Immunolocalization of KATP channel subunits in mouse and rat cardiac myocytes and the coronary vasculature. [PDF]
BACKGROUND: Electrophysiological data suggest that cardiac KATP channels consist of Kir6.2 and SUR2A subunits, but the distribution of these (and other KATP channel subunits) is poorly defined.
Artman, M+13 more
core +3 more sources
Use of the Instantaneous Wave-free Ratio or Fractional Flow Reserve in PCI [PDF]
BACKGROUND: Coronary revascularization guided by fractional flow reserve (FFR) is associated with better patient outcomes after the procedure than revascularization guided by angiography alone.
Al-Lamee, R+6 more
core +4 more sources
Anatomic and Hemodynamic Plaque Characteristics for Subsequent Coronary Events
ObjectivesWhile coronary computed tomography angiography (CCTA) enables the evaluation of anatomic and hemodynamic plaque characteristics of coronary artery disease (CAD), the clinical roles of these characteristics are not clear.
Seung Hun Lee+18 more
doaj +1 more source
Accelerated coronary vascular disease in the heart transplant patient: Coronary arteriographic findings [PDF]
Annual coronary arteriograms have been obtained from all heart transplant recipients at Stanford University Medical Center since 1969. Angiographic lesions in 81 transplant patients exhibiting coronary vascular disease were classified into three ...
Alderman, Edwin L.+4 more
core +1 more source
An Endothelial Contribution to Coronary Vessels [PDF]
Despite the profound impact of coronary artery disease on human health, the origins of the coronary blood vessels are poorly understood. Wu et al. use imaging and genetic techniques to show that the endocardium contributes to the coronary vessels and ...
del Monte, Gonzalo+1 more
core +1 more source
Diabetes mellitus and ischemic heart disease. the role of ion channels [PDF]
Diabetes mellitus is one the strongest risk factors for cardiovascular disease and, in particular, for ischemic heart disease (IHD). The pathophysiology of myocardial ischemia in diabetic patients is complex and not fully understood: some diabetic ...
De Marchis, Marialaura+8 more
core +2 more sources
Recombinant interleukin-1β dilates steelhead trout coronary microvessels : effect of temperature and role of the endothelium, nitric oxide and prostaglandins [PDF]
© 2015. Published by The Company of Biologists Ltd. Acknowledgements We thank Wenjuan Xu and Xin Xu (Hein Lab) for their excellent instruction in microvessel techniques, Dr David Heeley (Biochemistry Department, MUN) for assistance with selecting an ...
Amelio+81 more
core +3 more sources
Artificial Intelligence Models Reveal Sex-Specific Gene Expression in Aortic Valve Calcification
Summary: Male and female aortic stenosis patients have distinct valvular phenotypes, increasing the complexities in the evaluation of valvular pathophysiology.
Philip Sarajlic, MD+3 more
doaj
Microvascular dysfunction in the immediate aftermath of chronic total coronary occlusion recanalization [PDF]
Objectives The aim of this study was to compare microvascular resistance under both baseline and hyperemic conditions immediately after percutaneous coronary intervention (PCI) of a chronic total occlusion (CTO) with an unobstructed reference vessel in ...
Alamgir, Farquad+5 more
core +1 more source
Collateral donor artery physiology and the influence of a chronic total occlusion on fractional flow reserve [PDF]
Background— The presence of a concomitant chronic total coronary occlusion (CTO) and a large collateral contribution might alter the fractional flow reserve (FFR) of an interrogated vessel, rendering the FFR unreliable at predicting ischemia should the ...
Alahmar, A.+15 more
core +1 more source