Results 171 to 180 of about 3,817,598 (310)

Protease inhibitors targeting coronavirus and filovirus entry. [PDF]

open access: yes, 2015
In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet   +10 more
core   +1 more source

The SARS-coronavirus-host interactome [PDF]

open access: yes, 2011
Coronaviruses (CoVs) are important human and animal pathogens that induce fatal respiratory, gastrointestinal and neurological disease. The outbreak of the severe acute respiratory syndrome (SARS) in 2002/2003 has demonstrated human vulnerability to ...
Brunn, Albrecht von   +27 more
core   +1 more source

Infection with Middle East respiratory syndrome coronavirus

open access: yesCanadian Journal of Respiratory Therapy, 2015
The Middle East respiratory syndrome coronavirus (MERS-CoV) was first recognized as a new febrile respiratory illness in Saudi Arabia in June 2012. As of September 21, 2015, the WHO reported 1569 laboratory-confirmed cases, including at least 554 related
Sami Alsolamy, Yaseen M Arabi
doaj  

Diverse effects of coronavirus-defective viral genomes on the synthesis of IFNβ and ISG15 mRNAs and coronavirus replication

open access: yesVirology Journal
Background The mechanism by which coronavirus-defective viral genomes (DVGs) affect coronavirus and host cells during infection remains unclear. A variety of DVGs with different RNA structures can be synthesized from coronavirus-infected cells, and these
Hsuan-Wei Hsu   +7 more
doaj   +1 more source

Coronavirus infection of polarized epithelial cells

open access: yesTrends in Microbiology, 1995
Epithelial cells are the first host cells to be infected by incoming c oronaviruses. Recent observations in vitro show that coronaviruses are released from a specific side of these polarized cells, and this polarized release might be important for the spread of the infection in vivo.
Horzinek, M.C.   +2 more
openaire   +5 more sources

Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong.

open access: yes, 2003
BACKGROUND: Health authorities worldwide, especially in the Asia Pacific region, are seeking effective public-health interventions in the continuing epidemic of severe acute respiratory syndrome (SARS).
Abu-Raddad, Laith J   +18 more
core   +1 more source

A review of coronavirus infection in the central nervous system of cats and mice. [PDF]

open access: yes, 2001
Feline infectious peritonitis (FIP) is a common cause of death in cats. Management of this disease has been hampered by difficulties identifying the infection and determining the immunological status of affected cats and by high variability in the ...
Foley, JE, Leutenegger, C
core  

Transmission dynamics of the etiological agent of SARS in Hong Kong: impact of public health interventions.

open access: yes, 2003
We present an analysis of the first 10 weeks of the severe acute respiratory syndrome (SARS) epidemic in Hong Kong. The epidemic to date has been characterized by two large clusters-initiated by two separate "super-spread" events (SSEs)-and by ongoing ...
Abu-Raddad, Laith J   +19 more
core   +1 more source

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