Results 121 to 130 of about 610,902 (200)

Mixed lineage kinase 3 mediates SARS‐CoV‐2‐induced kidney injury via the Hsp70‐IL‐17A axis

Interdisciplinary Medicine, EarlyView.
Kidney samples from patients infected with severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) showed upregulated expression and activity of Mixed Lineage Kinase (MLK3). Based on the mechanistic studies, we identified MLK3 as a critical player in promoting SARS‐CoV‐2‐induced kidney injury.
Sandeep Kumar, Sunil Kumar Singh, Piush Srivastava, Sowdhamini Mahendiran, Rakesh Sathish Nair, Harsh Vyas, Saket Jha, Niraj Nag, Navin Viswakarma, Hitesh Kapoor, Swathi Suresh, Periannan Sethupathi, Sang‐Ging Ong, Jerrold S. Levine, Suman Setty, Mathayan Manikannan, Bellur S. Prabhakar, Basabi Rana, Ajay Rana   +18 more
wiley   +1 more source

Health and economic burdens of emerging infectious diseases in the USA, US territories and globally. [PDF]

BMJ Glob Health
Sevilla JP, Burnes D, Birjandi M, Knee JS, Villanueva JM, Durham DP, Nystrom SV, Petro CD, Lumpkins J, Schneider D, Bloom DE, White RC, Johnson RA.   +12 more
europepmc   +1 more source

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

Neutrophil dysmorphisms and extracellular trap-like structures in a patient with severe coronavirus disease 2019. [PDF]

Rev Soc Bras Med Trop
Cucinelli ADES, Santos DRD, Kang HC, Pereira IR.   +3 more
europepmc   +1 more source

Labor Market Institutions, Fiscal Multipliers, and Macroeconomic Volatility

Journal of Applied Econometrics, EarlyView.
ABSTRACT How do labor market institutions shape the transmission of government spending shocks and macroeconomic volatility? We develop a theoretical model in which labor market institutions affect fiscal transmission through their effect on wage rigidity, job separation, and matching frictions.
Maximilian Boeck, Jesús Crespo Cuaresma, Christian Glocker   +2 more
wiley   +1 more source

Clinical outcomes and costs associated with viral lower respiratory tract disease hospitalisations. [PDF]

BMJ Open Respir Res
Maslova E, Fagerås M, Tran T, Emmanuel B, Khezrian M, Branscombe N, Johnson S, Dalal G, Syed HU, Yehya N.   +9 more
europepmc   +1 more source

Serum Apelin‐13 and Galectin‐3 in COVID‐19: Associations With Routine Biochemical Parameters and Diagnostic Performance in a Case–Control Study

Journal of Clinical Laboratory Analysis, EarlyView.
Serum Apelin‐13 and Galectin‐3 levels were measured by ELISA in COVID‐19–positive patients and controls and evaluated alongside routine biochemical parameters. COVID‐19 patients showed significant alterations in liver, renal, inflammatory, and metabolic markers.
İsmail Uğurlu
wiley   +1 more source

Molecular Detection of Alpha- and Betacoronaviruses in Bats from Afar Region, Ethiopia. [PDF]

Vet Med Sci
Mengesha B, Romha G, Gebrezgabiher G.
europepmc   +1 more source

Commentary: Making Patient Data Count—Opportunities and Challenges for Open Science in Clinical Psychology

Journal of Clinical Psychology, EarlyView.
ABSTRACT Open science practices—such as preregistration, data and material sharing, and open‐access dissemination—are increasingly promoted across psychology, yet their specific value for clinical psychology has often been overlooked. This commentary argues that open science is particularly crucial for clinical psychology, where studies rely on small ...
Jan C. Cwik, Barbara Cludius, Dorothée Bentz, Marcel Riehle, Johannes C. Ehrenthal, Anke Haberkamp, Annika Clamor, Simon E. Blackwell, Maike Salazar Kämpf, Edgar Nazarenus, Rima‐Maria Rahal, Anne Möllmann, Jakob Fink‐Lamotte, Juliane Burghardt, Jan R. Boehnke, Kevin Hilbert   +15 more
wiley   +1 more source

Variations in trajectories of emotional and behavioural symptoms in children and young people with pre‐existing mental health and neurodevelopmental conditions before and during the COVID‐19 pandemic: A nested data linkage clinical cohort study

JCPP Advances, EarlyView.
Abstract Background Children and young people with pre‐existing mental health and neurodevelopmental conditions may have experienced heterogeneous mental health impacts during the COVID‐19 pandemic, but what facts may explain these variations are still unclear. We aimed to examine variations in the longitudinal trajectories of emotional and behavioural
Brian C. F. Ching, Alice Wickersham, Dominic Stringer, Sarjhana Ragunathan Brindha, Craig Colling, Ruby Morton, Valeria Parlatini, Johnny Downs, Emily Simonoff   +8 more
wiley   +1 more source