Feline infectious peritonitis: role of the feline coronavirus 3c gene in intestinal tropism and pathogenicity based upon isolates from resident and adopted shelter cats. [PDF]
Feline infectious peritonitis virus (FIPV) was presumed to arise from mutations in the 3c of a ubiquitous and largely nonpathogenic feline enteric coronavirus (FECV).
Golovko, Lyudmila +6 more
core +1 more source
Novel dangerous emergent coronavirus infection
The genetic diversity of coronaviruses and their variability are provided by high frequency of recombination of their genomic RNA that assists spontaneous emergence of viruses with new characteristics, which potentially may be agents of novel extremely ...
T. E. Sizikova +4 more
doaj +1 more source
The Role of Unfolded Protein Response in Coronavirus Infection and Its Implications for Drug Design
Coronavirus is an important pathogen with a wide spectrum of infection and potential threats to humans and animals. Its replication occurs in the cytoplasm and is closely related to the endoplasmic reticulum (ER).
Mei Xue, Li Feng
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Cross-protective immunity following coronavirus vaccination and coronavirus infection [PDF]
Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines have shown efficacy against SARS-CoV-2, it is unknown if coronavirus vaccines can also protect against other coronaviruses that may infect humans in the future. Here, we show that coronavirus vaccines elicited cross-protective immune responses against heterologous ...
Tanushree Dangi +9 more
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Cutaneous manifestations in children with the new coronavirus infection COVID-19
In late 2019, a new viral infection appeared in China, which spread around the world, causing a pandemic. The causative agent of the new coronavirus infection COVID-19 is the SARS-CoV-2 coronavirus.
O. B. Tamrazova +2 more
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Coronavirus infections and immune responses [PDF]
AbstractCoronaviruses (CoVs) are by far the largest group of known positive‐sense RNA viruses having an extensive range of natural hosts. In the past few decades, newly evolved Coronaviruses have posed a global threat to public health. The immune response is essential to control and eliminate CoV infections, however, maladjusted immune responses may ...
Li, Geng +11 more
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The V5A13.1 envelope glycoprotein deletion mutant of mouse hepatitis virus type-4 is neuroattenuated by its reduced rate of spread in the central nervous system. [PDF]
Following intracerebral inoculation of adult Balb/c Byj mice, the MHV-4 strain of mouse hepatitis virus (MHV) had an LD50 of less than 0.1 PFU, whereas its monoclonal antibody resistant variant V5A13.1 had an LD50 of 10(4.2) PFU.
Bloom, F +3 more
core +1 more source
Safety Recommendations for Evaluation and Surgery of the Head and Neck During the COVID-19 Pandemic [PDF]
Importance The rapidly expanding novel coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2, has challenged the medical community to an unprecedented degree.
Chinn, Steven B. +13 more
core +1 more source
Challenges for a Cancer Center in the Novel Coronavirus Pneumonia Epidemic
Introduction: The novel Coronavirus disease 2019 pandemic is sweeping through China, posing the greatest ever threat to its public health and economy.
Xiao Shan Wang MD, PhD +1 more
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Neurotropic Coronavirus Infections [PDF]
Neurotropic strains of the mouse hepatitis virus (MHV) cause a range of diseases in infected mice ranging from mild encephalitis with clearance of the virus followed by demyelination to rapidly fatal encephalitis. This chapter discusses the structure, life cycle, transmission, and pathology of neurotropic coronaviruses, as well as the immune response ...
Perlman, Stanley, Wheeler, D. Lori
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