointimal proliferation and extracellular matrix formation (weeks ...
G, Dangas, V, Fuster
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Coronary restenosis: a review of mechanisms and management
The American Journal of Medicine, 2003Percutaneous coronary interventions represent an attractive alternative to surgical revascularization; nevertheless, these techniques continue to be characterized by their propensity to elicit restenosis. Despite an exhaustive search for an effective pharmacotherapy to treat or prevent restenosis, hundreds of clinical trials have failed to identify an ...
Vivek, Rajagopal, Stanley G, Rockson
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Pathophysiology of coronary artery in‐stent restenosis
Acute Cardiac Care, 2007In-stent restenosis reflects the interaction of a cascade of molecular and cellular events occurring within the vessel wall. Coronary stenting induces localized injury to the vessel wall, which leads to the release of thrombogenic, vasoactive, and lymphocytes mitogenic factors that result in processes causing re-narrowing at the injured site.
A, Kibos, A, Campeanu, I, Tintoiu
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Restenosis, the Achilles' Heel of Coronary Angioplasty
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1998Coronary angioplasty is widely performed for the management of symptomatic coronary artery disease. With improvements in technique, operator experience, and tools, more complex lesions are being treated. Unfortunately, luminal renarrowing continues to limit the long‐term success of the procedure, resulting in the need for repeat revascularization in ...
R L, Wurdeman, D E, Hilleman, A N, Mooss
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Precision management of coronary in-stent restenosis
Trends in Cardiovascular MedicineThe advent of percutaneous coronary intervention (PCI) and intracoronary stent development marked a pivotal milestone in the management of acute coronary syndromes, significantly reducing morbidity and mortality worldwide. However, despite ongoing advancements in stent technology, treatment modalities, and diagnostic tools, in-stent restenosis (ISR ...
Travis M. Wilson +11 more
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The role of proto-oncogenes in coronary restenosis
Progress in Cardiovascular Diseases, 1997Arterial injury results in exposure of medial smooth muscle cells and adventitial fibroblasts to multiple growth factors that bind to specific cell surface receptors. These in turn activate second messengers and induce expression of immediate-early genes within minutes to hours after ligand binding to the receptor.
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Restenosis after coronary angioplasty
Current Problems in Cardiology, 1997M K, Hong +3 more
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