Results 71 to 80 of about 8,330,269 (304)

COVID-19 (Coronavirus Disease 2019): A New Coronavirus Disease

Infection and Drug Resistance, 2020
Amin Sadeghi Dousari,1 Majid Taati Moghadam,2,3 Naghmeh Satarzadeh4,5 1Department of Microbiology, School of Medicine, Jiroft University of Medical Sciences, Jiroft, Iran; 2Department of Microbiology, School of Medicine, Iran University of Medical ...
Sadeghi Dousari A, Taati Moghadam M, Satarzadeh N   +2 more
doaj  

Metabolomics Profiling of Critically Ill Coronavirus Disease 2019 Patients: Identification of Diagnostic and Prognostic Biomarkers

Critical Care Explorations, 2020
Objectives:. Coronavirus disease 2019 continues to spread rapidly with high mortality. We performed metabolomics profiling of critically ill coronavirus disease 2019 patients to understand better the underlying pathologic processes and pathways, and to ...
Douglas D. Fraser, MD, PhD, Marat Slessarev, MD, MSc, Claudio M. Martin, MD, MSc, Mark Daley, PhD, Maitray A. Patel, BSc, Michael R. Miller, PhD, Eric K. Patterson, PhD, David B. O’Gorman, PhD, Sean E. Gill, PhD, David S. Wishart, PhD, Rupasri Mandal, PhD, Gediminas Cepinskas, DVM, PhD, On behalf of the Lawson COVID19 Study Team, Robert Arntfield, Ian Ball, Gordon Barkwell, Tracey Bentall, Karen Bosma, Saoirse Cameron, Eileen Campbell, David Carter, Carolina Gillio-Meina, Robert Hegele, Natalya Odoardi, Ram Singh, Kelly Summers, Sue Tereschyn   +26 more
doaj   +1 more source

The Italian coronavirus disease 2019 outbreak: recommendations from clinical practice. [PDF]

, 2020
Novel coronavirus 2019 is a single-stranded, ribonucleic acid virus that has led to an international pandemic of coronavirus disease 2019. Clinical data from the Chinese outbreak have been reported, but experiences and recommendations from clinical ...
Merli, G, G. Merli, Donati, A, Cortese, G, K. El‐Boghdadly, S. Falcetta, Greif, R., F. Petrini, Esposito, C, Falcetta, S, Cataldo, R, El-Boghdadly, K, Pintaudi, S, Bressan, F, R. Greif, F. Bressan, S. Pintaudi, R. Cataldo, G. Cortese, M. Sorbello, Petrini, F, A. Donati, Di Giacinto, I, Sorbello, M, I. Di Giacinto, Corso, R M, C. Esposito, R. M. Corso   +27 more
core   +2 more sources

Coagulopathy of Coronavirus Disease 2019

Critical Care Medicine, 2020
Objectives: Recent studies have reported a high prevalence of thrombotic events in coronavirus disease 2019. However, the significance of thromboembolic complications has not been widely appreciated. The purpose of this review is to provide current knowledge of this serious problem. Design:
Iba, Toshiaki, Levy, Jerrold H., Levi, Marcel, Connors, Jean Marie, Thachil, Jecko   +4 more
openaire   +3 more sources

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

Long-term outcome of pulmonary involvement in patients with coronavirus disease 2019: The role of high-resolution computed tomography and functional status – A prospective single-center observational study

Annals of Thoracic Medicine
BACKGROUND: Since its first outbreak, coronavirus disease 2019 (COVID-19) has led to a great deal of published literature highlighting the short-term determinants of morbidity and mortality.
Sadia Imtiaz, Enas M Batubara, Mohammed H Abuelgasim, Mahdi M Alabad, Lujain Mahmoud Alyousef, Nayef H Alqahtani, Alaa Y Sabbagh, Fawaz A Alharbi, Ahmed S Ibrahim   +8 more
doaj   +1 more source

Coronavirus disease 2019 and pregnancy [PDF]

American Journal of Obstetrics and Gynecology, 2021
Rasmussen, Sonja A., Jamieson, Denise J.
openaire   +2 more sources

Sarbecoviruses Suppress Innate Immunity by Recruiting PPM1A to Modulate STAT2 and ORF9b Phosphorylation

Advanced Science, EarlyView.
Sarbecovirus ORF9b recruits host phosphatase PPM1A to suppress innate immunity through dual mechanisms. PPM1A directly dephosphorylates ORF9b to sustain its activity and indirectly downregulates STAT2 phosphorylation to impair interferon signaling. Pharmacological inhibition of PPM1A restores antiviral responses and limits sarbecovirus replication ...
Lixiang Xie, Ziye Huang, Zhiyuan Zhang, Yiqiang Zhu, Xiaoqing Liu, Lei Wang, Tongyu Bi, Taizhen Liang, Jintao Lai, Meilin Hu, Guochang Qiu, Shiqi Xiao, Sen Liu, Yaoming Liu, Haiyue Rao, Tao Chen, Haojie Peng, Bin Zhang, Jia Tang, Qianying Li, Yaxin Li, Yuxin Hou, Weibo Yang, Hewei Jiang, Xiancai Ma   +24 more
wiley   +1 more source

Plasma Soluble CD14 Subtype Levels Are Associated With Clinical Outcomes in Critically Ill Subjects With Coronavirus Disease 2019

Critical Care Explorations, 2021
IMPORTANCE:. In bacterial sepsis, CD14 and its N-terminal fragment (soluble CD14 subtype, “Presepsin”) have been characterized as markers of innate immune responses and emerging evidence has linked both to coronavirus disease 2019 pathophysiology ...
F. Linzee Mabrey, MD, Eric D. Morrell, MD, Pavan K. Bhatraju, MD, MSc, Neha A. Sathe, MD, Sana S. Sakr, PhD, Sharon K. Sahi, BS, T. Eoin West, MD, MPH, Carmen Mikacenic, MD, Mark M. Wurfel, MD, PhD   +8 more
doaj   +1 more source

Border harm and affective injustice: The politics of anger at the Melilla border, Spain

American Journal of Community Psychology, EarlyView.
Abstract This article examines protests in a detention center in Melilla, Spain—a site where structural violence intersects with the everyday harms of confinement. Adopting a justice and dignity‐centered perspective, we analyze grassroots forms of resistance emerging at the border. The study focuses on the protests of Tunisian migrants and explores the
Corina Tulbure
wiley   +1 more source