Results 201 to 210 of about 131,755 (294)

Dapagliflozin does not impair microvascular hemorheology in type 2 diabetes mellitus: A multicenter randomized controlled trial (D‐PATH study)

Journal of Diabetes Investigation, EarlyView.
Graphical abstract illustrating the study design, physiological rationale, and key findings of the D‐PATH trial. Dapagliflozin, an SGLT2 inhibitor, lowers HbA1c and body weight while increasing hematocrit and erythropoietin levels. Although an elevated hematocrit could theoretically increase blood viscosity and impair microcirculatory flow, ex vivo ...
Yuki Nakatani, Nobuyuki Banba, Shoya Ono, Tomoki Turumi, Megumi Hoshiai, Takushi Sugiyama, Takashi Tomoe, Hajime Tamiya, Naoyuki Otani, Hiroyuki Sugimura, Hidekazu Ikemiyagi, Yusuke Ohya, Koji Yokokawa, Shinichiro Ueda, Yoshimasa Aso, Yasuhiro Maejima, Takanori Yasu   +16 more
wiley   +1 more source

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

Journal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer, Paulina Hoppa, Erzsébet Frank, Teadora Tyler, Istvan Adorjan   +4 more
wiley   +1 more source

Acute coronary thrombosis due to heparin-induced thrombocytopenia following improved COVID-19 pneumonia: A case report. [PDF]

J Cardiol Cases
Sakamoto Y, Sugimoto A, Iseki H.
europepmc   +1 more source

The changing epidemiology of human type 2 diabetes–associated atherosclerosis: Pathophysiological mechanisms and emerging treatment possibilities

Journal of Internal Medicine, EarlyView.
Abstract Type 2 diabetes (T2D) is a major global health concern strongly associated with atherosclerosis and subsequent macrovascular complications. These complications are the leading cause of death among T2D patients. Despite a decline in cardiovascular events over the last decade, individuals with T2D still have an approximately doubled risk ...
Dania Al‐Sharify, Jiangming Sun, Andreas Edsfeldt   +2 more
wiley   +1 more source

Cardiovascular Outcomes With SGLT‐2 Inhibitors in Patients With Type 2 Diabetes and Obstructive Sleep Apnoea: A Real‐World Analysis

Diabetes, Obesity and Metabolism, EarlyView.
Reuben L. Odai, Dennis Dela Tsagli, Anthony Alchaer, Laiba Sajjad, Kwame Adjei‐Sefah, Chukwuemeka Aghasili, Smith Frimpong, Hussam Farhoud   +7 more
wiley   +1 more source

Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases

Obesity Reviews, EarlyView.
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar, Joanna Razafiarison, Fawaz Alzaid, Fahd Al‐Mulla, Rasheed Ahmad   +4 more
wiley   +1 more source

Interplay of Probe Stability and Oscillation During Very‐High‐Power Short‐Duration Ablation in Pulmonary Vein Isolation for Atrial Fibrillation

Pacing and Clinical Electrophysiology, EarlyView.
This graphical abstract presents a comprehensive analysis of probe stability and oscillation during very high‐power short‐duration (vHPSD) pulmonary vein isolation (PVI) for atrial fibrillation. The findings indicate that oscillation velocity serves as a more reliable predictor of impedance drop and temperature changes than contact force alone ...
Ernesto Cristiano, Eduardo Celentano, Barbara Ignatiuk, Martina Renda, Elena Bia, Raffaele Rainone, Jacopo Viganò, Natasja M. S. De Groot   +7 more
wiley   +1 more source

Coronary Artery Aneurysm Thrombosis in a Patient With Marfan Syndrome

Coronary artery aneurysm in adults is associated with connective tissue disorders, including Marfan syndrome. Coronary artery aneurysms are at risk for thrombosis, which obstructs coronary flow and thus results in myocardial infarction. We present a case
Mohammed, Mustafa, Abdul-Nour, Khaled, Wexler, Benjamin, Keimig, Thomas, Lingam, Natesh, Hudson, Michael, Almajed, Abdulla, Almajed, M. Ramzi, Antishin, Shannon, Saleem, Abdulmalik   +9 more
core  

Electronic patient blood management monitoring using routine health record data: A proof‐of‐principle study monitoring perioperative tranexamic acid use

Transfusion, EarlyView.
Abstract Background Monitoring Patient Blood Management (PBM) practices against evidence‐based standards is essential for quality improvement; however, current approaches are limited. In the UK, perioperative tranexamic acid (TXA) use is a national quality standard, yet monitoring relies on manual audit cycles that are resource‐intensive and limited in
Muhammad Naim Che Rahimi, Paolo Polzella, Mehir Amin, Gardash Bakhishli, Simon Godley, Michael F. Murphy, Simon J. Stanworth, Hayley G. Evans   +7 more
wiley   +1 more source