Results 51 to 60 of about 422 (162)

A DATA DRIVEN MODEL TO PROMOTE PREPAREDNESS AND RESPOND INTELLIGENTLY TO PANDEMIC OUTBREAKS [PDF]

, 2022
The COVID-19 pandemic has had a major effect on various vital sectors of the economy, including education healthcare, and the industry. Governments have imposed strict regulations to reduce the spread of this global disease outbreak.
Al Senani, Safea Mohammed
core   +1 more source

Evolution of Point‐of‐Care Nucleic Acid Testing: From Amplification Chemistry to Intelligent and Data‐Driven Systems for Public Health

Aggregate, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in integrated point‐of‐care testing (POCT) systems for public health, encompassing isothermal nucleic acid amplification, CRISPR‐based signal amplification, device integration, and chemometric/artificial intelligence‐assisted data interpretation, with applications in infectious disease surveillance, food and ...
Yan Du, Jiaqi Li, Jinghong Li
wiley   +1 more source

Optimized Machine Learning Approach for Predicting Venous Clinical Severity Scale Outcomes in Yoga Practitioners [PDF]

Journal of Artificial Intelligence and System Modelling
Yoga is recognized as one of the oldest holistic health systems originating in India and has gained increasing scientific attention for its therapeutic potential in managing chronic vascular and circulatory disorders.
Behrouz Alefy, Faranak Kazemi
doaj   +1 more source

Hybrid Acquisition Processes in Surrogate-based Optimization. Application to Covid-19 Contact Reduction [PDF]

, 2022
International audienceParallel Surrogate-Assisted Evolutionary Algorithms (P-SAEAs) are based on surrogate-informed reproduction operators to propose new candidates to solve computationally expensive optimization problems. Differently, Parallel Surrogate-
Briffoteaux, Guillaume, Melab, Nouredine, Mezmaz, Mohand, Tuyttens, Daniel   +3 more
core  

Fully Synthetic Non‐Carbohydrate Heparin Mimetics—Perspectives for Therapeutic Anticoagulation and Beyond?

Archiv der Pharmazie, Volume 359, Issue 4, April 2026.
Fully synthetic sulfated non‐carbohydrate polymers for structurally mimicking the polysaccharide glycosaminoglycan heparin in its anticoagulant activities with further prospects to pleiotropic effects in oncology and in antiviral approaches. ABSTRACT Heparin is one of the oldest drugs on the market.
Katrin Nekipelov, Vito Ferro, Gerd Bendas   +2 more
wiley   +1 more source

Liquid–Liquid Phase Separation in Viral Infection and Immunology

MedComm, Volume 7, Issue 4, April 2026.
LLPS organizes viral replication and antiviral immunity. Viruses hijack LLPS to form replication factories and evade immune sensors, while hosts assemble LLPS‐driven signaling hubs (e.g., MAVS, RIG‐I, and SGs) to amplify interferon responses. Targeting these condensate interfaces offers novel therapeutic strategies against infectious diseases ...
Jiuzhi Xu, Lan Bai, Bin Wang, Hai Song, Long Zhang, Fangfang Zhou   +5 more
wiley   +1 more source

Innovative Optimization Algorithms for Large-Sized Industrial Scheduling Problems [PDF]

The problem of minimizing total quadratic completion time in flow shops presents a significant challenge in industries such as chemical, metallurgical, and ceramic manufacturing.
Alex Paranahyba Abreu, Helio Yochihiro Fuchigami   +1 more
core   +1 more source

High‐Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

Advanced Materials, Volume 38, Issue 13, 3 March 2026.
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton, Ajay S. Thatte, Junchao Xu, Zhangyi Luo, Hannah C. Safford, Kelsey L. Swingle, Jenna Muscat‐Rivera, Michael Kegel, Xuexiang Han, Ryann A. Joseph, Amanda M. Murray, Hannah C. Geisler, Ricardo C. Whitaker, Lulu Xue, Roman Spektor, Jilian R. Melamed, Drew Weissman, Michael J. Mitchell   +17 more
wiley   +1 more source

Optimizing Recurrent Neural Network-Based pH Prediction System of Halochromic Film for Chronic Wound Monitoring

IEEE Access
Chronic wounds, known for their prolonged healing and the associated financial strain on patients, highlight the growing need for effective monitoring methods.
Daeuk Kim, Ronnie S. Concepcion, Joseph Rey H. Sta. Agueda, John S. Martin Mondragon   +3 more
doaj   +1 more source

IgG‐Bridging–Seeded Synergistic Aggregation of SARS‐CoV‐2 Spikes Underlies Potent Neutralization by a Low‐Affinity Antibody

Advanced Science, Volume 13, Issue 11, 23 February 2026.
Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv, Peng Chen, Xiaobin Dai, Hu Xu, Ziheng Li, Zelin Shan, Jinqian Li, Fenglin Guo, Yuanfang Chen, Jiayi Li, Yiqian Huang, Guizhi Dong, Yifan Jiang, Liang Chen, Xuanyu Nan, Hanjun Zhao, Kang Zhang, Shilong Fan, Yuanchen Dong, Dongsheng Liu, Xinquan Wang, Deli Huang, Xiaojing Pan, Chunying Chen, Zhihua Liu, Li‐Tang Yan, Qi Zhang, Linqi Zhang, Yuliang Zhao, Yuhe Renee Yang   +29 more
wiley   +1 more source