Results 51 to 60 of about 147,356 (246)

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

hapln1a + cells guide coronary growth during heart morphogenesis and regeneration

Nature Communications, 2023
Although several tissues and chemokines orchestrate coronary formation, the guidance cues for coronary growth remain unclear. Here, we profile the juvenile zebrafish epicardium during coronary vascularization and identify hapln1a + cells enriched with ...
Jisheng Sun, Elizabeth A. Peterson, Xin Chen, Jinhu Wang   +3 more
doaj   +1 more source

Ultrasound‐Triggered Nanobubbles for Endothelial‐Targeted Drug Delivery in the Detection and Treatment of Doxorubicin‐Induced Cardiotoxicity

Advanced Healthcare Materials, EarlyView.
The DA/VTP‐NBs selectively recognized cardiac ECs damaged by DIC and achieved cell‐level targeted imaging. Then US‐triggered controlled release successfully enabled the release of DAPA within the DA/VTP‐NBs at the site of injury. This precise on‐demand drug release approach amplifies a series of localized therapeutic effects through the mtDNA‐mediated ...
Jun Zhang, Yi Ling, Xin Li, Deng Liu, Li Dong, Xuemei Chen, Yingxin Sun, Yongning Shang, Yanli Guo   +8 more
wiley   +1 more source

Prevalence of overweight and obesity in 2-5 year olds and its relationship with parental obesity

مجله دانشگاه علوم پزشکی بیرجند, 2014
Background and Aim: The aim of the current study was to determine prevalence of obesity and overweight in 2-5 year olds and its association with parental obesity in Birjand.
Fatemeh Taheri, Toba Kazemi, Tahereh Ansarinezhad, Gholamreza Sharifzadeh   +3 more
doaj  

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Liquid Metal Microrobots for Magnetically Guided Transvascular Navigation

Advanced Materials, EarlyView.
Liquid metal‐based microrobots combine magnetic steering, intrinsic X‐ray visibility and softness, to navigate blood vessels even against flow. Under clinically relevant magnetic fields, liquid metal microrobots roll along vessel walls, cross endothelial barriers, and accumulate in target tissues.
Xiaohui Ju, Roshan Velluvakandy, Xianghua Wu, Miguel Angel Merlos Rodrigo, Zbyněk Heger, Kamila Bendíčková, Jan Frič, Martin Pumera   +7 more
wiley   +1 more source

Blood levels of nitric oxide and affection of coronary vessels in women under 55 years of age with ischemic heart disease

Терапевтический архив, 2004
Aim. To estimate content of nitric oxide (NO) metabolites in women under 55 years with reference to affection of coronary vessels as shown by coronaroangiography (CAG). Material and methods.
N G Vardugina, E G Volkova, N S Orlova
doaj  

Deployable 3D‐Printed Vascular Stent with Surface‐Catalysed Endogenous Nitric Oxide Generation

Advanced Materials, EarlyView.
A deployable 3D‐printed vascular stent was fabricated with surface‐catalyzed endogenous nitric oxide generation, representing a promising new direction for stent development. The stent can be remotely controlled by magnetic force in its compressed state and fully deployed at the target site using an untethered heat source, potentially eliminating the ...
Kun Zhou, Zifei Han, Kang Lin, Di Wu, Siti Nur Asyura Adzlan, Qingqing Fan, Christina Cortez‐Jugo, Rona Chandrawati, Cyrille Boyer   +8 more
wiley   +1 more source

Advancing the Landscape of RNAi Nanotherapeutics for Ischemic Heart Disease

Advanced Materials, EarlyView.
RNA interference (RNAi) nanomedicine revolutionizes treatment regimens for ischemic heart diseases by enabling tailored, sequence‐anchored gene regulation. This review highlights the recent advances in nanotechnology‐driven RNAi therapeutics for myocardial ischemia and discusses the key design principles that govern efficient delivery, providing ...
Han Gao, Da Pan, Hélder A. Santos
wiley   +1 more source

Complete revascularization based on angiography derived fractional flow reserve versus incomplete revascularization in patients with ST-segment elevation myocardial infarction

Cardiology Journal
BACKGROUND: Nearly half of ST-segment elevation myocardial infarction (STEMI) patients present with significant multivessel coronary artery disease, they are at high risk of subsequent adverse events. Whether complete revascularization guided by coronary
Jiahui Liu, Kaiping Zhang, Xingang Wang, Zhaoping Liu, Ming Chen, Fangfang Fan, Jia Jia, Tao Hong, Jianping Li, Yong Huo, Yanjun Gong, Bo Zheng   +11 more
doaj   +1 more source