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An Endothelial Contribution to Coronary Vessels [PDF]
Cell, 2012 Despite the profound impact of coronary artery disease on human health, the origins of the coronary blood vessels are poorly understood. Wu et al. use imaging and genetic techniques to show that the endocardium contributes to the coronary vessels and that the coronary arteries and veins have multilineage origins.
Gonzalo del Monte +2 more
openaire +2 more sources
Sox17 Controls Emergence and Remodeling of Nestin-Expressing Coronary Vessels
Circulation Research, 2020 Supplemental Digital Content is available in the text. Rationale: The molecular mechanisms underlying the formation of coronary arteries during development and during cardiac neovascularization after injury are poorly understood.
Sara González-Hernández +5 more
semanticscholar +1 more source
Theranostics, 2021 Endothelial cells (ECs) constitute the innermost layer in all blood vessels to maintain the structural integrity and microcirculation function for coronary microvasculature. Impaired endothelial function is demonstrated in various cardiovascular diseases
X. Chang +6 more
semanticscholar +1 more source
Frontiers in Cardiovascular Medicine, 2022 ObjectiveTwo-dimensional speckle tracking echocardiography (2D-STE) has been used as a diagnostic tool for coronary artery disease (CAD). However, whether vessel supplied myocardial strain and strain rate (SR) predict the severity of coronary artery ...
Srisakul Chaichuum +8 more
doaj +1 more source
Development of the Coronary Vessel System [PDF]
Circulation Research, 2002 Formation of the coronary vessels is a fundamental event in heart development. Congenital abnormalities in the coronary system can have major deleterious effects on heart function. It is also possible that subtle variation in the patterning of coronary vessels has significant but uncharacterized effects on myocardial structure and function. In addition,
David E. Reese +2 more
openaire +2 more sources
The mysterious origins of coronary vessels [PDF]
Cell Research, 2013 The origin of the coronary vessels remains a mystery. Here we discuss recent studies that address this puzzle, including new work by Tian et al. recently published in Cell Research.
Bing Zhang, William T. Pu, William T. Pu
openaire +3 more sources
Frontiers in Cardiovascular Medicine, 2023 BackgroundSymptoms suggestive of myocardial ischemia are frequently encountered in patients with atrial fibrillation (AF) even in the absence of obstructive coronary artery disease.
Georgiana Pintea Bentea +5 more
doaj +1 more source
Immunolocalization of KATP channel subunits in mouse and rat cardiac myocytes and the coronary vasculature. [PDF]
, 2005 BACKGROUND: Electrophysiological data suggest that cardiac KATP channels consist of Kir6.2 and SUR2A subunits, but the distribution of these (and other KATP channel subunits) is poorly defined.
Artman, M +13 more
core +3 more sources
Anatomic and Hemodynamic Plaque Characteristics for Subsequent Coronary Events
Frontiers in Cardiovascular Medicine, 2022 ObjectivesWhile coronary computed tomography angiography (CCTA) enables the evaluation of anatomic and hemodynamic plaque characteristics of coronary artery disease (CAD), the clinical roles of these characteristics are not clear.
Seung Hun Lee +18 more
doaj +1 more source
Diabetes mellitus and ischemic heart disease. the role of ion channels [PDF]
, 2018 Diabetes mellitus is one the strongest risk factors for cardiovascular disease and, in particular, for ischemic heart disease (IHD). The pathophysiology of myocardial ischemia in diabetic patients is complex and not fully understood: some diabetic ...
De Marchis, Marialaura +8 more
core +2 more sources