Results 251 to 260 of about 625,035 (300)

Signal Transducer and Activator of Transcription (STAT) Proteins Regulate Mucosal‐Associated Invariant T (MAIT) Cell Function

Immunology, EarlyView.
Integrated transcriptomic, proteomic and flow cytometry analyses reveal that STAT1 negatively regulates MAIT cell effector and glycolytic functions, while STAT3, STAT5 and HIF1α act as positive modulators. Targeting these pathways may offer new strategies to restore MAIT cell function in immune dysregulation and cancer.
Olivia J. Cheng, Eimear K. Ryan, Michael Bennett, Christy Clutter, Jackson G. Cacioppo, Jeffrey Aubé, Andy E. Hogan, Daniel T. Leung   +7 more
wiley   +1 more source

Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID

Immunology, EarlyView.
The complement cascade, a series of blood proteins that assists in the recognition and neutralisation of pathogens, either independently or in conjunction with antibodies, is persistently activated in patients with long COVID. We found that blood plasma samples from patients with long COVID contained elevated concentrations of the mannan‐binding lectin‐
Samuel B. K. Keat, Priyanka Khatri, Youssif M. Ali, Chanuka H. Arachchilage, Gregory Demopulos, Kirsten Baillie, Kelly L. Miners, Kristin Ladell, Samantha A. Jones, Helen E. Davies, David A. Price, Wioleta M. Zelek, B. Paul Morgan, Wilhelm J. Schwaeble, Nicholas J. Lynch   +14 more
wiley   +1 more source

Molecular Mechanisms and Potential Antiviral Strategies of Liquid-Liquid Phase Separation during Coronavirus Infection. [PDF]

Biomolecules
Wang Y, Zhou L, Wu X, Yang S, Wang X, Shen Q, Liu Y, Zhang W, Ji L.   +8 more
europepmc   +1 more source

A case of fulminant myocarditis associated with a novel coronavirus infection

, 2023
Yan B, Liu Z.
europepmc   +1 more source

Knowledge, Attitude, And Practices Regarding COVID-19 (Coronavirus) Infection Control and Prevention among Radiology Staff; a Perspective from Largest Private Tertiary Care Hospital in Pakistan. [PDF]

Arch Razi Inst
Shayan SMA, Noman K, Anwar A, Muhammad FHQ, Muzna S.   +4 more
europepmc   +1 more source

A Concept Analysis of Expertise Associated With Practicing Clinical Nurses in Hospital Settings

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim Analyse the concept of expertise among practicing clinical nurses in hospital settings. Background The generational loss of expert clinical nurses was exacerbated globally by the novel coronavirus. This ongoing loss combined with the increased complexity of hospitalised patients has prompted an urgent need to understand expertise among ...
Jonathan D. Hecht, Elizabeth M. Heitkemper, Valerie Danesh, Angela P. Clark, Linda H. Yoder   +4 more
wiley   +1 more source

The Interplay between Airway Cilia and Coronavirus Infection, Implications for Prevention and Control of Airway Viral Infections. [PDF]

Cells
Dai X, Xu R, Li N.
europepmc   +1 more source

Regional Community Building in Hard Times: Communal and Functional Filtering at EU Borders During the COVID‐19 Pandemic

JCMS: Journal of Common Market Studies, EarlyView.
Abstract Pandemics are times of closure. States typically restrict the entry of persons to protect their national communities from external health hazards. In this regard, the COVID‐19 pandemic presented the European Union (EU) with a severe challenge. We ask to what extent the border policies of EU member states during the pandemic supported regional ...
Christian Freudlsperger, Jana Lipps, Frank Schimmelfennig   +2 more
wiley   +1 more source

Compromised CD8+ T cell immunity in the aged brain increases severity of neurotropic coronavirus infection and postinfectious cognitive impairment. [PDF]

Aging Cell
Reagin KL, Lee RL, Williams LA, Cocciolone L, Funk KE.   +4 more
europepmc   +1 more source

A commentary on Zuniga‐Montanez and Davies et al.: how did COVID‐19 affect young children's language environment and language development? A scoping review

Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 602-605, April 2025.
It was early 2020, a week or two into Hilary Term, what everyone else calls Spring Term, but we at Oxford love our arcane traditions. I recall one of my graduate students, from China, coming to me ashen‐faced at the end one of my lectures on the effects of bilingualism on the linguistic and cognitive development of young learners.
Hamish Chalmers
wiley   +1 more source