Results 11 to 20 of about 45,992 (237)

Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching [PDF]

, 2012
Bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs) synthesis, reduces neointimal formation in animal models of vascular injury and recently has been shown to inhibit in-stent late loss in a placebo-controlled phase II clinical trial.
Angelo Guglielmotti, Antonio Parisi, Armando Ialenti, Carla Cicala, Daniele De Filippis, Francesco Maione, Gianluca Grassia, Marcella Maddaluno, Maria Vittoria Di Lauro, Nicola Mascolo, Olivier Kocher, Pasquale Maffia, Teresa Iuvone   +12 more
core   +7 more sources

Design and testing of hydrophobic core/hydrophilic shell nano/micro particles for drug-eluting stent coating [PDF]

, 2018
In this study, we designed a novel drug-eluting coating for vascular implants consisting of a core coating of the anti-proliferative drug docetaxel (DTX) and a shell coating of the platelet glycoprotein IIb/IIIa receptor monoclonal antibody SZ-21.
A Arsiwala, A Bierhalz, A Tan, AW Heldman, B Almería, B O’brien, B O’Brien, C Stettler, CJ Pan, CJ Sweeney, CL Song, D Sun, DM Saylor, E Boersma, E Camenzind, ES Park, ES Thian, F Danhier, GY An, H Zhang, HG Wang, J Kanzer, J Riegger, J Yang, J Zhang, JB Slee, JJ Wykrzykowska, JM Lee, JV Natarajan, K Kolandaivelu, KH Bønaa, KS Lim, M Gawaz, M Zamani, M Zamani, MK Dong, MP Skinner, MT Ali, PS Douglas, PW Erruys, RH Müller, RK Aggarwal, RL Wilensky, S Freiberg, S Garg, S Hossfeld, S Jang, S Lee, S Mcginty, S Meng, S Puricel, S Yasuda, SJ Liu, T Inoue, T Nakano, TM Ko, U Baber, X Ma, X Wu, X Xi, Y Cao, YH Lee, Z Yang   +62 more
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Pathogen burden, inflammation, proliferation and apoptosis in human in-stent restenosis - Tissue characteristics compared to primary atherosclerosis [PDF]

, 2004
Pathogenic events leading to in-stent restenosis (ISR) are still incompletely understood. Among others, inflammation, immune reactions, deregulated cell death and growth have been suggested. Therefore, atherectomy probes from 21 patients with symptomatic
Abdelmegui AE, Alexander Jabs, Bauriedel G, Bauriedel G, Berndt Lüderitz, Carter AJ, Chiu B, Dirk Skowasch, Epstein SE, Farb A, Gerhard Bauriedel, Kearney M, Kol A, Komatsu R, Mayr M, Moreno PR, Neumann FJ, Nicolas Wernert, O'Brien ER, Pickering JG, René Andrié, Sabine Dinkelbach, Simonton CA, Thomas M. Schiele, Zohlnhofer D   +24 more
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PROSPECTS FOR THE USE OF BIOMARKERS (ADIPONECTIN, P-SELECTIN, INTEGRIN Ββ3) AS BIOCHEMICAL PREDICTORS OF RESTENOSIS IN PATIENTS WITH ISCHEMIC HEART DISEASE AFTER CORONARY STENTING

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2018
Aim.To analyze the literature data about the role of adiponectin, P-selectin and integrin β3 in the pathogenesis of the development of in-stent restenosis in patients with coronary heart disease after coronary stenting, as well as the possibility of ...
Chernyak A. A., Snezhitskiy V. A.
doaj   +1 more source

Restenosis of Coronary Arteries in Patients with Coronavirus Infection: Case Series

Case Reports in Medicine, 2023
Introduction. Coronavirus infection is a risk factor for vascular thrombosis. This is of particular importance for patients undergoing myocardial revascularization since this infection can be a trigger for the formation of restenosis in the area of a ...
Gulnara Batenova, Lyudmila Pivina, Evgeny Dedov, Altay Dyussupov, Zhanar Zhumanbayeva, Yerbol Smail, Tatyana Belikhina, Laura Pak, Diana Ygiyeva   +8 more
doaj   +1 more source

Assessment of the role of IL6 and IL10 gene polymorphisms as a risk factor for the development of restenosis in patients after implantation of drug-eluting stents

RUDN Journal of Medicine, 2021
Relevance. Currently, the number of percutaneous coronary interventions continues to increase, which leads to an increase in the absolute number of restenosis cases, which is the main complication of the long-term postoperative period.
K. B. Timizheva, A. V. Aghajanyan, L. V. Tskhovrebova, Z. Kh. Shugushev, M. M. Azova   +4 more
doaj   +1 more source

Layer-by-layer biofabrication of coronary covered stents with clickable elastin-like recombinamers [PDF]

, 2019
Producción CientíficaCoronary artery disease is the leading cause of death around the world. Endovascular stenting is the preferred treatment option to restore blood flow in the coronary arteries due to the lower perioperative morbidity when compared ...
Fernández Colino, Alicia, Jockenhoevel, Stefan, Mela, Petra, Moreira, Ricardo, Rodríguez Cabello, José Carlos, Rütten, Stephan, Schmitz-Rode, Thomas, Wolf, Frederic   +7 more
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IN STENT RESTENOSIS (ISR) IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION (PCI) FOR CORONARY ARTERY DISEASE (CAD)

Pakistan Armed Forces Medical Journal, 2020
Objective: To study the frequency of In-Stent Restenosis and its treatment in patients undergoing Percutaneous Coronary Intervention for coronary artery disease. Study Design: Descriptive cross sectional study.
Waseem Raja, Naseer Ahmed Samore, Mohsin Saif, Javeria Kamran, Sidra Waheed, Naeem Tariq, Farhan Tuyyab, Abdul Hameed Siddiqui   +7 more
doaj   +1 more source

A predictive model involving serum uric acid, C-reactive protein, diabetes, hypercholesteremia, multiple lesions for restenosis risk in everolimus-eluting stent-treated coronary heart disease patients

Frontiers in Cardiovascular Medicine, 2022
PurposeAs a second-generation drug-eluting stent, the restenosis risk factors of the everolimus-eluting stent (EES) lack sufficient evidence. Therefore, the study investigated the in-stent restenosis occurrence and its predictive factors among patients ...
Qiang Feng, Ying Zhao, Haiyan Wang, Jiayu Zhao, Xun Wang, Jianping Shi   +5 more
doaj   +1 more source

Inhibition of in-stent stenosis by oral administration of bindarit in porcine coronary arteries [PDF]

, 2011
<p><b>Objective:</b> We have previously demonstrated that bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs), is effective in reducing neointimal formation in rodent models of vascular injury by reducing smooth ...
Baker, A.H., Biondi, G., Colombo, A., Di Lauro, M.V., Gordon, P., Grassia, G., Guglielmotti, A., Ialenti, A., Kennedy, S., Maddaluno, M., Maffia, P.   +10 more
core   +1 more source