Results 41 to 50 of about 333 (141)

Hybrid Acquisition Processes in Surrogate-based Optimization. Application to Covid-19 Contact Reduction [PDF]

, 2022
International audienceParallel Surrogate-Assisted Evolutionary Algorithms (P-SAEAs) are based on surrogate-informed reproduction operators to propose new candidates to solve computationally expensive optimization problems. Differently, Parallel Surrogate-
Briffoteaux, Guillaume, Melab, Nouredine, Mezmaz, Mohand, Tuyttens, Daniel   +3 more
core  

High‐Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

Advanced Materials, Volume 38, Issue 13, 3 March 2026.
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton, Ajay S. Thatte, Junchao Xu, Zhangyi Luo, Hannah C. Safford, Kelsey L. Swingle, Jenna Muscat‐Rivera, Michael Kegel, Xuexiang Han, Ryann A. Joseph, Amanda M. Murray, Hannah C. Geisler, Ricardo C. Whitaker, Lulu Xue, Roman Spektor, Jilian R. Melamed, Drew Weissman, Michael J. Mitchell   +17 more
wiley   +1 more source

A Reliable Kidney Stone Detection Method Using Inductive Transfer-Based Ensemble Deep Neural Networks [PDF]

Chronic kidney disease is a significant global health concern, with kidney stones being a major contributing factor to kidneydysfunction. Early and accurate detection is essential to prevent severe complications.
B.S.N. Murthy, Muthabathula Manoj Rajiv
core   +2 more sources

IgG‐Bridging–Seeded Synergistic Aggregation of SARS‐CoV‐2 Spikes Underlies Potent Neutralization by a Low‐Affinity Antibody

Advanced Science, Volume 13, Issue 11, 23 February 2026.
Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv, Peng Chen, Xiaobin Dai, Hu Xu, Ziheng Li, Zelin Shan, Jinqian Li, Fenglin Guo, Yuanfang Chen, Jiayi Li, Yiqian Huang, Guizhi Dong, Yifan Jiang, Liang Chen, Xuanyu Nan, Hanjun Zhao, Kang Zhang, Shilong Fan, Yuanchen Dong, Dongsheng Liu, Xinquan Wang, Deli Huang, Xiaojing Pan, Chunying Chen, Zhihua Liu, Li‐Tang Yan, Qi Zhang, Linqi Zhang, Yuliang Zhao, Yuhe Renee Yang   +29 more
wiley   +1 more source

A Coronavirus Herd Immunity Optimizer Based on Swarm Division

Shanghai Jiaotong Daxue xuebao
Aimed at the drawbacks of coronavirus herd immunity optimizer (CHIO), i.e., slow convergence speed and low optimization accuracy, a CHIO based on swarm division (SD-CHIO) is proposed.
LI Boqun, SUN Zhifeng
doaj   +1 more source

Mining Public Opinion on COVID-19 Vaccines using Unstructured Social Media Data [PDF]

, 2022
The emergence of the novel coronavirus (COVID-19), and the necessary separation of populations led to an unprecedented number of new social media users seeking information related to the pandemic.
Melton, Chad Aaron
core   +1 more source

Vaccine Incentives Harm Intrinsic Motivation: Evidence From a Priming Experiment

Health Economics, Volume 35, Issue 2, Page 312-331, February 2026.
ABSTRACT Monetary incentives for vaccination may undermine intrinsic motivation, but evidence on this effect remains scarce. We conducted an experiment among 513 vaccine‐hesitant adults to test whether priming individuals with a monetary incentive reduces their willingness to vaccinate against COVID‐19.
Johnny Huynh, Corey Jacinto, James Huynh
wiley   +1 more source

Advances and Applications of Spatial Proteomics: From Organellar Maps to Clinical Translation

ChemBioChem, Volume 27, Issue 1, January 2026.
Spatial proteomics provides high‐resolution maps of protein localization and trafficking by combining advanced mass spectrometry with complementary imaging and computational tools. Emerging low‐input and automated workflows are expanding its applicability to challenging clinical samples, supporting mechanistic disease research and biomarker discovery ...
Chiara Bernardini, Maike Däther, Franziska R. Traube   +2 more
wiley   +1 more source

Recent Advances in Strategies Against Measles Spread: Clinical and Epidemiological Aspects, Impact, Vaccine Innovations, and Sustainable Recommendations

The Scientific World Journal, Volume 2026, Issue 1, 2026.
Objectives Measles is a highly contagious disease, transmitted by respiratory droplets, whose spread is favored by disparities in vaccination coverage. This manuscript analyzes recent measles control strategies, analyzing their evolution, environmental repercussions, immune mechanisms, innovations in immunization, and sustainable solutions.
Abdelilah Merabti, Youssef Miyah, Mohammed Benjelloun, Chadia Zahouani, Wafaa Al Hassani, Rajae Lamsyah, Samia Essadki, Laila Ihrai, Saadia El Filali, Anis Sfendla, Mustapha Yaagoubi, Chakib Nejjari, Muhammad Altaf Khan   +12 more
wiley   +1 more source

Optimizing Recurrent Neural Network-Based pH Prediction System of Halochromic Film for Chronic Wound Monitoring

IEEE Access
Chronic wounds, known for their prolonged healing and the associated financial strain on patients, highlight the growing need for effective monitoring methods.
Daeuk Kim, Ronnie S. Concepcion, Joseph Rey H. Sta. Agueda, John S. Martin Mondragon   +3 more
doaj   +1 more source