Results 231 to 240 of about 492,232 (295)

From Survival to Recovery: 25 Years of Paediatric Critical Care Transformation in Israel

Acta Paediatrica, EarlyView.
ABSTRACT Aim To evaluate 25‐year national trends in paediatric intensive care utilisation, patient outcomes, rehospitalisations and regional resource distribution in Israel. Methods Retrospective, population‐based cohort study of all paediatric (0–17 years) ICU hospitalisations in Israel between 1999 and 2023.
Yael Applbaum, Shulamit Gordon, Isaac Manaster, Ziona Haklai, Joseph Mendlovic, Adi Avniel Aran, Uri Pollak   +6 more
wiley   +1 more source

Catheterisation after urethral lengthening in transgender/gender‐diverse individuals: a randomised controlled trial (Safe Access for Bladder Entry in Transgender Men Following Penile Reconstruction [SAFE])

BJU International, EarlyView.
Objective To conduct a randomised controlled trial (RCT) to assess the efficacy of the Urethrotech urethral catheterisation device (UCD®; Urethrotech Ltd., Kingston Upon Thames, Surrey, UK) catheter compared to a standard Foley catheter for catheterisation in post‐phalloplasty transgender and gender diverse (TGD) individuals following urethral ...
Anastasia Frost, Andrea Gobbo, Nim Christopher, David Ralph, Wai Gin Lee   +4 more
wiley   +1 more source

Endemic Coronavirus Infections are Associated with Strong Homotypic Immunity in a US Cohort of Children from Birth to 4 Years. [PDF]

J Pediatric Infect Dis Soc
Morrow AL, Payne DC, Conrey SC, McMorrow M, McNeal MM, Niu L, Burrell AR, Schlaudecker EP, Mattison C, Burke RM, DeFranco E, Teoh Z, Wrammert J, Atherton LJ, Thornburg NJ, Staat MA.   +15 more
europepmc   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Inactivated Split MERS-CoV Antigen Prevents Lethal Middle East Respiratory Syndrome Coronavirus Infections in Mice. [PDF]

Vaccines (Basel)
Seo H, Jang Y, Kwak D.
europepmc   +1 more source

Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries

British Journal of Pharmacology, EarlyView.
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley   +1 more source

PLGA‐particle‐based vaccine induces SARS‐CoV‐2‐specific antibody and T‐cell responses

British Journal of Pharmacology, EarlyView.
A novel coronavirus disease 2019 (COVID‐19) vaccine encapsulating recombinant severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) spike receptor binding domain (RBD) with the double stranded RNA (dsRNA) analogue Riboxxim induces robust systemic and respiratory T‐ and B‐cell responses in mice.
Dennis Horvath, Katharina Inholz, Dennis Mink, Alicia Madel, Julia Koerner, Reinhold Horlacher, Michael Basler   +6 more
wiley   +1 more source

Mast Cells in Acute COVID‐19 Patients

Allergy, EarlyView.
Ilan Zaffran, Hadas Pahima, Eli Ben‐Chetrit, Amir Jarjoui, Ilaria Puxeddu, Carl Zinner, Joana Vitte, Alexandar Tzankov, Francesca Levi‐Schaffer   +8 more
wiley   +1 more source

Pandemic of coronavirus infection

Indian Journal of Physical Therapy and Research, 2020
openaire   +1 more source