Is there a role for oral triple therapy in patients with acute coronary syndromes without atrial fibrillation? [PDF]
© 2018 Bentham Science PublishersBACKGROUND: Acute coronary syndrome (ACS) patients, despite treatment with dual antiplatelet therapy (DAPT), have up to 10% risk of recurrent major adverse cardiac events (MACE) in the short term.
Akhtar, Zaki+3 more
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Automatic extraction of coronary arteries using deep learning in invasive coronary angiograms [PDF]
Accurate extraction of coronary arteries from invasive coronary angiography (ICA) is important in clinical decision-making for the diagnosis and risk stratification of coronary artery disease (CAD). In this study, we develop a method using deep learning to automatically extract the coronary artery lumen. Methods.
arxiv +1 more source
Safety of short-term dual antiplatelet therapy after drug-eluting stents:An updated meta-analysis with direct and adjusted indirect comparison of randomized control trials [PDF]
Background: Duration of dual antiplatelet therapy (DAPT) following drug-eluting stents (DES) remains controversial and is a topic of ongoing research.
Bulluck, Heerajnarain+3 more
core +1 more source
von Willebrand Factor unfolding mediates platelet deposition in a model of high-shear thrombosis [PDF]
Thrombosis under high-shear conditions is mediated by the mechanosensitive blood glycoprotein von Willebrand Factor (vWF). vWF unfolds in response to strong flow gradients and facilitates rapid recruitment of platelets in flowing blood. While the thrombogenic effect of vWF is well recognized, its conformational response in complex flows has largely ...
arxiv +1 more source
Design and testing of hydrophobic core/hydrophilic shell nano/micro particles for drug-eluting stent coating [PDF]
In this study, we designed a novel drug-eluting coating for vascular implants consisting of a core coating of the anti-proliferative drug docetaxel (DTX) and a shell coating of the platelet glycoprotein IIb/IIIa receptor monoclonal antibody SZ-21.
A Arsiwala+62 more
core +1 more source
Rationale and design of "Can Very Low Dose Rivaroxaban (VLDR) in addition to dual antiplatelet therapy improve thrombotic status in acute coronary syndrome (VaLiDate-R)" study : A randomised trial modulating endogenous fibrinolysis in patients with acute coronary syndrome [PDF]
© The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the ...
Gorog, Diana A+5 more
core +1 more source
Elevated Baseline Serum Fibrinogen: Effect on 2-Year Major Adverse Cardiovascular Events Following Percutaneous Coronary Intervention. [PDF]
BackgroundElevated fibrinogen is associated with short-term major adverse cardiovascular events (MACE) after percutaneous coronary intervention, but the relation with late MACE is unknown.Methods and resultsBaseline demographics and 2-year MACE were ...
Ang, Lawrence+7 more
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Circulating inflammatory and hemostatic biomarkers are associated with risk of myocardial infarction and coronary death, but not angina pectoris, in older men [PDF]
Aims: The extent to which hemostatic and inflammatory biomarkers are related to angina pectoris as compared with myocardial infarction (MI) remains uncertain.
Lennon, L+5 more
core +1 more source
Automated analysis of fibrous cap in intravascular optical coherence tomography images of coronary arteries [PDF]
Thin-cap fibroatheroma (TCFA) and plaque rupture have been recognized as the most frequent risk factor for thrombosis and acute coronary syndrome. Intravascular optical coherence tomography (IVOCT) can identify TCFA and assess cap thickness, which provides an opportunity to assess plaque vulnerability.
arxiv
AGMN: Association Graph-based Graph Matching Network for Coronary Artery Semantic Labeling on Invasive Coronary Angiograms [PDF]
Semantic labeling of coronary arterial segments in invasive coronary angiography (ICA) is important for automated assessment and report generation of coronary artery stenosis in the computer-aided diagnosis of coronary artery disease (CAD). Inspired by the training procedure of interventional cardiologists for interpreting the structure of coronary ...
arxiv +1 more source