Results 161 to 170 of about 3,864,754 (383)

Case Report: Unusual Neurological Features of Leigh Syndrome due to m.8993T>G Pathogenic Variant in the MT‐ATP6 Gene

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The MT‐ATP6 gene m.8993T>G pathogenic variant has been associated with Leigh syndrome, especially in patients exhibiting a high degree of heteroplasmy. Although patients may present with a wide phenotypic spectrum, characteristic findings include bilateral, symmetric hyperintensities in the basal ganglia and brainstem on brain MRI ...
Ramya Treitel, Julie McLaughlin, Marta Frigeni   +2 more
wiley   +1 more source

Promoting remyelination through cell transplantation therapies in a model of viral-induced neurodegenerative disease. [PDF]

, 2019
Multiple sclerosis (MS) is a central nervous system (CNS) disease characterized by chronic neuroinflammation, demyelination, and axonal damage. Infiltration of activated lymphocytes and myeloid cells are thought to be primarily responsible for white ...
Adami, Ager, Aharonowiz, Anghelina, Ben-Hur, Ben-Hur, Bergmann, Bergmann, Blanc, Blanc, Blurton-Jones, Brnic, Brustle, Cantuti-Castelvetri, Carbajal, Chang, Chen, Chen, Chucair-Elliott, Dandekar, Deshmukh, Dunnett, Fleming, Fleming, Frampton, Gage, Giovannoni, Glass, Gonzalez, Greenberg, Gupta, Halfpenny, Hardison, Hatch, Healy, Hosking, Huang, Ireland, Karamita, Keirstead, Kendall, Kerschensteiner, Kucharova, Lane, Lassmann, Lassmann, Lin, Lindborg, Lucchinetti, Mangale, Marie, Mei, Mei, Mei, Minagawa, Muller, Neumann, Oksenberg, Palfi, Parra, Pewe, Phares, Phillips, Picard-Riera, Plaisted, Plaisted, Pluchino, Pluchino, Poser, Prineas, Prineas, Ramakrishna, Redwine, Reidling, Rowe, Roy, Ruckh, Ruller, Salazar, Sarma, Schaumburg, Schlesinger, Smith, Steinman, Stohlman, Tabor-Godwin, Totoiu, Trandem, Traugott, Wang, Weinger, Weinger, Weinshenker, Wheeler, Whitman, Wu, Yagita, Zhang, Zhou, Zhu   +99 more
core   +1 more source

Household Financial Stress and Relationships During the COVID‐19 Pandemic: Findings From Australian Survey Data

Australian Journal of Social Issues, EarlyView.
ABSTRACT During the COVID‐19 pandemic, disruptions to finances and relationships were significant. Analysing Australian longitudinal survey data from May 2020 and August 2021, this study examines the Family Stress Model, which posits that financial stress influences relational dynamics within households.
Azadeh Abbasi Shavazi, Nicholas Biddle, Maria Jahromi   +2 more
wiley   +1 more source

N-glycoproteomic profiling revealing novel coronavirus therapeutic targets potentially involved in Cepharanthine's intervention

Medicine in Novel Technology and Devices, 2022
The Coronavirus disease 2019 (COVID-19) has posed a serious threat to global health and the world economy. Antiviral therapies targeting coronavirus are urgently required. The Cepharanthine (CEP) is a traditional Chinese herbal extract.
Wenlin An, Fengjuan Tian, Jing Li, Junge Chen, Yigang Tong   +4 more
doaj  

TMPRSS2 Contributes to Virus Spread and Immunopathology in the Airways of Murine Models after Coronavirus Infection

Journal of Virology, 2019
Broad-spectrum antiviral drugs against highly pathogenic coronaviruses and other emerging viruses are desirable to enable a rapid response to pandemic threats.
N. Iwata-Yoshikawa, T. Okamura, Yukiko Shimizu, H. Hasegawa, M. Takeda, N. Nagata   +5 more
semanticscholar   +1 more source

Coronavirus infections in veterinary medicine [PDF]

, 2005
The evidence that the “SARS-virus” could be an animal coronavirus and/or could originate from an animal coronavirus has increased the level of interest for coronavirus infections in animals. It was reported during the outbreak of SARS that researchers from HongKong University examined 25 animals representing eight species in a live animal market in ...
Olaf Weber, Axel Schmidt
openaire   +2 more sources

Antiviral effects and mechanism of Qi pi pill against influenza viruses

Animal Models and Experimental Medicine, EarlyView.
Qi pi pill presents anti‐influenza effect and inhibits viral replication in vitro by targeting both the viral RNA replication and the release of new viral particles. Furthermore, QPP modulates the production of proinflammatory cytokines induced by influenza infection in host cells.
Chengcheng Zhang, Jing Gao, Meiyue Dong, Carolina Q. Sacramento, Ping Li, Xiangyu Lian, Lingyuan Fan, Lijun Rong, Ruikun Du, Jingzhen Tian, Qinghua Cui   +10 more
wiley   +1 more source

Respiratory virus mRNA vaccines: mRNA Design, clinical studies, and future challenges

Animal Models and Experimental Medicine, EarlyView.
Abstract Respiratory infectious diseases frequently erupt on a global scale, with RNA viruses, such as SARS‐CoV‐2, RSV, and influenza viruses, posing challenges to vaccine development due to their high mutation rates. Traditional vaccine development cycles are lengthy and struggle to keep pace with rapidly evolving viruses, whereas messenger RNA (mRNA)
Linlin Zheng, Han Feng
wiley   +1 more source

Features of the clinical course of novel coronavirus infection COVID-19 in children

Лечащий Врач
Background. The problem of the clinical course and complications of a novel coronavirus infection (COVID-19) in children is given special attention in pediatrics.
T. B. Bikmetov, I. V. Zorin, R. S. Yakupova   +2 more
doaj   +1 more source

Novel coronavirus infection and pregnancy [PDF]

Ultrasound in Obstetrics & Gynecology, 2020
Yang, H., Wang, C., Poon, L. C.
openaire   +3 more sources