Results 251 to 260 of about 468,607 (303)

The burden of COVID‐19 in hospitalized people with diabetes mellitus in Brazil: Insights from four years of the pandemic

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is more severe in people with diabetes mellitus due to immune dysfunction, exacerbated inflammation and increased risk of co‐morbidities and mortality.
Taís Mendes Camargo   +4 more
wiley   +1 more source

Association of Reduction in Continuity of Care During COVID‐19 Pandemic With Cardiovascular Diseases, Kidney Failure and All‐Cause Mortality for People With Diabetes: A Cohort Study in Hong Kong

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Continuity of care, a critical component of high‐quality primary care, was interrupted in people with diabetes mellitus during the COVID‐19 pandemic in Hong Kong. Research on whether reduced continuity of care was associated with higher complications and mortality risks is lacking.
Yuk Kam Yau   +11 more
wiley   +1 more source

Phase IIB, Randomized, Double‐Blind, Placebo‐Controlled Clinical Trial of Intravenous Defibrotide for the Prevention and Treatment of Respiratory Distress and Cytokine Release Syndrome in COVID‐19

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Introduction Endothelial dysfunction is key in COVID‐19 pathogenesis. This randomized, double‐blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS‐CoV‐2 infection and respiratory failure.
Ruben Jara Rubio   +38 more
wiley   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

open access: yesThe FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto   +9 more
wiley   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

open access: yesThe FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin   +2 more
wiley   +1 more source

Mortality trends for diabetes mellitus, hypertension and cardiovascular disease among people living with and without HIV in Brazil during the COVID‐19 pandemic, 2020–2022

open access: yesHIV Medicine, EarlyView.
Abstract Introduction People living with HIV (PLWH) face an increasing burden of non‐AIDS‐related chronic conditions. However, how the COVID‐19 pandemic affected chronic disease‐related mortality in this population remains unclear. We assessed changes in mortality among PLWH in Brazil during the COVID‐19 pandemic.
Tatyellen Natasha da Costa Oliveira   +7 more
wiley   +1 more source

The Perceived Impact of COVID‐19 Pandemic on Dental Therapy and Hygiene Students' Mental Wellbeing: A Qualitative Study

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Aim The aim of this research was to investigate any perceived impact from the COVID‐19 pandemic on the well‐being of dental therapy students. Methods Dental therapy students were invited to participate in focus groups to explore any impact of COVID‐19 on their wellbeing. One pilot and two online focus groups were conducted.
Morag Powell, James Donn, Vivian Binnie
wiley   +1 more source

Determinants of Dental Infection Control Costs: A Survey‐Based Multi‐Centre Analysis

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives This study investigated whether variations in costs related to dental infection control (DIC) practices exist depending on the characteristics of dental institutions. Methods Data were collected via surveys administered to 20 dental institutions (357 dental staff members) between April and May 2020.
Na‐Young Lee, Han‐Na Kim
wiley   +1 more source

When to consider an inborn error of immunity: clues for physicians

open access: yesInternal Medicine Journal, EarlyView.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

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