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Preventing treatment failures in coronary artery disease: what can we learn from the biology of in-stent restenosis, vein graft failure and internal thoracic arteries?

Cardiovascular Research, 2020
Coronary artery disease (CAD) remains one of the most important causes of morbidity and mortality worldwide, and the availability of percutaneous or surgical revascularization procedures significantly improves survival.
C. Spadaccio   +6 more
semanticscholar   +1 more source

Coronary Restenosis

Journal of the American Academy of Nurse Practitioners, 1996
Return of angina within 6 months of a catheter-based treatment of coronary artery disease usually reflects restenosis due to an overly aggressive local healing response to the procedure-related arterial injury. The restenotic lesion should be treated aggressively.
C, Brown   +5 more
openaire   +2 more sources

Treatment of coronary in-stent restenosis: a systematic review

Journal of Geriatric Cardiology, 2018
Coronary stent implantation has significantly improved percutaneous coronary intervention and enabled the management of early complications of plain balloon angioplasty. However, a new complication has accompanied these improvements: in-stent restenosis (
L. Pleva, Pavel Kukla, O. Hlinomaz
semanticscholar   +1 more source

Prevention of Coronary Restenosis

Cardiology in Review, 1999
Percutaneous transluminal coronary angioplasty (PTCA) was introduced 22 years ago as a nonsurgical catheter-based treatment for obstructive coronary artery disease. Over the following 2 decades, major advances in equipment and techniques led to tremendous growth in the use of PTCA to treat coronary artery disease and angina.
P J, Casterella, P S, Teirstein
openaire   +2 more sources

Intravascular Brachytherapy for the Management of Repeated Multimetal-Layered Drug-Eluting Coronary Stent Restenosis

Circulation. Cardiovascular Interventions, 2018
Background: Because of the widespread acceptance of percutaneous coronary intervention with drug-eluting stents as an effective treatment strategy for in-stent restenosis, it is common to encounter multimetal layer stent restenosis in the recent years ...
M. Varghese   +9 more
semanticscholar   +1 more source

Costs of coronary restenosis (Lovastatin Restenosis Trial)

The American Journal of Cardiology, 1996
Within the Lovastatin Restenosis Trial, restenosis has been clearly shown to increase resource utilization and costs. While it is not possible to generalize these results to other patient populations, it is clear that successful efforts to decrease restenosis will certainly improve efficacy while decreasing follow-up costs and increasing the cost ...
S P, Gilbert   +3 more
openaire   +2 more sources

Paclitaxel-Coated Balloon vs Uncoated Balloon for Coronary In-Stent Restenosis: The AGENT IDE Randomized Clinical Trial.

Journal of the American Medical Association (JAMA)
Importance Drug-coated balloons offer a potentially beneficial treatment strategy for the management of coronary in-stent restenosis. However, none have been previously evaluated or approved for use in coronary circulation in the United States ...
Robert W. Yeh   +64 more
semanticscholar   +1 more source

Restenosis After Coronary Balloon Angioplasty

Annual Review of Medicine, 1991
A recurrence of stenosis (restenosis) following successful coronary angioplasty continues to be a frequent problem limiting the long-term efficacy of the procedure. An overexuberant reparative response to the arterial injury induced by balloon dilatation leads to intimal hyperplasia, the major mechanism responsible for restenosis. Although none has yet
R A, Lange, E D, Flores, L D, Hillis
openaire   +2 more sources

Coronary In-Stent Restenosis: Assessment with CT Coronary Angiography

Radiology, 2012
To compare accuracy and radiation exposure of a new computed tomographic (CT) scanner with improved spatial resolution (scanner A) with those of a CT scanner with standard spatial resolution (scanner B) for evaluation of coronary in-stent restenosis (ISR) by using invasive coronary angiography (ICA) and intravascular ultrasonography (US) as reference ...
D. Andreini   +14 more
openaire   +2 more sources

[Coronary restenosis].

Herz, 2019
Coronary restenosis is the answer of the arterial wall to a mechanical violation through balloon angioplasty, bare-metal (BM) stent implantation or rotational atherectomy through repeated narrowing. It has great clinical and prognostic relevance and occurs in approximately 30% of non-coated stents and in 10% of coated coronary stents. The wound healing
R J, Zotz   +3 more
openaire   +1 more source

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