Results 161 to 170 of about 747,814 (341)

Comparison of the pathogenicity of multiple SARS‐CoV‐2 variants in mouse models

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We assessed the pathogenicity of various SARS‐CoV‐2 variants using two distinct mouse models. Our findings indicated that earlier variants, including WH‐09, Beta, and Delta, exhibited greater pathogenicity than later variants. Specifically, the Omicron variant demonstrated reduced pathogenicity, characterized by a shorter disease course and diminished ...
Qi Lv   +12 more
wiley   +1 more source

Avaliação da presença do vírus influenza em suínos no sul do Brasil. [PDF]

open access: yes, 2015
bitstream/item/57440/1/CUsersPiazzonDocumentsColecao-DigitalBoletim-de-Pesquisa-10.pdfProjeto/Plano de Ação: 16.00.300.04 ...
PALUDO, E.   +2 more
core  

AI in Neurology: Everything, Everywhere, All at Once Part 3: Surveillance, Synthesis, Simulation, and Systems

open access: yesAnnals of Neurology, EarlyView.
This final part 3 review builds on the practical applications discussed in part 2 and explores how artificial intelligence (AI) is transforming data management, neurological education, and neurological care across large healthcare networks and datasets. The review also highlights AI's role in real‐world and synthetic data, digital twins, and innovative
Matthew Rizzo
wiley   +1 more source

Atividade Física e Redução do Comportamento Sedentário durante a Pandemia do Coronavírus [PDF]

open access: diamond, 2020
Francisco José Gondim Pitanga   +2 more
openalex   +1 more source

Neuroimaging Biomarkers for Friedreich Ataxia: A Cross‐Sectional Analysis of the TRACK‐FA Study

open access: yesAnnals of Neurology, EarlyView.
Objective We aimed to quantify differences in the brain and spinal cord between Friedreich ataxia and controls, stratified by age and disease stage, including for the first time in young children. Methods TRACK‐FA is the largest prospective, longitudinal, multi‐modal neuroimaging study in Friedreich ataxia to date.
Nellie Georgiou‐Karistianis   +33 more
wiley   +1 more source

Doença por Coronavírus 2019: desafios emergentes e o ensino odontológico brasileiro

open access: gold, 2020
Matheus dos Santos Fernandez   +3 more
openalex   +2 more sources

Long‐Circulating Nanobody Confers Durable Prophylaxis against Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Infection

open access: yesAdvanced NanoBiomed Research, EarlyView.
This study explores Fc engineering to extend nanobody half‐lives in vivo. Herein, it is demonstrated that the circulation half‐life of Nanosota‐3A‐Fc, a novel nanobody with potent neutralizing activity against SARS‐CoV‐2 Omicron BA.1 variant, can be greatly prolonged by introducing M252Y/S254T/T256E (YTE) substitutions in the IgG1 Fc domain, which ...
Geetha Jyothi Vaskuri   +9 more
wiley   +1 more source

Novo coronavírus (Sars-CoV-2): difusão espacial e outro patamar para a socialização dos investimentos no Brasil

open access: diamond, 2020
Márcio Rogério Silveira   +4 more
openalex   +2 more sources

Single‐Molecule Protein Profiling Using Nanopores and Dimeric Aptamer‐Modified DNA Carriers

open access: yesAngewandte Chemie International Edition, Accepted Article.
Single‐molecule protein profiling offers unparalleled sensitivity for detecting rare biomarkers, with significant potential for early disease diagnosis and monitoring. Nanopore sensors enable the detection of proteins in solution and are well‐suited for clinical applications due to their high sensitivity and throughput.
Aleksandar Ivanov   +4 more
wiley   +1 more source

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