Results 301 to 310 of about 1,823,543 (375)

Effectiveness and Safety of Reduced‐Dose Prasugrel in an East Asian Population: PRASFIT‐ACS Emulation Using National Health Insurance Claims Data

Clinical Pharmacology &Therapeutics, EarlyView.
Prasugrel is recommended for acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI). However, East Asians exhibit a stronger antiplatelet response, raising concerns about bleeding risks with standard dosing. This retrospective cohort study evaluated the real‐world effectiveness and safety of reduced‐dose prasugrel in
Li‐Wen Huang, Yee‐Jen Wu, Fang‐Ju Lin, Chien‐Chih Wu, Hsin‐Yi Huang, Chi‐Chuan Wang, Xiaojuan Li   +6 more
wiley   +1 more source

Feasibility Study of Triple-low CCTA for Coronary Artery Disease Screening Combining Contrast Enhancement Boost and Deep Learning Reconstruction. [PDF]

Rev Cardiovasc Med
Wu Z, Chen M, Wei Y, Shen C, Han W, Xu R, Zhou Z, Xu J.   +7 more
europepmc   +1 more source

Clinical Trials With Pragmatic Elements: A Review of Use Cases and Real‐World Data Utilization

Clinical Pharmacology &Therapeutics, EarlyView.
Clinical trials with pragmatic elements can capture diverse patient populations, enable efficient follow‐up, and reflect routine clinical practices; yet there is limited understanding of their design features, characteristics, and use of real‐world data (RWD). Based on a targeted search of PubMed/EMBASE (Jan‐2016 to Jul‐2024), a review was conducted to
Le Su, Lei Chen, Seema Betigeri, Nancy Dreyer, Helga Gardarsdottir, Rachele Hendricks‐Sturrup, Mehmet Burcu   +6 more
wiley   +1 more source

Squamate ventricular cardiomyocytes: Ploidy, proliferation, and heart muscle cell size in the leopard gecko (Eublepharis macularius)

Developmental Dynamics, EarlyView.
Abstract Background While heart function is broadly conserved across vertebrates, the cellular phenotype of muscle cells (cardiomyocytes) varies across taxa and throughout ontogeny. Emerging evidence suggests that some attributes may correlate with the capacity for spontaneous cardiomyocyte replacement following injury.
Kathy Jacyniak, Karemna Barrera Jaimes, Minh Hanh Doan, Jordyn M. Chartrand, Matthew K. Vickaryous   +4 more
wiley   +1 more source

Spider-Like Coronary Anatomy; the True Spider!

Arquivos Brasileiros de Cardiologia
Levent Cerit, Hamza Duygu, Kamil Gülşen, Hatice Kemal, Barcin Ozcem   +4 more
doaj   +1 more source

Coronary embolism resulting in myocardial infarction: diagnosis and treatment. [PDF]

Eur J Med Res
Chang S, Xu R, Dai Y, Li C, Lu H, Qin Q, Ma J, Qian J, Ge J.   +8 more
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Prophylactic VA-ECMO During Complex High-Risk PCI: A Randomized Controlled Trial. [PDF]

JACC Adv
Pan C, Zhu Y, Zhao J, Zhang B, Hu S, Zhao C, Meng X, Zhou X, Su Y, Xing E, Lei P, Bai N, Ma J, Wang X, Lu A, Bai M.   +15 more
europepmc   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Lipoprotein(a) as an Independent Biomarker of Coronary Complexity: Prevalence, Clinical Correlates, and Diagnostic Utility in a North Indian Acute Coronary Syndrome Cohort. [PDF]

Cureus
Mahajan K, Himral S, Sharma JB, Sandal S, Bhatia T, Thakur R, Patel I, Mohite K, Chandel P, Bhutani J.   +9 more
europepmc   +1 more source