Results 81 to 90 of about 147,356 (246)

Mechanical and hydrodynamic effects of stent expansion in tapered coronary vessels. [PDF]

Biomech Model Mechanobiol, 2022
Liu X, Zhang W, Ye P, Luo Q, Chang Z.
europepmc   +1 more source

TrxR2 Lactylation Facilitates Mitochondrial Protection and Endothelial Ferroptosis Resistance in Diabetic Cardiomyopathy

Advanced Science, EarlyView.
TrxR2 deletion in diabetic mice suppresses TUFM‐AMPK‐FUNDC1‐dependent mitophagy in endothelial cells, resulting in SCP2 upregulation and mitochondrial translocation of ACSL4. Mitochondrial ACSL4 promotes mitochondrial eicosanoid biosynthesis and ferroptosis, thereby aggravating cardiac microvascular injury and diabetic cardiomyopathy.
Su Li, Muyin Liu, Chao Chen, Xinyan Li, Xiaopei Yan, Wentao Zhu, Wenyan Qiu, Qiyu Li, Xiangyu Sun, Chao Huang, Ming Yin, Zhangwei Chen, Yao Lu, Junbo Ge, Xiangqing Kong, Juying Qian, Yuqiong Chen   +16 more
wiley   +1 more source

Aortic Stenosis and the Tyrosine Kinase Inhibitor Nilotinib in Chronic Myeloid Leukemia

JACC. CardioOncology, 2020
Miguel Carracedo, PhD, Leif Stenke, MD, PhD, Anders Franco-Cereceda, MD, PhD, Magnus Bäck, MD, PhD   +3 more
doaj   +1 more source

Author Correction: Coronary vessels contribute to de novo endocardial cells in the endocardium-depleted heart. [PDF]

Cell Discov, 2023
Zhang M, Pu W, Li J, Han M, Han X, Zhang Z, Lv Z, Smart N, Wang L, Zhou B.   +9 more
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Impact of coronary bifurcation angle on computed tomography derived fractional flow reserve in coronary vessels with no apparent coronary artery disease. [PDF]

Eur Radiol, 2023
Tsugu T, Tanaka K, Nagatomo Y, Belsack D, Devos H, Buls N, Cosyns B, Argacha JF, De Maeseneer M, De Mey J.   +9 more
europepmc   +1 more source

Semiconducting Polymer Nanoparticles Enable Light‐Controlled Bidirectional Modulation of Nitric Oxide in Endothelial Cells

Advanced Science, EarlyView.
Bimodal modulation of nitric oxide in endothelial cells is achieved by light‐sensitive polymer nanoparticles. In dark, P3HT/PEDOT:PSS NPs boost intracellular ·NO, upregulate both endothelial and induced nitric oxide synthase, and drive a metabolic shift toward glycolysis.
Camilla Marzuoli, Andrea Pianetti, Elena Mancinelli, Anthea Villano, Matteo Vailati, Paola Lagonegro, Miryam Criado‐Gonzalez, Montserrat Climent, Hansel Comas‐Rojas, Leonardo Elia, Francesco Moccia, Gabriele Tullii, Maria Rosa Antognazza   +12 more
wiley   +1 more source

Targeted Thrombolysis via CCR2‐Engineered Macrophage‐Mimicking Microbubbles Safely Ablates Venous, Arterial, and Microvascular Thrombosis

Advanced Science, EarlyView.
CCR2‐Enhanced Macrophage Membrane–Camouflaged Microbubbles for MCP‐1–Mediated Thrombus Targeting and Ultrasound‐Triggered Urokinase Release. ABSTRACT The clinical management of thrombosis, a primary cause of death worldwide, is hampered by the limitations of current thrombolytic agents, including short half‐life and high risk of off‐target bleeding ...
Buying Li, Changjin Lu, Shijie Gao, Dandan Chen, Xue Heng, Kibret Mequanint, Malcolm Xing, Gaoxing Luo, Haisheng Li   +8 more
wiley   +1 more source

Spontaneous Coronary Artery Dissection: Sex Differences in Clinical Presentation and Outcomes From the Australian New Zealand Registry

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Spontaneous coronary artery dissection (SCAD) predominantly affects women with limited data in men. We aimed to determine sex differences in SCAD presentation, associated conditions, and major adverse cardiovascular events (MACE).
Fergal T. Temple, Quan Dang, Sonya Burgess, Swati Mukherjee, Jaya Chandrasekhar, Peter J. Psaltis, Leonard Kritharides, Nigel Jepson, Mithila Zaheen, Patrick Pender, Sarah Fairley, Abdul Ihdayhid, Jamie Layland, Richard Szirt, Seif El‐Jack, Aniket Puri, Esther Davis, Imran Shiekh, Ruth Arnold, Monique Watts, Hui Zhen Lo, Jessica A. Marathe, Rohan Bhagwandeen, Edwina Wing‐Lun, Ravinay Bhindi, Thomas J. Ford, Sidney Lo, Simone Marschner, Sarah Zaman   +28 more
doaj   +1 more source

Drug-Coated Balloon-Only Angioplasty Outcomes in Diabetic and Nondiabetic Patients with De Novo Small Coronary Vessels Disease. [PDF]

J Interv Cardiol, 2021
Benjamin BK, Lu W, Han Z, Pan L, Wang X, Qin X, Sun G, Wang X, Shan Y, Li R, Zheng X, Zhang W, Shi Q, Zhou S, Guo S, Qin P, Singh CP, Dong J, Qiu C.   +18 more
europepmc   +1 more source