Results 261 to 270 of about 402,323 (301)

The role of macrophage migration inhibitory factor (MIF) in the pathogenesis and progression of cardiovascular disease

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam   +4 more
wiley   +1 more source

Mutational Signature‐Based Biomarker for Phase II Trial of Olaparib Maintenance in Advanced High‐Grade Ovarian Cancer

open access: yesCancer Science, EarlyView.
A whole‐exome sequencing–based mutational signature biomarker (MSBM) identified an HRD‐enriched population in advanced ovarian cancer. In a phase II trial, olaparib maintenance suggested clinically meaningful PFS benefit without bevacizumab, supporting MSBM as a complementary HRD assessment approach.
Katsutoshi Oda   +20 more
wiley   +1 more source

Advancing FAIR phylogenetics for health threats: a systematic review of SARS‐CoV‐2 research and guidelines for future outbreaks

open access: yesCladistics, EarlyView.
Abstract During the COVID‐19 pandemic, the need for quick public health action often conflicted with the careful methods required in phylogenetics. To explore this, we reviewed 217 SARS‐CoV‐2 studies published from January 2020 to March 2025 in 121 journals.
Omkar Marne, Denis Jacob Machado
wiley   +1 more source

The economic effect of discrimination: Evidence from the restaurant sector

open access: yesContemporary Economic Policy, Volume 43, Issue 2, Page 226-259, April 2025.
Abstract Discrimination often leads to economic consequences for affected groups. This study examines the economic impact of consumer discrimination on Chinese restaurants in the U.S. during the COVID‐19 pandemic's onset. Using cell phone data and revenue records, it identifies a significant −10% relative decline in visits to Chinese restaurants by ...
Guanting Yi
wiley   +1 more source

COVID‐19's Shadow: The Effect of COVID‐19 on Cytopathology Specimens Received at an Academic Laboratory in Central South Africa

open access: yesCytopathology, EarlyView.
Due to global COVID‐19‐related disruptions in healthcare delivery, cytopathology laboratories experienced a reduction in specimen volume that did not fully recover post‐COVID‐19. The findings of the study highlighted the importance of resilient diagnostic services during health crises.
Courtney T. A. Bonato   +2 more
wiley   +1 more source

Clinical predictors of mortality in immune thrombotic thrombocytopenic purpura: A National Inpatient Sample analysis

open access: yes
British Journal of Haematology, EarlyView.
Anand Shah   +4 more
wiley   +1 more source

Frontline Healthcare Professionals' Perceptions of the Duty to Care During the COVID‐19 Pandemic: A Multi‐Method Study in Mozambique

open access: yesDeveloping World Bioethics, EarlyView.
ABSTRACT COVID‐19 intensified ethical tensions between clinicians' duty to care and self‐protection amid PPE shortages. We explored frontline healthcare professionals' perspectives in Maputo, Mozambique. Semi‐structured interviews with healthcare professionals at four hospitals (April–June 2022) were recorded in Portuguese, transcribed, and ...
Ângela Alface   +5 more
wiley   +1 more source

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