Results 231 to 240 of about 317,688 (249)

Impact of Prior Intravenous Immunoglobulin and Plasmapheresis on Eculizumab or Ravulizumab Treatment for Generalized Myasthenia Gravis: An Analysis of the MG SPOTLIGHT Registry

open access: yesClinical and Experimental Neuroimmunology, EarlyView.
ABSTRACT Objective The complement component 5 inhibitor therapies (C5ITs) eculizumab and ravulizumab are approved for the treatment of generalized myasthenia gravis (gMG). We evaluated the real‐world effectiveness and safety of eculizumab and ravulizumab in patients with gMG with or without prior intravenous immunoglobulin (IVIg) or plasma exchange ...
Akiyuki Uzawa   +2 more
wiley   +1 more source

The economic effect of discrimination: Evidence from the restaurant sector

open access: yesContemporary Economic Policy, Volume 43, Issue 2, Page 226-259, April 2025.
Abstract Discrimination often leads to economic consequences for affected groups. This study examines the economic impact of consumer discrimination on Chinese restaurants in the U.S. during the COVID‐19 pandemic's onset. Using cell phone data and revenue records, it identifies a significant −10% relative decline in visits to Chinese restaurants by ...
Guanting Yi
wiley   +1 more source

LL‐37 Inhibits TMPRSS2‐Mediated S2' Site Cleavage and SARS‐CoV‐2 Infection but Not Omicron Variants

open access: yesCell Proliferation, EarlyView.
Cathelicidin LL‐37 inhibits SARS‐CoV‐2 by blocking the catalytic activity of TMPRSS2. The N764K mutation in the spike S2 subunit of Omicron variants confers resistance to LL‐37‐induced inhibition of TMPRSS2‐mediated S2' priming. ABSTRACT Continual evolution of SARS‐CoV‐2 spike drives the emergence of Omicron variants that show increased spreading and ...
Zhenfei Bi   +10 more
wiley   +1 more source

Ethical and Regulatory Considerations in the Clinical Translation of Pluripotent Stem Cell‐Derived NK Cell Therapies

open access: yesCell Proliferation, EarlyView.
Advancements in the generation of human pluripotent stem cell‐derived natural killer (PSC‐NK) cells have attracted considerable attention within the biomedical research community, offering a promising off‐the‐shelf technique for universal immune therapy.
Qianwen Chen   +5 more
wiley   +1 more source

Role of remdesivir for the treatment of COVID‐19 in patients with hematologic malignancy—A narrative review and expert opinion

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Created in BioRender. Ghezzi, S. (2025) https://BioRender.com/q1lticg. Abstract Background COVID‐19 remains a potentially severe condition for immunocompromised individuals, such as patients with hematologic malignancy. These patients are at increased risk of progressing to severe–critical or prolonged COVID‐19.
Malgorzata Mikulska   +5 more
wiley   +1 more source

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