Results 221 to 230 of about 857,361 (295)

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo, Woojin Jung, Tham Thi Bui, Hwi‐yeol Yun, Jung‐woo Chae, Jeremiah D. Momper   +5 more
wiley   +1 more source

Prognosis of patients with coronavirus disease with or without anosmia: A systematic review. [PDF]

Malays Fam Physician
Albazah NIJ, Tiong JS, Yoshana M, Aishath A, Yeo YT, Elhariri S.   +5 more
europepmc   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said, Job R. Schippers, Leila Atmowihardjo, Yingxue Li, Mick S. van der Plas, Harm J. Bogaard, Lieuwe D. J. Bos, Ron A. A. Mathôt, Jurjan Aman, Eleonora L. Swart, Imke H. Bartelink   +10 more
wiley   +1 more source

Reply to "Currently, no appropriately designed studies have demonstrated a link between vitamin D levels and coronavirus disease 2019 severity". [PDF]

J Chin Med Assoc
Sheng CC, Su SY, Liang Y, Cheng HC, Huang HY, Chiu HH.   +5 more
europepmc   +1 more source

I Better “Not to”: Voluntary Sustainability Constraints in Mindful Organic Food Consumption

Sustainable Development, EarlyView.
ABSTRACT The purpose of this study is to understand constraints from limitations and skepticism to a form of agency in consumer ethics. Framed in Granular Interaction Thinking theory, our study addresses the research question of how the voluntary sustainability constraints leverage mindful consumption.
Neha Sharma, Agnieszka Kabalska, Swati Singh, Ralf Wagner   +3 more
wiley   +1 more source

Impact of Coronavirus Disease 2019 on Sick Sinus Syndrome: Trends in Incidence and Pacemaker Implantation. [PDF]

J Innov Card Rhythm Manag
Dulal D, Maraey A, Grubb B.
europepmc   +1 more source

Exploring the impacts of instructional modality in introductory statistics

Teaching Statistics, EarlyView.
Abstract The academic experiences at colleges and universities were significantly disrupted by the coronavirus disease 2019 pandemic with notable impacts on student learning, engagement, and success. We explore its effect on academic performance and student interaction at a mid‐sized public institution in the southeastern United States.
Lindsey Bell, Paul Hill, Keshav Jagannathan, Nicholas Pritchard   +3 more
wiley   +1 more source

Systematic review of the effects of neuromuscular electrical stimulation in post-coronavirus disease. [PDF]

S Afr J Physiother
Carvajal-Tello N, Segura-Ordóñez A, García-Muñoz H, Sánchez-Montoya LJ, Cambindo-Larrahondo LM, Muñoz-Chaux V, Barahona-Guzmán JP, Caballero-Lozada AF.   +7 more
europepmc   +1 more source

Recent advances of non‐invasive sensors for smart wearable respiratory monitoring

VIEW, EarlyView.
Respiration contains rich physiological and pathological information, making it one of the most fundamental and continuous vital signs. Respiration monitoring is a non‐invasive and simple, but incredibly powerful, tool for assessing health, managing disease, and tracking fitness.
Jianhui Chen, Baoxiang Yang, Chang Peng, Bao Yang, Licheng Zhou, Zhenyu Jiang, Zejia Liu, Yiping Liu, Liqun Tang   +8 more
wiley   +1 more source

A Qualitative Study of Japanese Medical Students' Perspectives on Clinical Practicum during Coronavirus Disease 2019. [PDF]

JMA J
Miyoshi T.
europepmc   +1 more source